About
Contact & Profiles
A5039014005
Research Areas
- Immune Cell Function and Interaction
- Atherosclerosis and Cardiovascular Diseases
- T-cell and B-cell Immunology
- Chemokine receptors and signaling
University of Milan
2022
Activation of T cells relies on the availability intracellular cholesterol for an effective response after stimulation. We investigated contribution derived from extracellular uptake by low-density lipoprotein (LDL) receptor in immunometabolic cells. By combining proteomics, gene expression profiling, and immunophenotyping, we described a unique role provided LDLR pathway CD8+ cell activation. mRNA protein was significantly increased activated compared to CD4+ WT cells, this resulted...
10.1083/jcb.202202011
article
EN
cc-by-nc-sa
The Journal of Cell Biology
2022-08-09
10.1016/j.atherosclerosis.2022.06.113
article
EN
Atherosclerosis
2022-08-01
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