Pietro Seghini
A5002034538- Global Cancer Incidence and Screening
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Cervical Cancer and HPV Research
- Brain Metastases and Treatment
- Glioma Diagnosis and Treatment
- Liver Diseases and Immunity
- Lung Cancer Treatments and Mutations
- Childhood Cancer Survivors' Quality of Life
- Economic and Financial Impacts of Cancer
- Endometrial and Cervical Cancer Treatments
- Diabetes and associated disorders
- Growth Hormone and Insulin-like Growth Factors
- Pancreatitis Pathology and Treatment
- Palliative Care and End-of-Life Issues
- Cancer survivorship and care
- Pleural and Pulmonary Diseases
- HER2/EGFR in Cancer Research
- Genetic factors in colorectal cancer
- Patient-Provider Communication in Healthcare
- Neuroscience and Music Perception
- Gastrointestinal disorders and treatments
- Eosinophilic Esophagitis
- Acute Lymphoblastic Leukemia research
Azienda Unità Sanitaria Locale Piacenza
2015-2024
Guglielmo da Saliceto Hospital
2009-2024
Public Health Department
2024
Ospedaliera di Piacenza
2007-2021
Swiss Cancer League
2021
Institut National du Cancer
2021
Cancer Institute (WIA)
2021
Cancer Research Foundation
2021
London School of Hygiene & Tropical Medicine
2021
Centre International De Reference Chantal Biya
2021
Objectives : The IGF system is central to fetal growth. Recently, the relationships between cytokines and have been shown in specific tissues. It unknown whether these occur placenta. aim of this study was assess interleukin-6 (IL-6) modulated system. Methods Whole villous tissue cord serum were collected from growth restriction (FGR) neonates diagnosed before birth with altered Doppler velocimetry controls. Sixteen FGR 20 controls, born after week 32 gestation elective Caesarean sections,...
Malignant pleural effusion (MPE) is an extremely common problem affecting cancer patients, and thoracentesis essential procedure in attempt to delineate the etiology of fluid collections relieve symptoms affected patients. One most complications pneumothorax, which has been reported occur 20% 39% thoracenteses, with 15% 50% patients pneumothorax requiring tube thoracostomy. The present study was carried out assess whether thoracenteses performed ultrasound (US) guidance are associated a...
•Italy will have 4 million cancer survivors in 2030 (6.9% of the population), half diagnosed at least 10 years earlier.•From 2018 to 2030, complete prevalence increase by 1.5% per year.•As many as 7 out 8 prevalent cases same life expectancy general population.•Ten after diagnosis, 96% not die from cancer.•Prevalence estimates are essential improve consistent, data-driven control planning. BackgroundThe number and projections necessary meet healthcare needs patients, while data on cure...
Background & AimsThis cohort study compared colorectal cancer (CRC) incidence and mortality between people who participated in an Italian regional biennial fecal immunochemical test (FIT) screening program did not.MethodsThe started 2005. The target population included over 1,000,000 aged 50 to 69 years. FIT was a one-sample OC-Sensor (Eiken Chemical Co, Tokyo, Japan) (cutoff, ≥20 μg hemoglobin/g feces). average annual response rate invitation 51.4%. records of invited up June 2016 were...
This study aimed to evaluate the effectiveness of a biennial faecal immunochemical test (FIT) screening programme in reducing annual colorectal cancer (CRC) incidence its dynamic target population.The population included over 1,000,000 persons aged 50-69 living region northern Italy. The average response rate invitation was 51.4%. Each observed age-standardised (Europe) per 100,000 between 2005, year introduction programme, and 2016 compared with each expected as estimated age-period-cohort...
To describe the procedures to derive complete prevalence and several indicators of cancer cure from population-based registries. Cancer registry data (47% Italian population) were used calculate limited duration for 62 types by sex registry. The incidence survival models, needed completeness index (R) prevalence, evaluated likelihood ratio tests visual comparison. A sensitivity analysis was conducted explore effect on using different R indexes. Mixture models estimate net (NS); life...
