A5026823311- Tryptophan and brain disorders
- Fatty Acid Research and Health
- Diet and metabolism studies
- Stress Responses and Cortisol
- Bipolar Disorder and Treatment
- Schizophrenia research and treatment
- Maternal Mental Health During Pregnancy and Postpartum
- Eicosanoids and Hypertension Pharmacology
- Transcranial Magnetic Stimulation Studies
- Alcoholism and Thiamine Deficiency
- Treatment of Major Depression
- COVID-19 and Mental Health
- Circadian rhythm and melatonin
- Migraine and Headache Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Child and Adolescent Psychosocial and Emotional Development
- Long-Term Effects of COVID-19
- Birth, Development, and Health
- Mental Health Research Topics
- Intensive Care Unit Cognitive Disorders
- Electroconvulsive Therapy Studies
- Mental Health Treatment and Access
- Attention Deficit Hyperactivity Disorder
- Sleep and related disorders
- Functional Brain Connectivity Studies
China Medical University
2016-2025
China Medical University Hospital
2016-2025
An-Nan Hospital
2020-2025
University of Tübingen
2025
King's College London
2016-2025
Capital Normal University
2024-2025
King's College Hospital
2021-2025
China Medical University
2004-2024
Jewish General Hospital
2020-2024
Jinan University
2024
Researchers increasingly use meta-analysis to synthesize the results of several studies in order estimate a common effect. When outcome variable is continuous, standard meta-analytic approaches assume that primary report sample mean and deviation outcome. However, when skewed, authors sometimes summarize data by reporting median one or both (i) minimum maximum values (ii) first third quartiles, but do not deviation. To include these meta-analysis, methods have been developed from reported...
Perinatal depression is common, and treatment remains challenging. Depression has been reported to be associated with the abnormality of omega-3 polyunsaturated fatty acids (PUFAs). A profound decrease PUFAs in mother during pregnancy higher demand fetal development might precipitate occurrence depression. In this study, we examined efficacy PUFA monotherapy for pregnancy.From June 2004 2006, conducted an 8-week, double-blind, placebo-controlled trial comparing (3.4 g/d) placebo pregnant...
Eicosapentaenoic acid (EPA) and docosahexaenoic (DHA) can exert antidepressant, anti-inflammatory neuroprotective properties, but the exact molecular mechanism underlying their effects is still not fully understood. We conducted both in vitro clinical investigations to test which EPA or DHA metabolites are involved these anti-inflammatory, antidepressant effects. In vitro, we used human hippocampal progenitor cell line HPC0A07/03C, pre-treated cells with either DHA, followed by interleukin...
Gut microbiota alterations might affect the development of Alzheimer's disease (AD) through microbiota-derived metabolites. For example, Indoles via tryptophan metabolism prevented Aβ accumulation and Tau hyperphosphorylation, restored synaptic plasticity, then promoted cognitive behavioral ability APP/PS1 mice. The imbalanced compositions Indoles-producing bacteria with deficiency were found in male mice, but molecular mechanisms remained unclear. Our current study revealed that (including...
Large language models (LLMs) have been suggested to play a role in medical education and practice. However, the potential of their application psychiatric domain has not well-studied.
Parkinson's disease (PD) is intricately linked to abnormal gut microbiota, yet the specific microbiota influencing clinical outcomes remain poorly understood. Our study identified a deficiency in genus Blautia and reduction fecal short-chain fatty acid (SCFA) butyrate level PD patients compared healthy controls. The abundance of correlated with severity PD. Supplementation butyrate-producing bacterium B. producta demonstrated neuroprotective effects, attenuating neuroinflammation...
Omega-3 polyunsaturated fatty acids (PUFAs) may benefit migraine improvement, though prior studies are inconclusive. This study evaluated the effect of eicosapentaenoic acid (EPA) on episodic (EM) prevention. Seventy individuals with EM participated in a 12-week randomized, double-blind, placebo-controlled trial from March 2020 and May 2022. They were randomly assigned to either EPA (N = 35, 2 g fish oil 1.8 mg as stand-alone treatment daily), or placebo group soybean daily). Migraine...