A5103144938- Shoulder Injury and Treatment
- Medical research and treatments
- Shoulder and Clavicle Injuries
- Sports injuries and prevention
- Anesthesia and Neurotoxicity Research
- Pediatric Pain Management Techniques
- Anesthesia and Sedative Agents
- Chronic Obstructive Pulmonary Disease (COPD) Research
University of Michigan
2012-2021
Abstract Full‐thickness tears to the rotator cuff can cause severe pain and disability. Untreated progress in size are associated with muscle atrophy an infiltration of fat area, a condition known as “fatty degeneration.” To improve treatment tears, greater understanding changes contractile properties fibers molecular regulation fatty degeneration is essential. Using rat model injury, we measured force generating capacity individual determined fiber type distribution that develop after full...
Rotator cuff tears are a common source of shoulder pain and disability. Even after surgical repair, some patients continue to have reduced function progression fatty degeneration. Because with chronic often experience muscle shortening, it is possible that repairing the tendon its anatomic footprint induces stretch-induced injury could contribute failures repair perhaps ongoing pain.We hypothesized that, compared acutely torn repaired muscles, stretch required chronically would result in...
Objectives: Rotator cuff tears are a common source of shoulder pain and disability. Even after surgical repair these tears, many patients continue to have reduced function progression intramuscular fatty degeneration. Previous work in sheep model demonstrated that slow, progressive lengthening chronically torn muscles followed by the tendon reversed degeneration improved muscle function. As with chronic often experience shortening fibers, it is possible repairing its original anatomical...
Davis, Max E. BA1; Stafford, Patrick L. BS1; Bradley, Joshua R. Bedi, Asheesh MD1; Mendias, Christopher PhD, ATC1 Author Information
Rotator cuff tears often cause pain and decreased mobility, are associated with atrophy of muscle fibers, fibrosis accumulation fat in the muscle, collectively referred to as “fatty atrophy.” Previous studies have demonstrated that surgical repair torn muscles does not reduce fatty atrophy. As molecular etiology remains unknown, gaining greater insight into mechanisms lead development will improve treatment rotator tears. Using a rat model, we measured single fiber contractility, type...