Madeline Bender

ORCID: 0000-0002-4515-6805
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About
Contact & Profiles
Research Areas
  • Evolution and Genetic Dynamics
  • Gene Regulatory Network Analysis
  • Transgenic Plants and Applications
  • CRISPR and Genetic Engineering
  • Evolutionary Game Theory and Cooperation

Yale University
2020-2021

Abstract Directed evolution has been used for decades to engineer biological systems from the top-down. Generally, it applied at or below organismal level, by iteratively sampling mutational landscape in a guided search genetic variants of higher function. Above small number studies have attempted artificially select microbial communities and ecosystems, with uneven generally modest success. Our theoretical understanding artificial ecosystem selection is still limited, particularly large...

10.1101/2020.07.24.214775 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-07-25

10.1016/s0262-4079(20)31084-8 article EN The New Scientist 2020-06-01
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