A5017538137- Radiopharmaceutical Chemistry and Applications
- Prostate Cancer Treatment and Research
- Medical Imaging Techniques and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Liver Disease and Transplantation
- Radiomics and Machine Learning in Medical Imaging
- Renal cell carcinoma treatment
- Lung Cancer Research Studies
- Effects of Radiation Exposure
- Cancer Diagnosis and Treatment
- Breast Lesions and Carcinomas
- Acute Myocardial Infarction Research
- Healthcare Systems and Public Health
- Neuroendocrine Tumor Research Advances
- Cardiac Health and Mental Health
- Endometrial and Cervical Cancer Treatments
- Renal and related cancers
- Breast Cancer Treatment Studies
- Ultrasound and Hyperthermia Applications
- Ovarian cancer diagnosis and treatment
- Management of metastatic bone disease
- Medical and Biological Sciences
- Chemical Reactions and Isotopes
P.A. Hertzen Moscow Oncology Research Institute
2018-2024
Ministry of Health of the Russian Federation
2018-2024
Medical Radiological Research Center
2023
Ministry of Health
2021
Petrozavodsk State University
2018
Objective. Background 99mTc-technephyt hepatobiliary scintigraphy (HBS) and 13C-methacetin breath test were used as a quantitative methods to evaluate liver function. The aim of this study was compare future remnant function assessed by dynamic with results methacetin in the prediction failure after major resection. Materials methods. Methacetin performed prior resection 53 high-risk patients, including 48 patients hepatic metastases from colorectal cancer 5 hepatocellular carcinoma . Liver...
Purpose of the study. Improvement results treatment in patients with primary and metastatic liver cancer by decreasing risk post-resection failure on basis evaluation functional reserves liver. Materials Methods. The study included two independent samples operated about or lesions at Department abdominal Oncology, P. A. Hertsen MORI. first group 53 who carried out 13C-breath test metallimovie dynamic scintigraphy preoperative stage addition to standard algorithm examination. Patients 2nd...
Purpose. To assess the additional contribution of SPECT/CT, used in conjunction with planar osteoscintigraphy, bone metastatic disease detection and its effect on tactics managing patients breast cancer prostate cancer. Materials methods. The study included 1412 established oncological diagnosis (breast — 844 patients, 568 patients), to which «whole body» SPECT/CT were performed. In all study, fact was by results imaging techniques follow up. Results. Bone detected 324 (23%) excluded 1088...
The article presents the results of 5-years follow-up for patients who had acute coronary syndrome. hospital treatment were demonstrated. In addition, study showed adherence to therapy, long-term consequences and clinical outcomes following syndrome in practice Republic Karelia
It is established that prostate-specific membrane antigen (PSMA), despite its name, expressed in many tissues other than the prostate gland, both within physiological conditions and various pathological processes. Additionally, apart from cancer, malignant tumors are characterized by increased PSMA expression which, according to authors, associated with neoangiogenesis. These factors reflected results of PSMA-radioligand imaging require comprehensive approach image interpretation including...
Оne of the most commonly used fluorine‑18 labeled prostate-specific membrane antigen (PSMA) ligands in positron emission tomography combined with computed (PET/CT) is [ 18 F]PSMA‑1007. In comparison to other clinically available PSMA radioligands characterized by renal clearance, F]PSMA‑1007 exhibits predominantly hepatobiliary excretion. It allows a better assessment pelvic area patients prostate cancer (PCa). Nevertheless, our clinical practice, we routinely observed notably high uptake...
In present days positron emission tomography combined with X-ray computed (PET/CT) is a highly informative, actively developing method of visualization in oncology, and particular oncourology. It widely used to determine the localization biochemical recurrence (BR) prostate cancer (PCa). This survey article presents modern trends prospects development PET BR PCa. shows diagnostic capabilities PET/CT various radiopharmaceuticals, including ligands for prostate-specific membrane antigen...
