Herein we report a polymerization-induced self-assembly (PISA) process with ring-opening metathesis polymerization (ROMP). We utilize peptide-based norbornenyl monomer as hydrophobic unit to provide range of nanostructures at room temperature yet high solids concentrations 20 wt % in combination an oligoethylene glycol based monomer. Evaluation the polymerizations under mild conditions highlight that good control is maintained along conversion greater than 99%, indicating living unaffected...

In this paper, we describe the use of liquid cell transmission electron microscopy (LCTEM) for inducing and imaging formation spherical micelles from amphiphilic block copolymers. Within irradiated region cell, diblock copolymers were produced which self-assembled, yielding a targeted micellar phase via polymerization-induced self-assembly (PISA). Critically, demonstrate that nanoparticle can be visualized in situ presence excess monomer, growth occurs to yield sizes morphologies consistent...

Competition among individual plants is usually asymmetric, i.e. larger are able to obtain a disproportionate share of the resources (for their relative size) and suppress growth smaller individuals. There evidence that asymmetry competition primarily due shading, but there very little information about symmetry below ground. We grew Kochia scoparia individuals singly in pairs containers for 54 d with dividers above ground so could occur only Initial size differences were generated by 10-d...

Reversible addition-fragmentation chain transfer copolymerization of dimethylaminoethyl acrylate (DMAEA) and methyl (MA) their methacrylate counterparts (MMA) has been performed with good control over molecular weight polydispersity. A screening in composition copolymers from 0 to 75% MA (or MMA). The behavior these pH temperature-sensitive studied aqueous solution by measuring the cloud point (CP) acid dissociation constants (pKa). higher incorporation hydrophobic monomer copolymer resulted...

We report aqueous-phase Ring-Opening Metathesis Polymerization-Induced Self-Assembly (ROMPISA) for forming well-defined micellar polymer nanoparticles at room temperature and high solids concentration (20 w/w%). This is achieved with a new polymerization initiator, in the form of water-soluble cationic Hoveyda-Grubbs second generation catalyst. reaction was used water to produce diblock copolymers from norbornenyl monomers, which then self-assemble into myriad nanostructure morphologies...

Polymer self-assembly in solution is a simple strategy for the preparation of elegant yet complex nanomaterials. However, exhaustive synthesis copolymer synthons often required to access specific assemblies. In this work we show that blending just two diblock copolymers with identical block lengths but varying hydrophobic monomer incorporations can be used range assemblies intermediate composition. Indeed, nanostructures produced from are those formed directly synthesized same This new...

Abstract Open‐to‐air aqueous‐phase ring‐opening metathesis polymerization‐induced self‐assembly (ROMPISA) is reported for forming well‐defined peptide polymer nanoparticles at room temperature and with high solids concentrations (10 w/w%). For these materials, ROMPISA shown to provide control over molecular weight conversion while open‐to‐air. Moreover, can spontaneously rearrange into larger aggregate scaffolds in the presence of proteolytic enzyme, thermolysin. This work demonstrates...

A series of pH sensitive amphiphilic diblock copolymers where the associating block is a copolymer have been synthesized. Their behavior has explored by range analytical techniques and nanostructures formed are highly to both composition.

We report the one-pot aqueous phase synthesis of cisplatin drug loaded micellar nanoparticles using Ring-Opening Metathesis Polymerization-Induced Self-Assembly (ROMPISA).

The concept of micelle blending is explored as a new route to afford well-defined polymer nanostructures.

The chain density of polymer micelles, dictated by their aggregation number (Nagg), is an often overlooked parameter that governs the macroscopic behavior responsive assemblies. Using a combination variable-temperature light scattering, turbidimetry, and microcalorimetry experiments, cloud point thermal collapse micellar poly(N-isopropylacrylamide) (pNIPAM) corona chains at lower temperatures than were found to be largely independent micelle's Nagg. By controlling core composition, degree...

In this paper, experiment and simulation were combined to provide a view of the molecular rearrangements underlying equilibrium nonequilibrium transitions occurring in stimuli-responsive block copolymer amphiphile self-assemblies. Three amphiphiles prepared, each consisting hydrophilic peptide brush, responsive proteolytic enzymes, containing one three possible hydrophobic blocks: (1) poly(ethyl acrylate), (2) poly(styrene), or (3) poly(lauryl acrylate). When assembled, they generate...

In this paper, we show the rapid generation of phase diagrams for block copolymer amphiphiles. We demonstrate high-throughput approach two separate types amphiphilic copolymers: One type consisting poly(ethylene glycol)-b-poly(2-hydroxypropyl methacrylate) and other poly(2-(dimethylamino)ethyl methacrylate)-b-poly(2-hydroxypropyl methacrylate), where each was prepared by systematically varying degree polymerization hydrophobic block. These were synthesized in 96-well plates using...

Implicit in most flashbulb memory research are three assumptions: that major news events will be important for almost everyone the chosen sample, people's ratings of quality reliable and a detailed recollection personal circumstances implies vivid memory. Using two general population surveys Great Britain (total N = 3160), we examine each these assumptions have recently been used studies: Margaret Thatcher's resignation as Prime Minister Hillsborough football disaster. The results emphasize...

Polymerization reactions triggered by stimuli play a pivotal role in materials science, with applications ranging from lithography to biomedicine adaptive materials. However, the development of chemically triggered, stimuli-responsive systems that can confer spatial and temporal control on polymerization remains challenge. Herein, chemical-stimuli-induced based liquid crystal (LC) printhead is presented. The LC responds local chemical stimulus at its aqueous interface, resulting ejection...

The p<italic>K</italic>_aof a polyelectrolyte has been determined experimentally by potentiometric titration and computed using Molecular Dynamics (MD) constant pH (CpH) methodology, which allows the each titratable site along polymer backbone.

Abstract When people remember together, what one person says can affect others report. The size of this effect is dependent on characteristics the and how they express their beliefs. power relationship among affects much social cognition, including memory conformity effect. However, some research has shown conform more to high individuals shows opposite. proposed identified we believe an important difference in these studies type that was manipulated: evaluation versus managerial power. will...

Reliable and valid measurement of trust in science scientists is important. Assessing levels such important determining attitudes predicting behaviours response to medical scientific interventions targeted at managing public crises. However, a complex phenomenon that has be understood relation both distrust mistrust. The Trust Science Scientists Scale been adopted with increasing frequency large-scale health research. Detailed psychometric evaluation the scale overdue makes meaningful...

The nondestructive, covalent reactivity of single-layer graphene oxide (SLGO) and hydrazine-reduced (rGO) in relation to its 3-dimensional geometry has been previously considered for various chemical reactions. However, the capability modified system undergo additional chemistry is now demonstrated through an in-situ polycondensation reaction resulting linear or hyperbranched condensed polymers [e.g., polyureas, polyurethanes, poly(urea–urethane)-bonded graphenes]. use aliphatic...

Abstract. Floods are the product of complex interactions processes including rainfall, soil moisture, and watershed morphology. Conventional flood frequency analysis (FFA) methods such as design storms discharge-based statistical offer few insights into process how they shape probability distributions floods. Understanding projecting in conditions nonstationary hydroclimate land use requires deeper understanding these processes, some or all which may be changing ways that will undersampled...

Front Cover: Ring-opening metathesis polymerization-induced self-assembly (ROMPISA) is a robust methodology for the formation of myriad responsive nanostructures in one pot, air. In article number 1800467 by Nathan C. Gianneschi and colleagues, framboidal vesicles water via polymerization peptide-functionalized monomers reported.