Background: This is a prospective study. Atrophic vulvovaginitis (VVA), prevalent condition resulting from estrogen deficiency after the menopause, characterized by symptoms such as vaginal dryness, itching, burning, dyspareunia, and urinary discomfort. Standard treatment involves systemic replacement therapy (HRT) localized treatments, estriol. However, many women with moderate-to-severe VVA may not fully benefit alone. Non-hormonal adjunctive pelvic floor exercises (e.g., Kegel exercises),...

Balneotherapy, treating diseases by bathing in mineral-rich waters and mud, has a long historical application across various cultures. Despite its widespread use, comprehensive studies on biological impacts are scant, particularly quantifying effects at the cellular systemic levels. This study aims to rigorously investigate of therapeutic mud mineral waters, providing scientific basis for their clinical application. We focused elucidating mechanisms behind observed determining these natural...

Massage therapy, a traditional practice, has garnered interest for its potential applications in reproductive health, particularly enhancing fertility and hormonal balance. This study investigates the impact of ovulation-inducing massage on monthly ovulation rates among women seeking assessment. Methods: Conducted at Santerra Medical Center, this three-month involved 60 divided into two groups: one receiving therapy (n=32) control group without (n=28). Ovulation was monitored using...

Abstract Background. Balneotherapy is a stimulation - adaptation treatment method applied in the forms of bathing, drinking, and inhalation cures performed with natural therapeutic factors, which acting three main ways: thermally, mechanically, chemically. Mud or peloids are factors formed by processes under influence biological geological phenomena, finely dissolved state mixed water (mud) used medical practice form baths local procedures. Objective. This systematic review aims to...

Abstract Sapropelic muds have been used for centuries to treat various illnesses, but their effects and mechanisms are still under research. In this study the of Techirghiol sapropelic mud on tissue oxygenation in elderly patients diagnosed with neuromuscular disorders were investigated using spatial spectral information provided by hyperspectral imaging technique. A group 38 which they received therapy was studied. applied lumbar region each patient 30 min, directly skin a thick layer,...

Abstract: Oxygen is essential for cellular respiration and energy production. Tissue oxygenation refers to delivering oxygen cells throughout the body. Microcirculation brings blood through small sanguine vessels maintain cells' supply of nutrients oxygen. Optimal tissue ox-ygenation microcirculation are maintaining healthy tissue. Conversely, poor can cause damage, impair wound healing, increase infection risk. Several factors affect microcirculation, including age, lifestyle (such as...

Breast-conserving surgery (BCS) in case of breast cancer and/or in-situ-carcinoma lesions (DCIS) intends to completely remove while saving healthy tissue as much possible achieve better aesthetic and psychological outcomes for the patient. Such modality should result postoperative tumor-free margins surgical resection order carry on with next therapeutical steps patient care. However, 10-40% patients undergo more than one procedure acceptable cancer-negative margins. A 2nd operation or...

The study aims to characterize Techirghiol's sapropelic mud both by determining the organic and inorganic composition of constituent phases isolating some compounds humic substances.The distribution between solid liquid peloid Ca2+, Mg2+, Fe3+cations, PO43-anion, bioactive protein, lipid carbohydrate classes as well phosphatase activity Techirghiol are analyzed.The is fractionated using pH solvent polarity variation spectrophotometrically characterized based on absorption in wavelength range...

This study aimed to evaluate the efficacy of Kegel exercises, or pelvic floor muscle training (PFMT), in reducing symptoms urinary incontinence among women with overactive bladder (OAB) and mixed (MUI). A randomized control trial was conducted a total 50 participants (young ages 18-35) out which 35 were diagnosed OAB 15 MUI. The monitored for six months: In first three months received only pharmacological therapy, solifenacin succinate 10 mg per day, after this period same group associated...

This study represents a morphometric assessment of the anterior segment lumbar spine, focused on vertebral body - intervertebral disk assembly, calculating some specific indicators and then completing direct morphometry data with resulting from imaging interpretation subsequently correlating same to map an anatomic-imaging model. The was carried out anatomic items personal archive images obtained Computer Tomography (CT) Magnetic Resonance Imaging (MRI) assessment. for disks, height in...

Context and objective.The new insights in the pathogenesis of osteoarthritis (OA) reveal implications adipocytokines.This study aims to analyze correlations between serum value adiponectin clinical rehabilitation effects patients diagnosed with knee OA, admitted treated complex balneal resort Techirghiol lake.Subjects methods.The prospective randomized included 23 group, OA according ACR criteria, a matching control group subjects.Serum level (using ELISA technique), uric acid,...

Up till now, to our knowledge, there are no studies evaluating serum Brain - Derived Neurotrophic Factor (BDNF) levels in patients with degenerative chronic low back pain under rehabilitation treatment. BDNF is a neuroprotein associated neuropathic and represents an important mediator of the effects physical exercise. Complex balneal treatment hot Techirghiol sapropelic mud reduces increases these patients.

Introduction. Low back pain has a direct and proportional impact on function general one the quality of life. The present study aims to evaluate functional low using specific self-assessment tools as indexes appreciation epidemiological correlations potential risk factors involved. conceptual model our research is based importance correlating symptoms with clinical assessment, scales pain, disability, life, determination these areas determined pathology. Material method. group made up 106...

Obesity is a complex, multifactorial metabolic pathology, within the path of modification endocrine system plays significant role. Changes in growth hormone (GH) and in-sulin factor (IGF) have been associated with obesity various ways, mainly through changes GH-binding proteins, insulin ghrelin levels. The balneal treat-ment Techirghiol Romanian sapropelic mud has an important impact on endo-crine system, primarily action hypothalamic-pituitary-adrenal axis. We investigated secretory IGF-1...

Background: The purpose of this study was to investigated cases spinal cord injury (SCI) during the years 2017-2021, in Constanta County (Romania) update data on SCI and thus identify trends region Romania. Methods: retrospectively analysed patients with Constanța County, whose (medical records) were provided us by Romania Motivation Foundation. This analysis made for period January 1, 2017 - August 31, 2021. Results: Ninety-six new traumatic reported between 2021 County. It found that...

Introduction. Osteoporosis is a disease of the entire skeleton, characterized by decrease bone mass and microarhitectural alterations tissue, which result in increased fragility predisposition to fractures. Materials methods. Accesing standard medical databases: Medline, Embase, Database, Pubmed Cochrane Register Controled Studies review new pharmacological studies non-pharmacological terapies osteoporosis. Statistical analysis performed from data extracted observation sheets June 2019...

Abstract Introduction. Glucocorticoids provide a significant resource of scientific progress in medical research, being studied terms molecules, genetics, physiopathology at the level human body, starting from animal models, with valuable recent discoveries regarding their implications psychic level, stress reaction and search new possible therapeutic effects unknown until now. Our work are illustrated correlations between serum cortisol body mass index - BMI old patients under balneal...