A5101532186- Cancer, Hypoxia, and Metabolism
- High Altitude and Hypoxia
- Hematological disorders and diagnostics
- Congenital Diaphragmatic Hernia Studies
- Tracheal and airway disorders
- Esophageal and GI Pathology
- Congenital Anomalies and Fetal Surgery
- Renin-Angiotensin System Studies
- Intraoperative Neuromonitoring and Anesthetic Effects
- Nutrition, Genetics, and Disease
- Glaucoma and retinal disorders
- Amoebic Infections and Treatments
- Retinal and Optic Conditions
- Parasitic infections in humans and animals
- Diet and metabolism studies
- Lipoproteins and Cardiovascular Health
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Heme Oxygenase-1 and Carbon Monoxide
- Autophagy in Disease and Therapy
- Airway Management and Intubation Techniques
- Cleft Lip and Palate Research
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Head and Neck Surgical Oncology
- Hormonal Regulation and Hypertension
Qinghai University
2017-2021
Qinghai University Affiliated Hospital
2014-2021
Beijing University of Chinese Medicine
2015-2018
Air Force Medical University
2013-2018
Qilu Hospital of Shandong University
2014
Second Hospital of Shanxi Medical University
2009
Chinese medicine xiangshaliujunzi decoction (XSLJZD) plays a key role in treating functional dyspepsia (FD), common clinical gastrointestinal disorder. However, the mechanism of this disease is unclear. Brain–gut axis regulates food intake behaviour, and regulatory mediated by neuropeptides. impairment neuropeptide alteration may be pathological mechanisms FD, brain–gut regulation influence action medicine. In our experiment, effect XSLJZD on FD was evaluated terms intake, sucrose preference...
Abstract Chronic mountain sickness (CMS) is a progressive incapacitating syndrome induced by lifelong exposure to hypoxia. In the present study, proteomic analysis was used identify differentially expressed proteins (DEPs) and then evaluate potential plasma biomarkers between CMS non-CMS groups. A total of 145 DEPs were detected in Han Chinese people who live plateau (CMS-HPu), among which 89 significantly up-regulated 56 down-regulated. GO enrichment showed that various biological processes...
Excessive erythrocytosis (EE) is a characteristic of chronic mountain sickness (CMS). Currently, the pathogenesis CMS remains unclear. This study was intended to investigate role EPAS1 in proliferation erythroblasts CMS. Changes HIF-1α and EPAS1/HIF-2α bone marrow 21 patients with 14 control subjects residing at same altitudes were determined by RT-qPCR western blotting. We also developed lentiviral vector, Lv-EPAS1/sh-EPAS1, over-express/silence K562 cells. Cells cycle detected flow...
BACKGROUND Chronic mountain sickness (CMS) has a higher incidence in the plateau region. The one of its principal characters is excessive erythrocytosis. PI3K-Akt pathway plays an important role process erythropoiesis, and could downregulate apoptosis by regulating apoptosis-related molecules. In this paper, we explored change erythroblasts effect signal on CMS. MATERIAL AND METHODS A total 22 CMS 20 non-CMS participants were involved study. Bone marrow mononuclear cells cultured treated...
The traditional Chinese medicine (TCM) decoction Si-Ni-San (SNS) has been utilised for millennia to improve physiological coordination of the functions liver and spleen, which are regarded as main pathological organs central fatigue in TCM. This study evaluates effect a modified SNS (MSNS) formula on rats explores molecular changes associated with hippocampal mitochondrial biogenesis. Central was induced through 21-day sleep deprivation protocol. We assessed MSNS’s effects behaviour, blood...
Background : Echinococcosis is a chronic consumptive liver disease. Little research has been carried out on the nutritional status of infected patients, though diseases are often associated with malnutrition. Our study investigated four different nutrition screening tools, to assess risks hospitalized patients echinococcosis. Methods Nutritional Risk Screening 2002 (NRS 2002), Short Form Mini Assessment (MNA-SF), Malnutrition Universal Tool (MUST), and Nutrition Index (NRI) were used 164...
Objective: To compare the blood flow around optic disc and related factors in patients with acute chronic non-arteritic anterior ischemic neuropathy (NAION) healthy volunteers small cups under same anatomical structure. Methods: This was a prospective case-control study. NAION unilateral onset of phase were included study conducted at Department Ophthalmology Peking Union Medical College Hospital between February 2017 September 2018. Patients course ≤ 3 months categorized NAION, those >3...
Globally, coronary heart disease (CHD) is a primary cause of morbidity leading to disabilities and mortality. Modern clinical practice adopts several pharmacological methods treat CHD. Angina pectoris refers sever chest pain due CHD, it has profound impact on the wellbeing patients. Moreover, angina crucial prognosis predictor. The aim current study evaluate effectiveness safeness using combined rosuvastatin atorvastatin CHD patients.A systematic literature search for articles will be...
This study aimed to report the case of a patient diagnosed with pulmonary sequestration accompanied by an intermittent haematemesis as initial and life-threatening symptom. Emergent surgical intervention finally confirmed rare direct fistula formation between arterial blood supply oesophagus, which led upper gastrointestinal haemorrhage. To our knowledge, this is first reported kind formation.
Objective To evaluate the effects of oropharyngeal topical anesthesia with tetracaine spray (0.1％) on discomfort and success rate insertion stomach tube after orthognathic surgery.Methods Totals 80 patients treated bimaxillary surgery were randomly assigned into control group (n =40) test =40).Stomach tubes inserted stomachs a semirecumbent position through nasal at day surgery.Traditional methods inserting applied in group,while given 0.1％ to before inserted.The operating time primary...