A5078779883- Neonatal Respiratory Health Research
- Neonatal Health and Biochemistry
- Infant Development and Preterm Care
- Congenital Diaphragmatic Hernia Studies
- Infant Nutrition and Health
- Neonatal and fetal brain pathology
- Retinopathy of Prematurity Studies
- Respiratory Support and Mechanisms
- Neuroscience of respiration and sleep
- Methemoglobinemia and Tumor Lysis Syndrome
- Neonatal and Maternal Infections
- Birth, Development, and Health
- Hemoglobinopathies and Related Disorders
- Breastfeeding Practices and Influences
- Metabolism and Genetic Disorders
- Cardiovascular Conditions and Treatments
- Blood groups and transfusion
- Congenital Heart Disease Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Heme Oxygenase-1 and Carbon Monoxide
- Clinical Nutrition and Gastroenterology
- Retinal Diseases and Treatments
- Assisted Reproductive Technology and Twin Pregnancy
- Thyroid Disorders and Treatments
- Erythrocyte Function and Pathophysiology
Agostino Gemelli University Polyclinic
2011-2023
Università Cattolica del Sacro Cuore
2009-2022
Catholic University of America
2001-2015
University of the Sacred Heart
2004-2014
Sapienza University of Rome
2011-2014
Faculty (United Kingdom)
1996-2014
Società Italiana di Nefrologia
2014
Pontifícia Universidade Católica de São Paulo
2008-2012
Istituto Superiore di Sanità
2012
Istituto di Sessuologia Clinica
2012
Acute bronchiolitis is the leading cause of lower respiratory tract infection and hospitalization in children less than 1 year age worldwide. It usually a mild disease, but some may develop severe symptoms, requiring hospital admission ventilatory support ICU. Infants with pre-existing risk factors (prematurity, bronchopulmonary dysplasia, congenital heart diseases immunodeficiency) be predisposed to form disease. Clinical diagnosis manly based on medical history physical examination...
OBJECTIVES. We sought to verify the association between maternal intrahepatic cholestasis of pregnancy (ICP) and neonatal respiratory distress syndrome (RDS) determine how bile acids levels alter risk developing RDS. METHODS. extracted data from our divisional database about all newborns born during years 2000–2004. compared 77 neonates pregnancies complicated by ICP with 427 in same range gestational age noncomplicated pregnancies. studied immediately before delivery mothers measured acid...
Summary Dravet syndrome (DS) is an epileptic encephalopathy related mainly to mutations in the SCN1A gene, encoding for neuronal sodium channels. Patients with DS have a high risk of sudden unexpected death epilepsy (SUDEP). In this study we investigated whether patients present abnormalities electrical and autonomic cardiac function. To aim assessed ventricular repolarization heart rate variability (HRV) on standard electrocardiography (ECG) 24‐h ECG Holter monitoring, respectively, 20...
To assess the correlation of echocardiographic signs myocardial damage to serum cardiac troponin T (cTnT) concentrations in newborn infants with perinatal asphyxia.Electocardiograms (ECG) and echocardiograms (Echo) were obtained during first 24 h life from 29 asphyxiated 30 control correlated cTnT concentrations. The parameters included systolic ventricular performance, preload, afterload, diastolic function, stroke volume (SV), left output (LVO), hyperechogenity papillary muscles...
Saliva is a body fluid of unique composition devoted to protect the mouth cavity and digestive tract. Our high performance liquid chromatography (HPLC)-electrospray ionization-MS analysis acidic soluble fraction saliva from preterm human newborn surprisingly revealed more than 40 protein masses often undetected in adult saliva. We were able identify following proteins: stefin A B, S100A7 (two isoforms), S100A8, S100A9 (four S100A11, S100A12, small proline-rich 3 lysozyme C, thymosins β(4)...
OBJECTIVE: The aim of this study was to investigate whether ibuprofen exposure associated with increased hyperbilirubinemia in preterm infants. METHODS: Since 2000, has been administered all infants at <30 weeks gestation who are admitted our unit, prevent patent ductus arteriosus. We retrospectively compared data for 418 subjected prophylaxis (2000–2007) and 288 not exposed (1993–1999). RESULTS: group had a significantly higher peak total serum bilirubin level (9.0 ± 2.5 mg/dL vs 7.3...
Neonatal respiratory distress syndrome is associated with intrahepatic cholestasis of pregnancy, and bile acids may play a major role in neonatal acid pneumonia. Our aim was to demonstrate the presence bronchoalveolar lavage fluid neonates affected by who were born from pregnancy investigate mechanisms action acute lung injury.In this prospective study, we enrolled 10 delivered requiring mechanical ventilation (intrahepatic group) 2 control groups. The first group consisted 20 infants...
OBJECTIVES. The objectives of this study were to (1) assess visual function in low-risk preterm infants at 35 and 40 weeks' postmenstrual age, (2) compare abilities term-equivalent age with term-born infants, (3) evaluate effects extrauterine life on early function. METHODS. Visual was assessed by using a validated test battery 109 who born <31 gestation. findings compared data from collected the same protocol. RESULTS. All completed both assessments. 35-week responses generally less...
An important contribution to the variability of any proteome is given by time dimension that should be carefully considered define physiological modifications. To this purpose, whole saliva was investigated in a wide age range. Whole collected from 17 preterm newborns with postconceptional at birth 178-217 days. In these subjects sample collection performed serially starting immediately after and within about 1 year follow-up, gathering total 111 specimens. Furthermore, 182 aged between 0...