A5100418983- Photosynthetic Processes and Mechanisms
- Light effects on plants
- Plant Genetic and Mutation Studies
- Natural product bioactivities and synthesis
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- RNA Research and Splicing
- Molecular Biology Techniques and Applications
- Pulmonary Hypertension Research and Treatments
- Circular RNAs in diseases
- Plant Molecular Biology Research
- Plant nutrient uptake and metabolism
- Metal Alloys Wear and Properties
- Extracellular vesicles in disease
- RNA modifications and cancer
- Phytochemistry and Biological Activities
- Inflammasome and immune disorders
- Inflammation biomarkers and pathways
- Genomics, phytochemicals, and oxidative stress
- Plant Stress Responses and Tolerance
- Welding Techniques and Residual Stresses
- Plant biochemistry and biosynthesis
- Plant-Microbe Interactions and Immunity
- Legume Nitrogen Fixing Symbiosis
- Topic Modeling
Tianjin Medical University General Hospital
2014-2025
Lanzhou University
2020-2024
First Hospital of Lanzhou University
2020-2024
Minzu University of China
2023-2024
Wuhan College
2024
Nanjing Agricultural University
2019-2024
Guangxi University
2023-2024
Northeast Agricultural University
2019-2024
Central Hospital of Zibo
2024
Anyang Institute of Technology
2023
Abstract The development of a successful radiation sensitivity predictive assay has been major goal biology for several decades. We have developed classifier that predicts the inherent radiosensitivity tumor cell lines as measured by survival fraction at 2 Gy (SF2), based on gene expression profiles obtained from literature. Our correctly SF2 value in 22 35 National Cancer Institute panel 60, result significantly different chance (P = 0.0002). In our approach, we treat continuous variable,...
Bone marrow mesenchymal stem cells (BMSCs) exhibit the capacity to self-renew and differentiate into multi-lineage cell types, including osteoblasts, which are crucial regulators of fracture healing. Thus, this study aims investigate effect microRNA (miR)-22-3p from BMSC-derived EVs on osteogenic differentiation its underlying mechanism.Extracellular vesicles (EVs) were isolated BMSCs taken up with BMSCs. Dual-luciferase reporter gene assay was used verify binding relationship between...
As a measure to enhance drying kinetics, efficiency, and quality of the whole American ginseng root, step-down relative humidity (RH) convective hot air strategy was experimentally investigated. The effects temperature (45, 50, 55, 60 °C), RH (20, 30, 40%), RH, continuous dehumidification, on characteristics attributes were examined. Results showed that effective moisture diffusion coefficient varied from 1.155 × 10−10 2.885 m2/s while activation energy found be 51.14 kJ/mol. Quality...
Pulmonary arterial hypertension (PAH) is a chronic disorder characterized by hyperproliferation of pulmonary smooth muscle cells (PASMCs). JMJD1C, member the Jumonji domain containing C (JMJC) histone demethylase family, contributes to cardiovascular dysfunction. However, role JMJD1C in PAH remains unknown. Mice were exposed hypoxia mimic several features associated with clinically. We found that was highly expressed lungs mice after exposure. knockdown ameliorated hypoxia-induced right...
<title>Abstract</title> Central airway obstruction can be secondary to extrinsic compression from surrounding structures, direct extension an adjacent tumor, metastatic disease and, less commonly primary intrinsic endobronchial malignancies.To our knowledge, nearly few reports of isolated central lesion by lymphoma without extrathoracic or extra-nodal manifestation have been published date. This is the first case about malignant trachea caused B-cell involvement main stem bronchi, lobar...
Siberian apricot (Prunus sibirica L.) has emerged as a novel potential source of biodiesel in China, but the molecular regulatory mechanism oil accumulation seed kernels (SASK) is still unknown at present. To better develop SASK woody biodiesel, it essential to profile transcriptome and identify full repertoire unigenes involved formation during different developing stages.We firstly detected temporal patterns for content fatty acid (FA) compositions 7 stages. The best time obtaining high...
Abstract Pulmonary arterial hypertension (PAH) is a progressive disorder characterized by vascular remodeling, endothelial cell (EC) dysfunction, and inflammation. The roles of microRNAs have received much critical attention. Thus, this study was attempted to show the biological function miR‐181a/b‐5p (miR‐181a/b) in monocrotaline (MCT)‐induced PAH. Here, rats injected with MCT were used as PAH models. expression miR‐181a/b its effect on pathologies examined using overexpression lentivirus....
Understanding the metabolic modulation of major quality traits during ripening is critical for fruit improvement in kiwifruits. Here, integrated proteomic and metabolomic profiling was undertaken to comprehensively examine dynamics kiwifruit ripening. This data set presents a global view pathways involved ripening, contributions key events regulation softening, amino acid metabolism, balance sugar accumulation organic glycolysis, tricarboxylic (TCA) were discussed. We suggested enzymes...
Mesenchymal stem cells (MSCs) confer therapeutic benefits in various pathologies and cancers by releasing extracellular vesicles (EVs) loaded with bioactive compounds. Herein, we identified bone marrow MSC (BMSC)-derived EVs harboring microRNA (miR)-29b-3p to regulate osteogenic differentiation through effects on the suppressor of cytokine signaling 1 (SOCS1)/nuclear factor (NF)-κB pathway via targeting lysine demethylase 5A (KDM5A) osteoporosis.We quantified miR-29b-3p BMSC-derived from...
Acidity is an important factor influencing the organoleptic quality of apple fruits. In this study, pyrophosphate-energized proton pump (PEPP) gene was isolated and designated MdMa12. On basis a phylogenetic analysis in Rosaceae species, PEPP genes were divided into three groups, with most closely related to pear genes. Gene expression revealed that high malic acid content generally accompanied by MdMa12 levels. Moreover, mainly expressed fruit. A subcellular localization suggested...
Diabetic retinopathy (DR) is a common complication of diabetes mellitus (DM) and it the main cause loss vision. In previous years, interest in biological activities marine organisms has intensified. The effect fucoidan from seaweed Fucus vesiculosus on molecular mechanisms numerous diseases been studied, while to date, its DR was yet be investigated. Therefore, aim present study evaluate role DR. human retinal pigment epithelial cell line ARPE‑19 exposed high D‑glucose presence or absence...
Abstract Lupus nephritis ( LN ) is a highly complex autoimmune disease caused by systemic lupus erythematosus SLE ). Micro RNA s (mi s) play vital role in the pathogenesis of . Previously, total 29 mi were identified to be down‐regulated patients, which miR‐410 was likely involved signalling transduction pathways regulating The purpose this study investigate and find out whether regulates expression interleukin IL )‐6 fibrosis It found that level kidney tissue MRL /lpr mice decreased...
Cotton is one of the most important crops in world. GDSL-type esterases/lipases (GELPs) are widely present all kingdoms and play an essential role regulating plant growth, development, responses to abiotic biotic stresses. However, molecular mechanisms underlying this functional diversity remain unclear. Here, based on identification GELP gene family, we applied genetic evolution simulation techniques explore cotton species. A total 1502 genes were identified 10 Segmental duplication...