A5101836937- Carbon dioxide utilization in catalysis
- CO2 Reduction Techniques and Catalysts
- Asymmetric Hydrogenation and Catalysis
- Radical Photochemical Reactions
- biodegradable polymer synthesis and properties
- Organometallic Complex Synthesis and Catalysis
- Catalytic Alkyne Reactions
- Organoboron and organosilicon chemistry
Tsinghua University
2018-2022
Carbon dioxide (CO 2 ), as a one-carbon synthon, has many advantages such abundant, non-toxic, clean and so on.So the reactions using CO synthon have been widely concerned in organic chemistry.Transition-metalcatalyzed reaction of unsaturated hydrocarbons with to produce carboxylic acid is one most commonly-used method convert , organometallic reagents can be added reducing agent.This kind realized by strategy tandem reaction.In reaction, react transition-metal catalysts generate new situ...
Cheap and available formate can be seen formally as a carbon dioxide radical anion (CO2•-) combined with hydrogen atom, where the CO2•- is not only highly active but also very powerful reductant. In this paper, we successfully realized visible-light-driven carboxylation of benzyl bromides to prepare high-value arylacetic acids using potassium terminal This reaction characterized by mild conditions wide range substrates. Moreover, under nitrogen atmosphere, achieve utilizing an excess...
Lewis base promoted selective reduction of CO 2 into boryl formates by using BH 3 NH as a reductant under mild conditions has been reported. The formates, generated in situ, were shown to be reactive and versatile sources formyl compounds create new C–N, C–O, C–C bonds. reactivity the yield formic acid, formamides, secondary alcohols, benzoheterocyclic rings was investigated.
Abstract Cobalt‐catalyzed reductive carboxylation of aryl bromides with carbon dioxide has been developed. The reaction proceeded under one atm pressure CO 2 at 40 °C in the presence cobalt iodide/2,2′‐bipyridine catalysts and zinc dust as a reducing reagent. Various could be converted to corresponding carboxylic acids good high yields. Preliminary mechanistic experiments ruled out intervention intermediate organozinc species for , thus suggesting direct insertion into ArCoBr species. magnified image
Abstract A titanocene‐catalyzed regioselective carbocarboxylation of dienes or alkenes has been developed. This reaction proceeds efficiently to form flexible and versatile carboxylic acids in the presence n BuMgCl by combined use with organic halides CO 2 as carbon synthon carboxyl group, respectively. 2,3‐Disubstituted 1,3‐butadienes were used afford acrylic excellent yields various halides. In most cases, arylalkenes afforded benzylic high under similar conditions. The titanocene catalyst...
Cp2TiCl2-catalyzed carboxylation of aryl chlorides with carbon dioxide to afford benzoic acids in good yields has been achieved the presence n-BuMgCl. The reaction proceeds by a sequential magnesium halide exchange and CO2 wide variety under mild conditions.
Cobalt-catalyzed regioselective three-component arylcarboxylation of acrylate with aryl bromides and carbon dioxide has been developed. The reaction is carried out by using cobalt chloride as a precatalyst zinc powder reducing reagent under CO2 (1 atm) at 40 °C. A range are used for this reaction, leading to series valuable carboxylic acids high regioselectivity functional-group compatibility. Mechanistic experiments DFT calculations indicate that involves the enolate intermediate form C-C bond.