A5020685000- Ionic liquids properties and applications
- Metal complexes synthesis and properties
- Nanocluster Synthesis and Applications
- Nanomaterials for catalytic reactions
- Catalytic Processes in Materials Science
- Polyoxometalates: Synthesis and Applications
- Nanoparticle-Based Drug Delivery
- Signaling Pathways in Disease
- Advanced Polymer Synthesis and Characterization
- Catalysis and Hydrodesulfurization Studies
- Lanthanide and Transition Metal Complexes
- Catalysis and Oxidation Reactions
- Asymmetric Hydrogenation and Catalysis
- HIV/AIDS drug development and treatment
- Oxidative Organic Chemistry Reactions
- CAR-T cell therapy research
- Carbon dioxide utilization in catalysis
- Innovative Microfluidic and Catalytic Techniques Innovation
- Metal-Organic Frameworks: Synthesis and Applications
- Supramolecular Chemistry and Complexes
- Chemical Synthesis and Reactions
- Supercapacitor Materials and Fabrication
- Block Copolymer Self-Assembly
- Drug Transport and Resistance Mechanisms
- Quinazolinone synthesis and applications
Hebrew University of Jerusalem
2010-2017
A nanoformulated trinuclear hydrolysis product of a bis(alkoxo) salan–TiIV complex shows high antitumor activity (see picture), which identifies it as an active species in cells. Additional highly stable mononuclear derivatives also show activity, when formulated into nanoparticles, thus evincing that biologically friendly TiIV can provide cytotoxicity with controlled biological function.
A method for the preparation of silica microcapsules containing a high loading ionic liquids (ILs) is described. The paves way to conversion into particulated materials, which results in ILs with new properties without changing their molecular structures. synthesis these materials based on emulsification water, using surfactants or dispersants, and resulting liquid droplets are then confined shell formed via interfacial hydrolysis polycondensation tetraethoxysilane. This material can be...
Abstract Nanoparticles of titanium(IV) complexes phenolato ligands were formed and evaluated for cytotoxicity toward human HT‐29 colon cancer, murine T‐25 lymphoma, HU‐2 multidrug‐resistant (MDR) cells. The nano‐formulation, besides increasing the complexes′ shelf lives, is particularly efficient in overcoming limitations solubility cell‐penetration, thus enhancing biological accessibility; large that inactive when measured a non‐formulated form showed marked activity nano‐formulated. For...
We report the preparation of magnetically separable catalytic polymeric nanoreactors by simultaneous encapsulation palladium and magnetite nanoparticles within polyurea nanocapsules. The new material is applied in aqueous hydrogenation reactions.
A family of block copolymers featuring dynamically controlled compositions is presented. These copolymers, termed "quasi-block copolymers" (q-BCP), consist a supramolecular polymer as one the blocks. conventional end-capped with functionality that complementary to monomer used terminate block, giving rise copolymer architecture. In this work we have utilized N,N′-2,4-bis((2-ethylhexyl)ureido)toluene (EHUT) and employed two types modified 2,4-bis(ureido)toluene polystyrenes end-functionalized...
Das nanoformulierte dreikernige Hydrolyseprodukt eines Bis(alkoxo)-Salan-TiIV-Komplexes zeigt hohe Antitumoraktivität (siehe Bild). Weitere hochstabile einkernige Derivate zeigen ebenfalls Aktivität nach ihrer Formulierung in Nanopartikeln und bestätigen damit, dass TiIV Zytotoxizität mit kontrollierter biologischer Funktion bereitstellen kann.
Antitumoraktive Metallowirkstoffe basierend auf biologisch freundlichem Titan(IV) bieten attraktive Alternativen zur derzeit genutzten Platin-basierten Chemotherapie. In der Zuschrift S. 10667 ff. berichten E. Y. Tshuva, Magdassi et al. über die hohe Antikrebs-Aktivität wasserresistenter, in Nanopartikel formulierter Salan-Titan(IV)-Verbindungen. Eine zelluläre aktive Spezies wurde ebenfalls identifiziert.