A5030781745- Flame retardant materials and properties
- Polymer Nanocomposites and Properties
- biodegradable polymer synthesis and properties
- Synthesis and properties of polymers
- Crystallization and Solubility Studies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Natural Fiber Reinforced Composites
- Electrospun Nanofibers in Biomedical Applications
- Fire dynamics and safety research
- Spectroscopy and Chemometric Analyses
- Drug Solubulity and Delivery Systems
- Fiber-reinforced polymer composites
- Protein purification and stability
- Silicone and Siloxane Chemistry
- Polymer Foaming and Composites
- Injection Molding Process and Properties
- Epoxy Resin Curing Processes
- Process Optimization and Integration
- Spectroscopy Techniques in Biomedical and Chemical Research
- Polymer composites and self-healing
- Pesticide Exposure and Toxicity
- Viral Infectious Diseases and Gene Expression in Insects
- Thermal and Kinetic Analysis
- Organophosphorus compounds synthesis
- Advanced Sensor and Energy Harvesting Materials
Budapest University of Technology and Economics
2015-2024
Budapest Institute
1999-2004
Eötvös Loránd University
1999-2004
University of Szeged
1980-2001
Innovation in the pharmaceutical industry has been limited for a long time to research and development of new active compounds; meanwhile, structure production, dominated by batchwise technologies, not changed date. As already demonstrated several other industrial sectors, continuous manufacturing (CM) many advantages over batch processes. Faster, cheaper, more flexible production can be developed with significantly higher level quality assurance. In recent years main regulatory agencies...
An end-to-end continuous pharmaceutical manufacturing process was developed for the production of conventional direct compressed tablets on a proof-of-concept level first time. The output reaction mixture flow synthesis acetylsalicylic acid crystallized continuously in mixed suspension product removal crystallizer. crystallizer directly connected to filtration carousel device, thus crystallization, and drying (ASA) carried out an integrated 2-step process. Steady state reached during longer...
An innovative, Raman spectroscopy-based monitoring and control system is introduced in this paper for designing dynamic feeding strategies that allow the maintenance of key cellular nutrients at an ideal level Chinese hamster ovary cell culture. The Partial Least Squares calibration models built glucose, lactate 16 (out 20) individual amino acids had very good predictive power with low root mean square errors values high correlation coefficients. developed used real-time measurement nutrient...
Abstract Fire retardancy behavior of polypropylene–magnesium hydroxide–clay composites different morphologies is presented. Layer‐ and needle‐like clay nanoparticles in natural organically surface modified form have been compared. retardant performance the was evaluated by conical combustor horizontal burning test, while structure characterized SEM. Rheological analysis varied temperature provided further information about strength formed combustion residue. The results confirm that fibrous...
The pharmaceutical industry has never seen such a vast development in process analytical methods as the last decade. application of near-infrared (NIR) and Raman spectroscopy monitoring production lines also become widespread. This work aims to utilize large amount information collected by these building an artificial neural network (ANN) model that can predict dissolution profile scanned tablets. An extended release formulation containing drotaverine (DR) drug was developed tablets were...
The Process Analytical Technology (PAT) and the Quality-by-Design (QbD) approaches can efficiently facilitate shift to desired continuous manufacturing real time release testing (RTRT). By this, it is vital develop new, in-line analytical methods which fulfil pharmaceutical requirements. fast-developing digital imaging-based machine vision systems provide revolutionary solutions not just in automotive industry but technology, as well. This study aimed explore capabilities of UV/VIS-based...
Ammonium-polyphosphate (APP) was modified by microencapsulation with a bio-based sorbitol polyglycidyl ether (SPE)-type epoxy resin and used as flame retardant additive in polylactic acid (PLA) matrix. The bioresin-encapsulated APP (MCAPP) particles were characterized using Fourier transform infrared (FTIR) spectroscopy Raman mapping, particle size distribution determined processing of scanning electron microscopic (SEM) images. Interaction between the core bioresin shell revealed combined...
2-hydroxypropyl-β-cyclodextrin (HP-β-CD) microfibres with diameters ranging between 3 and 7 µm were prepared by aqueous solution based high-speed electrospinning (HSES) technique then used as carbonising agent at wt% loading besides 15 ammonium polyphosphate (APP) to obtain flame-retarded poly(lactic acid) (PLA) composites. The high specific surface area of the microfibrous HP-β-CD was found have a crucial role in its flame retardant efficiency. Compared effect same amount conventional...
Abstract A fully biobased waterborne flame‐retarded epoxy system was prepared using sorbitol polyglycidyl ether resin (SPE) and phytic acid (PA) as a reactive flame retardant (FR). The flame‐retardant efficiency evaluated by comparing the reference SPE‐PA with solventborne SPE systems. Additional enhancement of intumescence reduction flammability achieved incorporating ammonium polyphosphate (APP) melamine (MEL) into SPE–PA system. PA, serving curing agent, contributed approximately 1%...
Abstract Addition of Ammonium Polyphosphate/Polyamide‐6 system is known to provide flame retardancy in many polymers blends via an intumescent process. Particulate fillers (talc and calcium carbonate) are used large quantities PP. Combination PP can modify the properties polymeric matrix. This study investigates effect on fire performance Polypropylene/Ammonium polyphosphate/Polyamide‐6 blend. It shown that strongly depends nature filler used. Talc increases carbonate decreases
The aim of this work was to investigate the effect phosphorus-based additive and reactive flame retardants (FR) on flammability mechanical properties a pentaerythritol-based model epoxy resin system cured with cycloaliphatic diamine hardener. Commercially available ammonium polyphosphate (APP) used as 9,10-dihydro-9-oxa-10-phosphaphenantrene-10-oxide (DOPO) retardant. behaviour these systems also compared recently synthesized phosphorus-containing amine (TEDAP), which can be both retardant...