ПРОГНОСТИЧЕСКАЯ ЦЕННОСТЬ ПЭТ/КТ С 18F-ФДГ В ОПРЕДЕЛЕНИИ СТАТУСА МУТАЦИИ ГЕНА EGFR У ПАЦИЕНТОВ НЕМЕЛКОКЛЕТОЧНЫМ РАКОМ ЛЕГКОГО
This article presents a clinical case demonsratinga high metastatic potential of clear cell renal carcinoma combined with atypical metastases to breast and paranasal sinuses. The prevalence lesions the sinuses in various malignant tumors depending on their morphological forms is analyzed. authors present an analysis data published for last 30 years. optimal diagnostic algorithms detect progression evaluate effectiveness treatment are considered.
This article presents a modern possibilities and future path of prostate-specific membrane antigen (PSMA) radiopharmacuticals labeled by 99m Tc, that is the most popular isotope using in conventional nuclear medicine. The main advantages disadvantages SPECT/CT with these radiopharmaceuticals different phases prostate cancer continuum have been analyzed. Results research diagnostic sensitivity Tc-PSMA including comparison 68 Ga-PSMA PET/CT modality such as MRI bone scan are presented....
The pain syndrome accompanying metastatic damage of bones, significantly reduces quality patients life. In recent decades, medical practice implemented methods systemic radionuclide therapy bone metastases using different radionuclides, which allows to stop both the and progression disease. Results their application give grounds consider perspective development in nuclear medicine direction on treatment defeats by means therapy.
In recent years, there is a steady tendency of increase in the number minimally invasive, organ safety surgical treatment thoracic oncology, such as video-assisted thoracoscopic segmentectomy, requiring maximal information about broncho- and angioarchitectonics affected lung segment. The use multislice computed tomography postprocessing software packages allows to get highly informative three-dimensional reconstruction broncho-vascular structures that contribute individual approach admission.
Previously, low-dose radiation therapy was used for pneumonia treatment. We aimed to investigate the safety and effectiveness of carbon nanoparticles labeled with Technetium isotope (99mTc) in a form ultradispersed aerosol combination standard COVID-19 therapy. The study randomized phase 1 2 clinical trial radionuclide inhalation patients related pneumonia.We enrolled 47 confirmed infection early laboratory signs cytokine storm them into Treatment Control groups. analyzed blood parameters...
INTRODUCTION: Positron emission tomography combined with computed (PET/CT) prostate-specific membrane antigen-targeted (PSMA) radiopharmaceuticals is a valuable method for prostate cancer (PCa) imaging. Both 68Ga- and 18F-labelled PSMA ligands are used in clinical practice now, example, 18F-PSMA-1007. Currently there no consensus on time interval between 18F-PSMA-1007 administration scanning start that served as the basis this study. OBJECTIVE: The aim of study was to determinate optimal at...
This article provides a comparative review of two systems for standardized evaluation the results hybrid PET imaging with radiolabeled PSMA ligands – PROMISE and PSMA-RADS version 1.0. The principles classification, nomenclature algorithms, as well recommendations structuring research conclusion protocols, highlighting advantages disadvantages proposed systems, are considered in detail.
Positron emission tomography coupled with computed (PET/CT) has proven to be highly informative in the diagnosis of various malignant tumours. PET/CT examination takes into account biological and morphological data, which allow accurate tumour localisation full staging disease, respectively. Cervical cancer (CC) is one most common, high-mortality cancers women. The effectiveness CC treatment depends on early diagnosis, connected assessment local spread metastatic lymph node involvement...
Neuroendocrine tumors (NEТ) are a heterogeneous group of neoplasms various locations originating from the APUD system cells with biologically active properties. Although immunohistochemical assay for Ki-67 has been proved to have prognostic significance in GEP-NENs, pitfalls may lead misjudgment tumor grades, prognosis and during treatment planning due presence varying degrees differentiation proliferative activity within single lesion, as well entire neoplastic process. These features can...