- Veterinary Oncology Research
- Infectious Diseases and Mycology
- Virus-based gene therapy research
- Mast cells and histamine
- Microbial Inactivation Methods
- Hematopoietic Stem Cell Transplantation
- Cutaneous lymphoproliferative disorders research
- Salivary Gland Tumors Diagnosis and Treatment
- Genomic variations and chromosomal abnormalities
- Herpesvirus Infections and Treatments
- Salivary Gland Disorders and Functions
- T-cell and Retrovirus Studies
- Angiogenesis and VEGF in Cancer
- Cancer and Skin Lesions
- Oral and Maxillofacial Pathology
- Microbial infections and disease research
- Oral Health Pathology and Treatment
- Animal Genetics and Reproduction
Universidade Federal de Minas Gerais
2024-2025
Universidade de São Paulo
2024
Universidade Vila Velha
2020-2021
Vascular endothelial growth factor (VEGF) is an important regulator of angiogenesis and has been identified as autocrine for neoplastic cells several tumors. The aim this study was to evaluate VEGF expression in canine mast cell tumors their respective lymph node metastases. For purpose, 28 patients with confirmed regional metastasis were selected. samples submitted analysis immunohistochemistry. expressed 14/28 (50%) 35.7% primary MCTs (10/28), only 14.3% both the tumor its (4/28), fair...
Objectives The aim of this study was to establish the safety and efficacy a novel multidrug lomustine-based chemotherapeutic protocol for cats with high-grade multicentric or mediastinal lymphoma, in an area endemic feline leukemia virus (FeLV). Methods This prospective included owned cats, diagnosed (cytologically) lymphoma treated LOPH (lomustine, vincristine [Oncovin; Antibióticos do Brasil], prednisolone hydroxydaunorubicin [doxorubicin]) protocol. A complete blood count performed before...
Feline histiocytic diseases are uncommon and rarely reported. progressive histiocytosis (FPH) is the most common disease in cats, predominantly affecting middle-aged animals. The presentation cutaneous form with solitary or multiple nodules. A female, mixed-breed 6-year-old cat was presented a 9-month history of nodule nasal planum diagnosed by histopathology proliferation. At time diagnosis, new nodules were discovered on lower lip, digit, two lesions tail region, largest measuring 1.5 cm....
Cutaneous lymphoma is histologically classified in epitheliotropic and non-epitheliotropic, the first showing higher incidence dogs, second, cats. Non-epitheliotropic presents lymphocyte aggregates dermis subcutaneous tissue, however cutaneous annexes are not infiltrated. It usually more aggressive than lymphomas. The aim of this study was to report a case non-epitheliotropic 9-year-old, female, English Bulldog presented with non-ulcerated skin nodules adhered deep tissues. Microscopic...
Background: Tyrosine kinase inhibitors (TKIs) may sensitize neoplasms to conventional antineoplastic agents, however such studies are scarse in the veterinary literature and there is no vivo study about this subject. Although recommend consensual use of masitinib for unresectable or metastatic MCTs, potential tumour sensitization chemotherapeutic agents exerted by drug poorly explored medicine. The objective paper was report, first time, 2 canine mast cell tumours (MCTs) lomustine, with...
Retroviruses are among the leading causes of death in domestic cats. associate with host cell a persistent and permanent way, to diverse clinical conditions. The feline leukemia virus (FeLV) is most pathogenic retrovirus potential cause both degenerative diseases immunosuppression, as well proliferative diseases, its association may lead direct oncogenic effect. immunodeficiency (FIV), turn, can classic syndrome, usually has chronic, less aggressive course no use vaccines control measures...