A5047923381- Cancer Research and Treatments
- Plant Water Relations and Carbon Dynamics
- Polar Research and Ecology
- Genomics and Phylogenetic Studies
- Biocrusts and Microbial Ecology
- Photosynthetic Processes and Mechanisms
- Lichen and fungal ecology
- Plant Stress Responses and Tolerance
- Microbial Community Ecology and Physiology
- Liver physiology and pathology
- Cancer Mechanisms and Therapy
- Plant Genetic and Mutation Studies
- Bacteriophages and microbial interactions
- Protein Hydrolysis and Bioactive Peptides
- Aluminum toxicity and tolerance in plants and animals
- Food Quality and Safety Studies
- Phytoestrogen effects and research
- Turfgrass Adaptation and Management
- Digestive system and related health
- Diet, Metabolism, and Disease
- Microbial Metabolites in Food Biotechnology
- Arsenic contamination and mitigation
- RNA Research and Splicing
- Tuberculosis Research and Epidemiology
- Polysaccharides and Plant Cell Walls
Universidad de La Frontera
2008-2023
Universidad Autónoma de Chile
2016-2023
Adolfo Ibáñez University
2010
Silicon (Si) has been well documented to alleviate aluminum (Al) toxicity in vascular plants. However, the mechanisms underlying these responses remain poorly understood. Here, we assessed effect of Si on modulation Si/Al uptake and antioxidant performance ryegrass plants hydroponically cultivated with Al (0 0.2 mM) combination (0, 0.5, 2.0 mM). Exposure significantly increased concentration, mainly roots, a consequent reduction root growth. applied culture media steadily diminished...
Studies on the low-abundance transcriptome are of paramount importance for identifying intimate mechanisms tumor progression that can lead to novel therapies. The aim present study was identify markers and targetable genes pathways in advanced human gastric cancer through analyses transcriptome. procedure involved an initial subtractive hybridization step, followed by global gene expression analysis using microarrays. We observed profound differences, both at single ontology levels, between...
Tuberculosis (TB) is one of the leading causes human deaths worldwide caused by infectious diseases. TB infection Mycobacterium tuberculosis can occur in lungs, causing pulmonary (PTB), or any other organ body, resulting extrapulmonary (EPTB). There no consensus on genetic determinants this pathogen that may contribute to EPTB. In study, we constructed M. pangenome and used it as a tool seek genomic signatures associated with clinical presentation based its accessory genome differences. The...
In colorectal carcinoma patients, distant metastatic disease is present at initial diagnosis in nearly 25% of them. The majority patients with have incurable disease; therefore, new therapies are needed. Agents derived from medicinal plants already demonstrated therapeutic activities human cancer cells. Antartina an antitumor agent isolated Deschampsia antarctica Desv. This study aimed to evaluate the properties models. We used and murine cell lines for investigating proliferation,...
Abstract Background Filmy-ferns (Hymenophyllaceae) are poikilohydric, homoiochlorophyllous desiccation-tolerant (DT) epiphytes. They can colonize lower and upper canopy environments of humid forest. desiccate rapidly (hours), contrasting with DT angiosperms (days/weeks). It has been proposed that desiccation tolerance in filmy-ferns would be associated mainly constitutive features rather than induced responses during dehydration. However, we hypothesize the inter-specific differences...
Hymenoglossum cruentum (Hymenophyllaceae) is a poikilohydric, homoiochlorophyllous desiccation-tolerant (DT) epiphyte fern. It can undergo fast and frequent dehydration-rehydration cycles. This fern highly abundant at high-humidity/low-light microenvironments within the canopy, although rapid changes in humidity light intensity are frequent. The objective of this research to identify genes associated desiccation-rehydration cycle transcriptome H. better understand genetic dynamics behind its...
Abstract Deschampsia antarctica Desv. (Poaceae) grows in coastal habitats the Maritime Antarctic where it is often exposed to sea spray. Salt crystals have been observed on surface of leaves plants treated with high NaCl. We investigated if D. a salt tolerant species that allows sodium ions diffuse into root overly sensitive (SOS) system extrudes Na + from cells and facilitates its movement through xylem up leaves. Leaf epidermis, physiological parameters transporters NaCl were studied over...
Deschampsia antarctica Desv. (Poaceae) is the only native Gramineae found in Antarctic, where it restricted to Antarctic Peninsula and its offshore islands. Its ability survive harsh climate has attracted interest of scientists searching for genes associated with freezing tolerance (Alberdi et al. 2002). For continuing research purposes would be better if plants did not have collected from field, but could propagated effectively provide necessary experimental material D. normally reproduces...
The current study isolated and characterized the Lip3F9 polypeptide sequence of Deschampsia antarctica Desv. (GeneBank Accession Number JX846628), which was found to be comprised 291 base pairs was, moreover, expressed in Pichia pastoris X-33 cells. enzyme secreted after 24 h P. culture incubation through induction with methanol. protein showed maximum lipase activity (35 U/L) an optimal temperature 37 °C. lipase-expressed lost 50% its specific at 25 °C, a behavior characteristic...
Cancer is the second leading cause of death in world and colorectal cancer only that has shown a sustained increase mortality last decade. In search for new chemotherapeutic agents against cancer, extremophilic microorganisms have to be potential source obtain molecules natural origin with selective cytotoxic action towards cells. this work we analyzed ability collection Antarctic soil bacteria, isolated on Collins Glacier from rhizosphere Deschampsia antarctica Desv plant, secrete capable...
Antarctic soils are considered young soils; therefore, the microbiota associated with vascular plants play a critical role in their productivity. In this research, we compared from three different soil conditions using 16S rRNA and internal transcribed spacer gene amplicon approach for bacterial fungal communities.
<p>Information about experimental procedure to obtain Antartina</p>
<p>Preconditioning of DCs derived from (A) cancer patients and healthy donors, (B) mice using10 μg/ml Antartina{trade mark, serif} enhances the expression activation markers</p>
<p>Toxicology analysis. Liver transaminases aspartate aminotransferase (AST) and alanine (ALT) were measured after Antartina{trade mark, serif} treatment H&E stained tissues from BALB/c mice untreated (n= 5) or treated with 5 mg/kg (n=5) 50 of serif}</p>
<p>In vivo efficacy of Tricin and 5-FU</p>
<div>Abstract<p>In colorectal carcinoma patients, distant metastatic disease is present at initial diagnosis in nearly 25% of them. The majority patients with have incurable disease; therefore, new therapies are needed. Agents derived from medicinal plants already demonstrated therapeutic activities human cancer cells. Antartina an antitumor agent isolated <i>Deschampsia antarctica</i> Desv. This study aimed to evaluate the properties models. We used and murine cell...
<div>Abstract<p>In colorectal carcinoma patients, distant metastatic disease is present at initial diagnosis in nearly 25% of them. The majority patients with have incurable disease; therefore, new therapies are needed. Agents derived from medicinal plants already demonstrated therapeutic activities human cancer cells. Antartina an antitumor agent isolated <i>Deschampsia antarctica</i> Desv. This study aimed to evaluate the properties models. We used and murine cell...
<p>Preconditioning of DCs derived from (A) cancer patients and healthy donors, (B) mice using10 μg/ml Antartina{trade mark, serif} enhances the expression activation markers</p>