- Gout, Hyperuricemia, Uric Acid
- Case Reports on Hematomas
- Spondyloarthritis Studies and Treatments
- Inflammasome and immune disorders
- Vitamin D Research Studies
- Electrolyte and hormonal disorders
- Adrenal Hormones and Disorders
- Pharmacological Effects of Natural Compounds
VA Nasonova Scientific Research Institute of Rheumatology
2023-2024
The prevalence of hyperuricemia (HU), which can be considered the first stage gout formation, varies in different countries and tends to increase. Uric acid (UA), even its dissolved form, activates damage potentiates death articular cartilage cells through direct cytotoxicity a number other pathogenetic mechanisms. possible association HU osteoarthritis may due common mechanisms, but direction this relationship is still debatable issue. accumulated data suggest need for deeper study between...
Gout manifests as acute arthritis attacks, the frequency of which varies and is unpredictable. The aim this study was to identify factors associated with attacks in patients gout who have not received urate-lowering therapy (ULT). Materials methods. A retrospective cohort included 116 (6 females, 110 males) gout, a mean age 50.1±12.05 years, were receiving ULT. past year presence subcutaneous tophi evaluated. Analyzed alcohol consumption, smoking, body mass index (BMI), blood pressure...
The relationship between serum levels of vitamin D and uric acid (UA) in the blood may be bidirectional, yet remains unexplored patients with gout. aim this study was to identify association UA deficiency Materials Methods. This single-center observational included 79 a confirmed diagnosis gout (72 [91.1 %] men 7 [8.9 women) who were not receiving urate-lowering therapy (ULT). All underwent evaluation (UA), D, parathyroid hormone, C-reactive protein (СRP), creatinine, alanine...
Gout is a chronic disease characterized by attacks of arthritis, most often the lower extremities, which develop under conditions prolonged hyperuricemia caused environmental and/or genetic factors. In last decade, there has been an increase in prevalence both and gout, causes concern not only among rheumatologists, but also doctors related specialties. This due to fact that uric acid, deposited joints, other organs tissues, contributes development cardiovascular metabolic diseases, as well...
Hyperuricemia (HU) is a condition caused by an increase in serum uric acid (UA) levels above 360 μmol/l. Often HU asymptomatic, but under the influence of genetic and environmental factors, attacks peripheral arthritis (gout) may occur. Remission gout achieved normalization UA levels, which can be determined colorimetric or electrochemical method, although latter not currently commonly used clinical practice to control levels. Objective: compare standard methods (Easy Touch GCU Meter) for...