Milan Obradović

ORCID: 0000-0002-4769-2652
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About
Contact & Profiles
Research Areas
  • Ion Transport and Channel Regulation
  • Liver Disease Diagnosis and Treatment
  • Thyroid Disorders and Treatments
  • Adipokines, Inflammation, and Metabolic Diseases
  • Nitric Oxide and Endothelin Effects
  • Hormonal Regulation and Hypertension
  • Adipose Tissue and Metabolism
  • Metabolism, Diabetes, and Cancer
  • Pain Management and Treatment
  • Thyroid Cancer Diagnosis and Treatment
  • Cerebrovascular and Carotid Artery Diseases
  • Growth Hormone and Insulin-like Growth Factors
  • Regulation of Appetite and Obesity
  • Pancreatic function and diabetes
  • Estrogen and related hormone effects
  • Blood Coagulation and Thrombosis Mechanisms
  • Ion channel regulation and function
  • Musculoskeletal pain and rehabilitation
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Eicosanoids and Hypertension Pharmacology
  • Transcranial Magnetic Stimulation Studies
  • Lipoproteins and Cardiovascular Health
  • Iron Metabolism and Disorders
  • Protease and Inhibitor Mechanisms
  • Cardiovascular Disease and Adiposity

University of Belgrade
2016-2025

Roche (Switzerland)
2024

University of Novi Sad
2023

Saluda Medical (Australia)
2019-2023

Vinča Institute of Nuclear Sciences
2020

Data61
2011-2015

Institut za kardiovaskularne bolesti Dedinje
2015

Albany College of Pharmacy and Health Sciences
2015

Institute for Pulmonary Diseases of Vojvodina
2015

Istituto Euro Mediterraneo di Scienza e Tecnologia
2013

Summary Aβ sensory nerve fibres are recruited during therapeutic spinal cord stimulation and the potential amplitude correlates with degree of coverage painful area. Electrical provides effective pain relief to hundreds thousands chronic neuropathic sufferers. The therapy involves implantation an electrode array into epidural space subject then dorsal column electrical pulses. depolarises axons generates propagating action potentials that interfere perception pain. Despite long-term clinical...

10.1016/j.pain.2011.11.023 article EN Pain 2011-12-19

<h3>Importance</h3> Chronic pain is debilitating and profoundly affects health-related quality of life. Spinal cord stimulation (SCS) a well-established therapy for chronic pain; however, SCS has been limited by the inability to directly measure elicited neural response, precluding confirmation activation continuous therapy. A novel system measures evoked compound action potentials (ECAPs) produce real-time physiological closed-loop control system. <h3>Objective</h3> To determine whether...

10.1001/jamaneurol.2021.4998 article EN JAMA Neurology 2022-01-08

Introduction The evidence for spinal cord stimulation (SCS) has been criticized the absence of blinded, parallel randomized controlled trials (RCTs) and limited evaluations long-term effects SCS in RCTs. aim this study was to determine whether evoked compound action potential (ECAP)-controlled, closed-loop (CL-SCS) is associated with better outcomes when compared fixed-output, open-loop (OL-SCS) 36 months following implant. Methods EVOKE a multicenter, participant-blinded,...

10.1136/rapm-2023-104751 article EN cc-by-nc Regional Anesthesia & Pain Medicine 2023-08-27

Non-alcoholic fatty liver disease (NAFLD), metabolic syndrome (MetS), and type 2 diabetes (T2DM) are disorders that belong to highly prevalent cluster with a significant impact on public health worldwide. MetS is complex condition characterized by metabolism perturbations include glucose intolerance, insulin resistance, dyslipidemia, associated pro-inflammatory state arterial hypertension. As the components of commonly co-occur, management these could not be considered separate issues. Thus...

10.5114/aoms/150639 article EN cc-by-nc-sa Archives of Medical Science 2022-06-03

Obesity alters lipid and carbohydrate metabolism, which has an impact on micronutrient status. Zinc affects glucose metabolism while also acting as anti-inflammatory antioxidant in various physiological processes. It a direct effect the insulin-signaling system acts insulin mimic. In this study we predicted that zinc deficiency obese Serbian adults anthropometric parameters, metabolic profiles, inflammation, atherosclerotic markers. We conducted case-control with 31 adult individuals...

10.1080/00365513.2025.2460034 article EN Scandinavian Journal of Clinical and Laboratory Investigation 2025-02-03

The endothelium consists of a monolayer Endothelial Cells (ECs) which form the inner cellular lining veins, arteries, capillaries and lymphatic vessels. ECs interact with blood lymph. fulfils functions such as vasodilatation, regulation adhesion, infiltration leukocytes, inhibition platelet vessel remodeling lipoprotein metabolism. synthesize release compounds Nitric Oxide (NO), metabolites arachidonic acid, Reactive Oxygen Species (ROS) enzymes that degrade extracellular matrix. dysfunction...

10.2174/0929867326666190903112146 article EN Current Medicinal Chemistry 2019-09-04
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