A5084431350- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- Insect symbiosis and bacterial influences
- Toxin Mechanisms and Immunotoxins
- Glycosylation and Glycoproteins Research
- Yersinia bacterium, plague, ectoparasites research
- Bacillus and Francisella bacterial research
- Monoclonal and Polyclonal Antibodies Research
- Animal Disease Management and Epidemiology
- Viral Infections and Outbreaks Research
- Vector-borne infectious diseases
Defence Science and Technology Group
2009-2020
The Mapputta serogroup tentatively contains the mosquito-associated viruses Mapputta, Maprik, Trubanaman and Gan Gan. Interestingly, this has previously been associated with an acute epidemic polyarthritis-like illness in humans; however, there no ensuing genetic characterisation. Here we report complete genome sequences of Maprik viruses, a new group candidate, Buffalo Creek virus, isolated from mosquitoes detected by serology hospitalised patient. Phylogenetic analyses indicate that is one...
This report describes the near complete genomic sequence and subsequent analysis of Vinegar Hill virus (VINHV; tentative member genus Orthonairovirus, family Nairoviridae, order Bunyavirales). VINHV is second nairovirus reported to be isolated on mainland Australia first sequenced analysed. Our genetic shows that belongs Dera Ghazi Khan genogroup, a group viruses previously in other parts world including Asia, South Africa, USA. We discuss possible routes entry for nairoviruses into need...
Rhabdoviridae represent a diverse group of viruses with the potential to cause disease in humans, animals and plants. Currently there are nine genera family; however large number rhabdoviruses remain unassigned. Here we characterise three novel genomes. Almpiwar virus (ALMV), isolated from skinks northern Queensland, is first completely sequenced rhabdovirus squamates, serological studies indicating multiple animal host species. Harrison Dam (HARDV) Walkabout Creek (WACV) were mosquitoes...
The Mesoniviridae are a newly assigned family of viruses in the order Nidovirales. Unlike other nidoviruses, which include Coronaviridae, mesoniviruses restricted to mosquito hosts and do not infect vertebrate cells. To date there is little information on morphological antigenic characteristics this new group dearth mesonivirus-specific research tools. In study we determined genetic relationships recent Australian isolates Alphamesonivirus 4 (Casuarina virus—CASV) 1 (Nam Dinh virus—NDiV),...
DNA vaccines encoding different portions of the structural proteins western equine encephalitis virus were tested for efficacy their protection in a 100% lethal mouse model virus. The 6K-E1 protein encoded by vaccine conferred complete against challenge with homologous strain and limited heterologous strain.
Trubanaman (TRUV) and Gan (GGV) viruses are members of the tentatively assigned Mapputta group genus Orthobunyavirus within family Bunyaviridae. Despite reported associations with an acute polyarthritis-like illness in Australia, TRUV GGV have remained genetically uncharacterised. Here we report complete genome sequences which were originally isolated from mosquitoes 1966 1970, respectively. Sequence phylogenetic analyses indicate close relationships to other characterised group. These...
The complete genome sequences of three Ross River virus (RRV) isolates from infected Australian Defence Force (ADF) personnel and mosquitoes collected in ADF training areas were determined. Phylogenetic analysis comparison with all available RRV nucleotide GenBank split these into two distinct sublineages.
The complete genome sequences of two Barmah Forest virus (BFV) strains isolated from mosquitoes trapped in the Australian Defence Force (ADF) training areas during 2017 and 2018 reveal multiple nucleotide insertions 3' untranslated region (UTR) ADF BFV compared with prototype strain whole-genome sequence GenBank.