A5011362240- Cystic Fibrosis Research Advances
- Medication Adherence and Compliance
- Health Systems, Economic Evaluations, Quality of Life
- Inhalation and Respiratory Drug Delivery
- Adolescent and Pediatric Healthcare
- Mobile Health and mHealth Applications
- Pharmaceutical studies and practices
- Pediatric health and respiratory diseases
- Simulation Techniques and Applications
- Health and Medical Studies
- Retirement, Disability, and Employment
- Asthma and respiratory diseases
- Telemedicine and Telehealth Implementation
- Impact of Technology on Adolescents
- Motivation and Self-Concept in Sports
- Assembly Line Balancing Optimization
- Delphi Technique in Research
- Economic and Environmental Valuation
- Business Process Modeling and Analysis
- Behavioral Health and Interventions
- Scheduling and Timetabling Solutions
- Vaccine Coverage and Hesitancy
- Geriatric Care and Nursing Homes
- Social and Demographic Issues in Germany
- demographic modeling and climate adaptation
Northern General Hospital
2015-2024
Sheffield Teaching Hospitals NHS Foundation Trust
2019-2024
Sheffield Hallam University
2020
Recurrent pulmonary exacerbations lead to progressive lung damage in cystic fibrosis (CF). Inhaled medications (mucoactive agents and antibiotics) help prevent exacerbations, but objectively measured adherence is low. We investigated whether a multi-component (complex) self-management intervention support would reduce exacerbation rates over 12 months.Between October 2017 May 2018, adults with CF (aged ≥16 years; 19 UK centres) were randomised the (data-logging nebulisers, digital platform...
Adherence to nebulizer treatment in adults with Cystic Fibrosis (CF) is poor, and interventions are needed. This research aimed identify the factors affecting adherence using Theoretical Domains Framework (TDF) compare these for participants different levels of adherence.
Cystic fibrosis (CF) is a life-limiting genetic condition in which daily therapies to maintain lung health are critical, yet treatment adherence low. Previous interventions increase have been largely unsuccessful and this likely due lack of focus on behavioural evidence theory alongside input from people with CF. This intervention based digital platform that collects displays objective nebuliser data. The purpose paper identify the specific components an treatments adults CF reducing effort burden.
Preventative medication reduces hospitalisations in people with cystic fibrosis (PWCF) but adherence is poor. We assessed the feasibility of a randomised controlled trial complex intervention, which combines display real time data and behaviour change techniques.
Adherence to nebulizer treatments in adults with cystic fibrosis (CF) is often low. A new complex intervention help CF increase their adherence was tested a pilot randomized controlled trial (RCT) 2 UK centers. Patients used electronic monitoring capabilities that transferred data automatically digital platform (CFHealthHub) monitor over time and tailored website display graphs of educational problem-solving information about adherence. trained interventionist helped patients identify ways...
Forgetting is often cited as a reason why people struggle to adhere treatments for chronic conditions. Interventions have tried improve forgetting behavior using reminders. We used discursive psychological approach explore differences in how high and low adherers constructed their nebulizer cystic fibrosis. Interviews were conducted with 18 adults from fibrosis center the United Kingdom. High occasional lapses automaticity temporary memory that they found easy repair. Low utilized normalize...
To undertake a process evaluation of an adherence support intervention for people with cystic fibrosis (PWCF), to assess its feasibility and acceptability.Two UK (CF) units.Fourteen adult PWCF; three professionals delivering ('interventionists'); five multi-disciplinary CF team members.Nebuliser data recording transfer capability, linked software platform, strategies nebulised treatments facilitated by interventionists over 5 months (± 1 month).Feasibility acceptability the intervention,...
A multi-component self-management intervention 'CFHealthHub' was developed to reduce pulmonary exacerbations in adults with Cystic Fibrosis (CF) by supporting adherence nebuliser medication. It evaluated a randomized controlled trial (RCT) involving 19 CF centres, 32 interventionists, 305 participants the group, and 303 standard care arm. Ensuring treatment fidelity of delivery crucial ensure that produced expected outcomes.
Background People with cystic fibrosis frequently have low levels of adherence to inhaled medications. Objectives The objectives were develop and evaluate an intervention for adults improve their medication. Design We used agile software methods online platform. mixed a behaviour change delivery by interventionist. These integrated become the CFHealthHub intervention. undertook feasibility study consisting pilot randomised controlled trial process evaluation in two centres. evaluated using...
Background Self-efficacy is an important determinant of treatment adherence, and peer modelling success can provide vicarious self-efficacy. A series patient stories ('talking heads' videos) were developed with people cystic fibrosis (CF) as part the CFHealthHub multi-component adherence intervention, aiming to demonstrate daily therapy in 'people like me'. Methodology One-to-one semi-structured interviews exploring patients' experiences, barriers facilitators nebuliser audio video-recorded...
Where universities focus on the benefits of technology-enhanced learning (TEL), they tend to underestimate impact learners’ experiences and wellbeing. The goal research reported in this article was investigate how new technologies ubiquitous connectivity affect students’ day-to-day life, habits consequent psychosocial A mixed methods approach taken allow qualitative data (stage 1) inform development a quantitative measure 2). Stage 1 involved 88 students eight staff participating...
Cystic Fibrosis (CF) is a genetic disease that affects around 10,000 individuals in the UK. Individuals with CF are prone to lung infections; inhaled medications required stay healthy, costing £30 million annually, yet average adherence has been estimated at 36%. Patients 80% of prescribed medication). This both costly healthcare system and distressing for patients their families. protocol details procedures two-armed, superiority, open-labelled randomised controlled trial parallel, mixed...
<h3>Background</h3> Adherence to preventative nebulised therapy is associated with better health and lower costs for rescue treatment. However, adherence treatment generally poor there currently no systematic intervention people CF. The Sheffield Adult CF centre has embarked on various pilot projects in this area, culminating an NIHR programme grant awarded 2014 develop such a intervention. We hypothesised that the would have improved levels outcomes among receiving care at centre....