A5009509422- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- COVID-19 epidemiological studies
- COVID-19 diagnosis using AI
- Immunotherapy and Immune Responses
- Adolescent and Pediatric Healthcare
- Child and Adolescent Health
- Immune Response and Inflammation
- Atomic and Subatomic Physics Research
- Cancer Risks and Factors
- RNA Interference and Gene Delivery
- Immune Cell Function and Interaction
- Endometrial and Cervical Cancer Treatments
- Pediatric health and respiratory diseases
- Breast Cancer Treatment Studies
- Zoonotic diseases and public health
- Particle physics theoretical and experimental studies
- Quantum Chromodynamics and Particle Interactions
Southern Medical University
2025
Tianjin University of Traditional Chinese Medicine
2025
Huazhong Agricultural University
2024
Ministry of Education of the People's Republic of China
2024
Fudan University
2024
Guangzhou Center for Disease Control and Prevention
2020-2022
IntroductionImmune-mediated inflammatory diseases (IMIDs) are chronic caused by immune system dysregulation, affecting multiple systems and organs. Children adolescents aged 10–24 among the high-risk groups, global burden is substantial.MethodsUsing latest data from of disease (GBD) 2021, we employed Joinpoint regression analysis, Socio-Demographic Index (SDI) correlation cross-national equity analysis to elucidate spatiotemporal differences in IMIDs 10-24-year-olds 1990 2021.ResultsThe...
Objective: Hyperuricemia (HUA) is a metabolic disease that threatens human health. The role of Penthorum chinense Pursh. (PCP) in the treatment HUA has begun to receive attention recent years. This study aimed investigate effects and potential mechanisms PCP treatment. Methods: A murine model was induced C57/BL6 mice using potassium oxonate (PO) adenine (AD). Serum uric acid (SUA) measured ultra-performance liquid chromatography (UPLC). creatinine (Scr) detected creatine oxidase assay kit,...
Background COVID-19 screening is an effective nonpharmaceutical intervention for identifying infected individuals and interrupting viral transmission. However, questions have been raised regarding its effectiveness in controlling the spread of novel variants high socioeconomic costs. Therefore, optimization strategies has attracted great attention. Objective This review aims to summarize evidence provide a reference basis prevention control COVID-19. Methods We applied methodological...
Objective: To analyze the contagiousness and secondary attack rate of 2019 novel coronavirus in cluster epidemics Guangzhou provide evidence for prevention control COVID-19. Methods: All individuals identified to be infected with 2019-nCoV Guangzhou, including confirmed cases asymptomatic cases, were included classified as imported local cases. The first case each epidemic was defined index case, number subsequent infections calculated evaluate shortest incubation period 1-3 days. Results:...
The controlled release of immunostimulatory agents represents a promising strategy to enhance vaccine efficacy while minimizing side effects. This study aimed improve the RBD-Fc-based COVID-19 through combining an iNKT cell agonist and TLR7/8 using covalent conjugation temporal delivery. We hypothesized that these combinations would yield more balanced Th1/Th2 immune response. For conjugation, we employed uncleavable linker self-immolative disulfide conjugate α-galactosylceramide (αGC)...
Objective: To describe the distributions of demographic and clinic pathological characteristics relations with survival on female breast cancer patients in Guangzhou from 2008 to 2017. Methods: The baseline information subjects was obtained registry outcomes were Cancer Follow-up System Guangzhou. Kaplan-Meier used calculate 1-, 3-, 5-year overall rates. Univariate multivariate Cox proportional hazards regression models identify factors related survival. Results: Among 12 465 recruited...
Objective: To understand the epidemiological characteristics of two local COVID-19 outbreaks caused by 2019-nCoV Omicron variant in Guangzhou, such as incubation period, serial interval, basic reproductive number (R0) and influence gathering places on R0, provide evidence for prevention control infection. Methods: The data daily confirmed cases infection from April 8 to May 8, 2022 Guangzhou were collected model fitting. Weibull, Gamma lognormal distribution used estimate period interval....
Objective: To understand the epidemiological characteristics of three local COVID-19 epidemics in Guangzhou and provide reference for optimizing strategies measures prevention control. Methods: The data cases reported as June 18, 2021 were collected from National Notifiable Disease Report System China. software Excel 2019 SPSS 22.0 applied cleaning statistical analysis. Results: A total 726 Guangzhou. In epidemic associated with outbreak Hubei province, 366 reported. Most female (51.6%,...
<sec> <title>BACKGROUND</title> COVID-19 screening is an effective nonpharmaceutical intervention for identifying infected individuals and interrupting viral transmission. However, questions have been raised regarding its effectiveness in controlling the spread of novel variants high socioeconomic costs. Therefore, optimization strategies has attracted great attention. </sec> <title>OBJECTIVE</title> This review aims to summarize evidence provide a reference basis prevention control...