A5023737764- Characterization and Applications of Magnetic Nanoparticles
- Magnetic and Electromagnetic Effects
- Electromagnetic wave absorption materials
- Pickering emulsions and particle stabilization
- Surfactants and Colloidal Systems
- Electrohydrodynamics and Fluid Dynamics
- Magnetic properties of thin films
- Physiological and biochemical adaptations
- Additive Manufacturing and 3D Printing Technologies
- Monoclonal and Polyclonal Antibodies Research
- Biomimetic flight and propulsion mechanisms
- Cell Adhesion Molecules Research
- Electrospun Nanofibers in Biomedical Applications
- Microfluidic and Bio-sensing Technologies
- Advanced ceramic materials synthesis
- Minerals Flotation and Separation Techniques
- Adhesion, Friction, and Surface Interactions
- Photonic and Optical Devices
- Angiogenesis and VEGF in Cancer
- Aluminum Alloys Composites Properties
- Fluid Dynamics and Thin Films
- Advanced materials and composites
- Invertebrate Immune Response Mechanisms
- Avian ecology and behavior
- Innovative Microfluidic and Catalytic Techniques Innovation
Clemson University
2015-2023
University of Pennsylvania
2019-2020
Target (United States)
2019
Translational Therapeutics (United States)
2019
The vasculature is an essential component of the circulatory system that plays a vital role in development, homeostasis, and disease various organs human body. ability to emulate architecture transport function blood vessels integrated context their associated represents important requirement for studying wide range physiological processes. Traditional vitro models vasculature, however, largely fail offer such capabilities. Here we combine microfluidic three-dimensional (3D) cell culture...
This research is focused on the fabrication and properties of epoxy nanocomposites containing magnetized SiC whiskers (MSiCWs). To this end, we report an original strategy for magnetically active SiCWs by decorating with magnetic (iron oxide) nanoparticles via polymer–polymer (poly(acrylic acid)/poly(2-vinyl pyridine)) complexation. The obtained demonstrated a substantial response in polymerizing resin, application only 20 mT (200 G) field. We also found that chemically reacted causing...
Magnetic rotational spectroscopy (MRS) with magnetic nanoprobes is a powerful method for in-situ characterization of minute amounts complex fluids. In MRS, uniformly rotating field rotates micro- or nano-probes in the liquid and one analyzes features probe rotation to extract rheological parameters liquids. properties must be well characterized understood make results reliable reproducible. Ni Co nanorods synthesized by electrochemical template synthesis alumina membranes are discussed...
Viscosity determines the resistance of haemolymph flow through insect body. For flying insects, viscosity is a major physiological parameter limiting flight performance by controlling rate fuel to muscles, circulating nutrients and rapidly removing metabolic waste products. The more viscous haemolymph, greater energy needed pump it confined spaces. By employing magnetic rotational spectroscopy with nickel nanorods, we showed that in resting hawkmoths (Sphingidae) depends on wing size...
Abstract Blood clotting at wound sites is critical for preventing blood loss and invasion by microorganisms in multicellular animals, especially small insects vulnerable to dehydration. The mechanistic reaction of the clot first step providing scaffolding formation new epithelial cuticular tissue. clot, therefore, requires special materials properties. We have developed used nano-rheological magnetic rotational spectroscopy with nanorods quantitatively study nucleation cell aggregates that...
Mullite–nickel nanocomposite fibers with Ni nanoparticles of controllable size, dispersion, and consequent magnetic properties were fabricated using sol–gel/electrospinning method, followed by thermal reduction. The electrospun from an aqueous solution containing sol–gel mullite precursor nickel nitrate. These then heat treated in the reducing atmosphere between 550°C 750°C to achieve fine‐dis persed metallic (NPs). After 2+ was reduced NPs at for 10 h, directly transformed 1000°C without...
A novel design of a low-field magnetic stage for optical microscopy droplets and films within controlled environment is described. The consists five coils with 3D sensor in feedback control loop, which allows one to manipulate nano- microprobes microtesla fields. locally uniform time-dependent field the focal plane microscope objective enables rotate probes precisely set manner observe their motion. probe tracking protocol was developed follow rotation real time relate it viscosity host...
Targeted drug delivery to the endothelium has potential generate localized therapeutic effects at blood-tissue interface.For some cargoes, it is essential maintain contact with bloodstream exert protective effects.The pharmacokinetics (PK) of endothelial surface-targeted affinity ligands and biotherapeutic cargo remain a largely unexplored area, despite obvious translational implications for this strategy.To bridge gap, we site-specifically radiolabeled mono-(scFv) bivalent (mAb) specific...
Magnetic nanorods rotating in a viscous liquid are very sensitive to any ambient magnetic field. We theoretically predicted and experimentally validated the conditions for two-dimensional synchronous asynchronous rotation as well three-dimensional precession tumbling of an field superimposed on planar discovered that stabilizes nanorod so can be completely controlled. This effect opens up different applications sensors weak fields, microrheology, generally levitation.
In insects vulnerable to dehydration, the mechanistic reaction of blood after wounding is rapid. It allows minimize loss by sealing wound and forming primary clots that provide scaffolding for formation new tissue. Using nano-rheological magnetic rotational spectroscopy with nickel nanorods extensional rheology, we studied properties dripping from caterpillars Carolina sphinx moth ( Manduca sexta ) a high concentration cells. We discovered followed two-step scenario. First, in few seconds,...
Addressing the challenge of making ceramic thin films with in-plane-oriented nanorods, we propose to decorate nanorods magnetic nanoparticles and orient them using external field. As an illustration, mullite embedded oriented SiC were synthesized. The decorated Fe3O4 nanoparticles. A two-step processing route was developed when are first in a sacrificial polymer layer. Then, film aligned removed by heat-treatment. In second step, sol-gel/dip-coating method applied produce composite film....
In-situ characterization of minute amounts complex fluids is a challenge. Magnetic Rotational Spectroscopy (MRS) with submicron probes offers flexibility and accuracy providing desired spatial temporal resolution in nanoliter droplets thin films when other methods fall short. MRS analyzes distinct features the in-plane rotation magnetic probe, its moment makes full revolution following an external rotating field. The probe demonstrates distinguishable movement which changes from to tumbling...