A5059916191- Vitamin D Research Studies
- Vitamin C and Antioxidants Research
- Nutritional Studies and Diet
- Antioxidant Activity and Oxidative Stress
- Retinoids in leukemia and cellular processes
- Bone health and osteoporosis research
- Muscle metabolism and nutrition
- Effects and risks of endocrine disrupting chemicals
- Metabolomics and Mass Spectrometry Studies
- Fatty Acid Research and Health
- Mycotoxins in Agriculture and Food
- Birth, Development, and Health
- Diet and metabolism studies
- Clinical Laboratory Practices and Quality Control
- Pancreatic function and diabetes
- Adrenal Hormones and Disorders
- Carcinogens and Genotoxicity Assessment
- Iron Metabolism and Disorders
- Neuropeptides and Animal Physiology
- Estrogen and related hormone effects
- Meta-analysis and systematic reviews
- Retinal Diseases and Treatments
- Hormonal and reproductive studies
- Folate and B Vitamins Research
- Eating Disorders and Behaviors
Centers for Disease Control and Prevention
2010-2023
National Center for Environmental Health
2010-2023
Hyattsville Community Development Corporation
2019-2020
Center for Environmental Health
2018
Material Measurement Laboratory
2013
United States Department of Commerce
2013
Jagiellonian University
2007-2009
Center for Children
2007-2009
Southwest Research Institute
2007-2009
Office of Dietary Supplements
2008-2009
Vitamin D is important for bone health; in 2014 it was the fifth most commonly ordered laboratory test among Medicare Part B payments.The aim of this study to describe vitamin status US population 2011-2014 and trends from 2003 2014.We used serum 25-hydroxyvitamin data NHANES (n = 16,180), estimated prevalence at risk deficiency (<30 nmol/L) or inadequacy (30-49 by age, sex, race Hispanic origin, dietary intake D. We also present between 2014.In 2011-2014, percentage aged ≥1 y 5.0% (95% CI:...
During January-June 2004, an aflatoxicosis outbreak in eastern Kenya resulted 317 cases and 125 deaths. We conducted a case-control study to identify risk factors for contamination of implicated maize and, the first time, quantitated biomarkers associated with acute aflatoxicosis.We administered questionnaires regarding storage consumption obtained blood samples from participants.We recruited 40 case-patients 80 randomly selected controls participate this study.We analyzed total aflatoxins...
Abstract Vitamin D is an essential nutrient for bone health and may influence the risks of respiratory illness, adverse pregnancy outcomes, chronic diseases adulthood. Because many countries have a relatively low supply foods rich in vitamin inadequate exposure to natural ultraviolet B (UVB) radiation from sunlight, important proportion global population at risk deficiency. There general agreement that minimum serum/plasma 25‐hydroxyvitamin concentration (25(OH)D) protects against...
Abstract The Age‐Related Eye Disease Study (AREDS), sponsored by the National Institute, was designed to study natural history and risk factors of age‐related macular degeneration (AMD) cataract, evaluate effect high doses antioxidants zinc on eye disease progression. AMD cataract are leading causes visual impairment blindness in U.S., with frequency both diseases increasing dramatically after age 65. Participants were randomly chosen receive antioxidant or placebo tablets. Blood drawn...
A reverse J-shaped association between serum 25-hydroxyvitamin D (25[OH]D) concentration and all-cause mortality was suggested in a 9-year follow-up (1991-2000) analysis of the Third National Health Nutrition Examination Survey (NHANES III, 1988-1994).Our objective to repeat analyses with 6 years additional evaluate whether persists through 15 follow-up.The study included 099 participants aged ≥ 20 3784 deaths.Relative risk (RR) death from all causes adjusted for age, sex, race/ethnicity,...
The National Institute of Standards and Technology (NIST), in collaboration with the Institutes Health's Office Dietary Supplements (NIH-ODS), has developed a Standard Reference Material (SRM) for determination 25-hydroxyvitamin D [25(OH)D] serum. SRM 972 Vitamin Human Serum consists four serum pools different levels vitamin metabolites certified reference values 25(OH)D2, 25(OH)D3, 3-epi-25(OH)D3. Value assignment this was accomplished using combination three isotope-dilution mass...
The National Institute of Standards and Technology (NIST), in collaboration with the Institutes Health (NIH), has developed a Standard Reference Material (SRM) to support technology development metabolomics research. SRM 1950 Metabolites Human Plasma is intended have metabolite concentrations that are representative those found adult human plasma. plasma used preparation was collected from both male female donors, donor ethnicity targets were selected based upon ethnic makeup U.S....
Abstract Essential to the conduct of epidemiologic studies examining aflatoxin exposure and risk heptocellular carcinoma, impaired growth, acute toxicity has been development quantitative biomarkers aflatoxins, particularly B1. In this study, identical serum sample sets were analyzed for aflatoxin-albumin adducts by ELISA, high-performance liquid chromatography (HPLC) with fluorescence detection (HPLC-f), HPLC isotope dilution mass spectrometry (IDMS). The human samples from an aflatoxicosis...
The goals were to determine the prevalence of vitamin D deficiency among minority children in a southern US city, examine differences serum 25-hydroxyvitamin levels between non-Hispanic black and Hispanic children, dietary sources D.Low-income, (N = 290; mean age: 2.5 +/- 1.2 years) recruited during well-child clinic visits. Serum calcium measured information was assessed.The D(3) level 26.2 7.6 ng/mL, whereas D(2) not detected. Overall, 22.3% had deficient (< or =20 ng/mL), 73.6%...
Environmental conditions during sample processing, shipping, and storage are often suboptimal, particularly in less developed countries. We used samples from US volunteers to investigate the effects of delayed whole blood (WB) processing freezing serum on selected nutritional indicators.WB tubes (n = 35) were either stored at 32 degrees C for up 3 days before separation or centrifuged within 2 h collection; 11 14 simulate shipping. assessed analyte stability by comparing results with data...
Abstract Background We compared serum vitamin C (VIC) status of the adult (≥20 y) US population in National Health and Nutrition Examination Survey (NHANES) 2017–2018 with combined data from 2003–2004 2005–2006. Methods VIC was measured using HPLC electrochemical detection. Mean were stratified by age, sex, race/Hispanic origin, income, body mass index, dietary intake, supplement use, smoking status. Prevalence deficiency (&lt;11.4 μmol/L) calculated. Results In NHANES 2017–2018, mean 8...
Abstract A method for quantitative analysis of aflatoxin B1‐lysine adduct (B1‐Lys) in serum by liquid chromatography using tandem mass spectrometry (LC/MS/MS) is presented. The protein a 250‐µL sample was digested the presence stable‐isotope internal standard during 4‐h incubation at 37°C with Pronase™. B1‐Lys and were extracted mixed‐mode solid‐phase extraction cartridges eluted 2% formic acid methanol. Following evaporation reconstitution, extracts injected onto Luna C‐18(2) column step...