A5101685762- Bipolar Disorder and Treatment
- Tryptophan and brain disorders
- Schizophrenia research and treatment
- Treatment of Major Depression
- Functional Brain Connectivity Studies
- Attention Deficit Hyperactivity Disorder
- Autism Spectrum Disorder Research
- Transcranial Magnetic Stimulation Studies
- Stress Responses and Cortisol
- Maternal Mental Health During Pregnancy and Postpartum
- Adolescent and Pediatric Healthcare
- Child and Adolescent Psychosocial and Emotional Development
- Mental Health Research Topics
- Genetics and Neurodevelopmental Disorders
- Suicide and Self-Harm Studies
- Dermatology and Skin Diseases
- Child Nutrition and Feeding Issues
- Electroconvulsive Therapy Studies
- Obsessive-Compulsive Spectrum Disorders
- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Advanced Neuroimaging Techniques and Applications
- Asthma and respiratory diseases
- Diet and metabolism studies
- Psychosomatic Disorders and Their Treatments
Taipei Veterans General Hospital
2016-2025
National Yang Ming Chiao Tung University
2016-2025
Harbin Huade University
2023-2024
Weatherford College
2023
National Defense Medical Center
2022-2023
National Yang Ming University Hospital
2009-2022
Bridge University
2017-2022
Cheng Hsin General Hospital
2019-2022
Tri-Service General Hospital Beitou Branch
2012-2022
Faculty (United Kingdom)
2020
The outbreak of severe acute respiratory syndrome (SARS) was unique because it highly concentrated in health care settings and a large number workers were infected. This study investigated stress reactions among 338 staff members hospital East Taiwan that discontinued emergency outpatient services to prevent possible nosocomial outbreak. Seventeen (5 percent) suffered from an disorder; stepwise multiple logistic regression analysis determined quarantine the most related factor. Sixty-six (20...
Theta-burst transcranial magnetic stimulation could modulate cortical excitability and has the potential to treat refractory depression. However, there been a lack of large randomized studies antidepressant efficacy different forms theta-burst stimulation, such as intermittent continuous stimulation. A sham-controlled study was conducted investigate compare among left-prefrontal right-prefrontal combination them in patients showing levels refractoriness. group 60 treatment-refractory with...
Increasing evidence supports reciprocal communication between the enteric and central nervous system in disease, termed 'gut-brain axis'. Recent findings suggest a connection IBD development of Parkinson's disease. The role dementia, another insidious neurodegenerative disorder, has not been explored.
Online gaming technology has developed rapidly within the past decade, and its related problems have received increasing attention. However, there are few studies on psychiatric symptoms associated with excessive use of online games. The aim this study is to investigate characteristics gamers, association between hours, social phobia, depression using an internet survey.An questionnaire was designed posted a popular game websites, inviting gamers participate survey. content included...
Large language models (LLMs) have been suggested to play a role in medical education and practice. However, the potential of their application psychiatric domain has not well-studied.
Abstract Background A great deal of evidence has shown that iron is an important component in cognitive, sensorimotor, and social-emotional development functioning, because the central nervous system processes highly dependent on iron-containing enzymes proteins. Deficiency early life may increase risk psychiatric morbidity. Methods Utilizing National Health Insurance Database from 1996 to 2008, children adolescents with a diagnosis IDA were identified compared age gender-matched controls...
People with major depressive disorder who fail to respond adequate trials of antidepressant treatment may harbour hidden bipolar disorder.We aimed compare the rates a change in diagnosis among people stratified responses antidepressants during an 8-year follow-up period.Information on individuals identified 2000 (cohort 2000, n = 1485) and 2003 2003, 2459) were collected from nationally representative cohort 1,000,000 health service users Taiwan. Participants responding well compared those...
Studies have suggested the association between autism spectrum disorder (ASD) and type 2 diabetes mellitus (DM)-related risk factors, such as obesity dyslipidemia. However, ASD DM remains unknown.We used Taiwan National Health Insurance Research Database for enrolling 6,122 adolescents young adults with 24,488 age- sex-matched control subjects 2002 2009 monitored them until end of 2011. Participants who developed during follow-up period were identified.Adolescents (hazard ratio [HR] 2.71...
Objective Research evidence has shown that bipolar disorder (BD) and unipolar depression (UD) are both related to inflammatory dysregulation, but few studies have compared the levels of cytokines between these two disorders. Methods Study subjects were age- gender-matched outpatients with BD or UD normal controls (NC). Severities mania symptoms assessed Montgomery–Åsberg Depression Rating Scale (MADRS) Young Mania (YMRS). Pro-inflammatory cytokines, including soluble interleukin-6 receptor...
Background: Attention deficit hyperactivity disorder (ADHD) and tic usually co‐occur in the same individuals, but underlying mechanisms remain unclear. Previous evidence has shown that a frequent coexistence of allergic diseases was noted patients with ADHD or disorder. We attempted to investigate possible link among ADHD, disorder, various diseases. Methods: Utilizing Taiwan National Health Insurance Research Database from 1996 2010, 5,811 alone, 1,816 349 dual diagnoses were identified...
Background Previous evidence has shown positive associations between post-traumatic stress disorder (PTSD) and hypertension, dyslipidaemia diabetes mellitus, which are all risk factors for stroke, but the role of PTSD in subsequent development stroke is still unknown. Aims To investigate temporal association stroke. Method Identified from Taiwan National Health Insurance Research Database, 5217 individuals aged 18 years, with no history 20 868 age- gender-matched controls were enrolled 2002...
Previous studies reported a high prevalence of depression among patients with autism spectrum disorder (ASD) and suggested relationship between ASD suicidality. However, whether independently increases the risk attempted suicide regardless has not been determined.Using Taiwan National Health Insurance Research Database, 5,618 adolescents aged 12-17 years young adults 18-29 (ICD-9-CM code: 299) 22,472 age- sex-matched controls were enrolled 2001 2009 followed to end 2011. Any attempt was...
Abstract Background Evidence suggests that major depressive disorder is related to neuroaxonal injury and neurofilament light chain (NfL) a biomarker of injury. In addition, proinflammatory cytokines have been reported be associated with depression Methods Forty patients 40 age- sex-matched healthy control participants were enrolled for the measurement NfL assessment executive function. General linear models used examine association between levels, cytokine Results Patients exhibited...
Abstract Background The benefits of low-dose ketamine for patients with treatment-resistant depression (TRD) and prominent suicidal ideation require further investigation. effects treatment refractoriness, the duration current depressive episode, number prior antidepressant failures on efficacy also clarification. Methods We recruited 84 outpatients TRD ideation—defined as a score ≥4 item 10 Montgomery–Åsberg Depression Rating Scale (MADRS)—and randomized them into 2 groups to receive 0.5...
Patients with schizophrenia treated clozapine often gain weight. This study evaluated the effects of dietary control and physical activity among obese inpatients being clozapine.Fifty-three clozapine-treated patients in a veterans hospital eastern Taiwan who had body mass index greater than 27 (weight divided by height meters squared) were taking randomly assigned to group 28 or 25. The was placed on diet that reduced calorie intake 200 300 kcal per day (to 1,300 1,500 for women 1,600 1,800...
Patients with ADHD have been suggested to increased risks of allergic diseases but without consistent results, and limited studies about the association between autoimmune were noted in literature.Utilizing Taiwan National Health Insurance Research Database, patients identified compared age- gender-matched controls (1:4).In all, 8,201 participants as having ADHD, an prevalence diseases, including asthma (odds ratio [OR] = 1.53), rhinitis (OR 1.59), atopic dermatitis urticaria 1.39), control...