Zhouke Tan

ORCID: 0000-0002-4532-3474
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About
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Research Areas
  • Acute Kidney Injury Research
  • Chronic Kidney Disease and Diabetes
  • Sepsis Diagnosis and Treatment
  • Herbal Medicine Research Studies
  • Case Reports on Hematomas
  • Healthcare and Venom Research
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Immune Response and Inflammation
  • Bone fractures and treatments
  • Medicinal Plants and Bioactive Compounds
  • Health Systems, Economic Evaluations, Quality of Life
  • Musculoskeletal Disorders and Rehabilitation
  • Platelet Disorders and Treatments
  • Healthcare Systems and Reforms
  • Cell Adhesion Molecules Research
  • Gout, Hyperuricemia, Uric Acid
  • Endometriosis Research and Treatment
  • Congenital limb and hand anomalies

Zunyi Medical University
2022-2025

Sichuan University
2022

West China Hospital of Sichuan University
2022

Chongqing Academy of Chinese Materia Medica
1997

Institute of Chinese Materia Medica
1997

Sepsis is a systemic inflammatory response to infection, where sepsis-associated acute kidney injury (AKI) common morbid disease with high morbidity and mortality, however at present no effective therapy exists. Increasing evidence have shown that mitochondrial damage are important initiating factors in pathogenesis of septic AKI. Natural flavonoid pectolinarigenin exerted anti-inflammatory properties previous studies, while its role AKI remains unknown. In the study, administration...

10.1016/j.biopha.2023.114286 article EN cc-by-nc-nd Biomedicine & Pharmacotherapy 2023-01-26

Natural flavonoid pectolinarigenin (PEC) was reported to alleviate tubulointerstitial fibrosis of unilateral ureteral obstruction (UUO) mice in our previous study. To further investigate nephroprotective effects PEC hyperuricemic nephropathy (HN), adenine and potassium oxonate induced HN uric acid-treated mouse kidney epithelial (TCMK-1) cells were employed the As a result, significantly lowered serum acid level restored hyperuricemia-related injury mice. Meanwhile, alleviated inflammation,...

10.3389/fphar.2021.792139 article EN cc-by Frontiers in Pharmacology 2022-01-27

Chronic kidney disease (CKD) is a global health challenge with diverse etiologies. However, research on the incidence trends of CKD attributable to specific causes remains limited, and mortality rates vary across regions. This study aims identify patterns temporal incidence, providing valuable information for development targeted prevention strategies interventions. data from 2021 Global Burden Disease Study (1990-2021) were analyzed by sex, region, country, cause, Socio-demographic Index...

10.1186/s41182-025-00703-x article EN cc-by Tropical Medicine and Health 2025-02-21

<title>Abstract</title> Background Congenital musculoskeletal and limb anomalies represent a rare complex condition globally, with multifactorial etiology. Limited research has been conducted on the incidence trends of these anomalies. This study aims to investigate patterns temporal congenital Methods Detailed data from 1990 2021 were sourced Global Burden Disease Study, stratified by sex, region, country, integrated Socio-demographic Index (SDI). To quantify burden anomalies, we utilized...

10.21203/rs.3.rs-6063028/v1 preprint EN cc-by Research Square (Research Square) 2025-03-03
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