Abstract This study aims to estimate long-term survival, cancer prevalence, and several cure indicators for Italian women with gynecological cancers. Thirty-one registries, representing 47% of the female population, were included. Mixture models used net fraction, time (when 5-year conditional survival becomes > 95%), prevalence (women who will not die cancer), already cured (living longer than cure). In 2018, 0.4% (121 704) alive after diagnosis corpus uteri cancer, 0.2% (52 551)...
Central nervous system (CNS) metastases from cancers of the gastrointestinal tract (GIT) are rare, and occur in 0.16-0.69% patients with gastric or gastro-esophageal (GE) junction cancer. Overexpression human epidermal growth factor 2 (HER-2) is associated poor prognosis absence HER-2-targeted therapy, an increased incidence CNS breast The role HER-2 overexpression not well known adenocarcinoma. purpose present retrospective study was to assess evaluate associations between status a series...
Abstract People alive many years after breast (BC) or colorectal cancer (CRC) diagnoses are increasing. This paper aimed to estimate the indicators of cure and complete prevalence for Italian patients with BC CRC by stage age. A total 31 Cancer Registries (47% population) data until 2017 were included. Mixture models allowed estimation net survival (NS); fraction (CF); time (TTC, 5‐year conditional NS >95%); (who will not die cancer); already cured (prevalent living longer than TTC). 2.6%...
The disclosure of a diagnosis cancer is complex, particularly in older patients for reasons related to the wishes family, fear discouraging patient, or patient's inability understand information. So our insight into people's perspectives regarding their fragmentary and inadequate. To examine views adults this issue, we performed prospective observational study an inpatient oncology clinic. From January 2006 June 2006, sample 132 consecutive aged over 70 years with variety solid tumors,...
Abstract Background Patients with severe thrombocytopenia are considered at risk for bleeding during invasive procedures as thoracentesis. The use of ultrasound (US) significantly reduces the rate pneumothorax from thoracentesis, but there is a lack data on safety and efficacy US guidance in reducing complications thoracentesis performed patients thrombocytopenia. Methods We retrospectively analysed cancer From January 2005 to December 2011, 462 underwent Procedures were divided into 2...
Breast cancer stage at diagnosis, patient age and molecular tumor subtype influence disease progression. The aim of this study was to analyze the relationships between these factors survival in breast patients among Italian population using data from AIRTUM national database. We enrolled women with primary 17 population-based registries. Patients were subdivided into older (>69 years), middle (50-69 years) younger groups (<50 their tumors categorized four subtypes based on hormone receptor...
(1) Background: Liver cancer in Italy is characterised by one of the highest incidence rates worldwide outside Asia coupled with comparatively favourable survival figures. The objective this study was to evaluate most recent epidemiologic trends disease. (2) Methods: Thirteen registries covering a population about 12,740,000 (21% national population) made available records 35,574 cases registered between 2003 and 2017. Trends age-standardised (Europe 2013) were analysed using results...
Introduction Chronic pancreatitis (CP) is characterized by irreversible morphologic and functional alterations of the pancreas, clinically presenting with upper abdominal pain as well exocrine endocrine insufficiencies. According to a more recent hypothesis, pathogenesis may involve genetic immunologic factors. Aim To investigate major histocompatibility complex (MHC) genes background chronic pancreatitis. Methodology Allelic polymorphisms were investigated in MHC region (HLA B, DRB, DQB)...
To evaluate cancer diagnosis disclosure in a cohort of patients attending an outpatient oncology unit, prospective observational study was performed. Three hundred twelve consecutive were accrued between January and June 2005. A questionnaire given to each patient; the questions very simple related demographics, residence, sex, educational background, employment status, time elapsed after diagnosis, treatment received, existence relatives, health insurance. All but one entered study. There...
Abstract Background Despite advance in resuscitation science, out of hospital cardiac arrest (OHCA) has an average survival rate only 10 %. Ventricular fibrillation (FV) is amenable to defibrillation, but deteriorates non shockable rhythms over time. It’Known that immediate cardiopulmonary and eraly defibrillation increase after OHCA. It remains unclear whether there association between gender survival. seems women OHCA patients are older, less likely have a witness they had fewer pubblic...