A5077588001- Phase Equilibria and Thermodynamics
- Chemical Thermodynamics and Molecular Structure
- Analytical Chemistry and Chromatography
- Process Optimization and Integration
- Computational Drug Discovery Methods
- Chemical and Physical Properties in Aqueous Solutions
- Thermodynamic properties of mixtures
- Crystallization and Solubility Studies
- Ionic liquids properties and applications
- Adsorption, diffusion, and thermodynamic properties of materials
- Coffee research and impacts
- Essential Oils and Antimicrobial Activity
- Machine Learning in Materials Science
- Thermal and Kinetic Analysis
- Catalysis for Biomass Conversion
- Phytochemistry and Biological Activities
- Subcritical and Supercritical Water Processes
- Fermentation and Sensory Analysis
- Microbial Metabolic Engineering and Bioproduction
- Polysaccharides Composition and Applications
- Algal biology and biofuel production
- Plant-derived Lignans Synthesis and Bioactivity
- Membrane-based Ion Separation Techniques
- Advanced Thermodynamics and Statistical Mechanics
- Zeolite Catalysis and Synthesis
Institute of Chemical Engineering
2014-2024
Bulgarian Academy of Sciences
2014-2024
University of Chemical Technology and Metallurgy
2002-2009
Universidad Autónoma de Madrid
2005-2009
Universitat de València
2005-2009
Ben-Gurion University of the Negev
2002-2009
Tel Aviv University
2006-2009
Imperial College London
1995-2008
University of Szeged
2007
University of Southampton
2002-2004
In the 21st century, mission of chemical engineering is to promote innovative technologies that reduce or eliminate use generation hazardous materials in design and manufacture products. The sustainable renewable resources, complying with consumer health environmental requirements, motivates design, optimisation, application green benign processes. Supercritical fluid extraction a typical example novel technology for ecologically compatible production natural substances high industrial...
Thymol (2-isopropyl-5-methylphenol) is the main monoterpene phenol found in thyme essential oil. This compound has revealed several biological properties, including antibacterial, anti-inflammatory and antioxidant activities. In this work, a comparison was made between performance of different green solvents (ethanol, limonene ethyl lactate), by pressurized liquid extraction (PLE) supercritical fluid (SFE) at conditions, to extract thymol from three varieties (Thymus vulgaris, Thymus zygis...
The use of biomass, particularly, a second-generation one, as renewable raw material is crucial to sustain the chemical industry. To favor development such processes, one needs make cost evaluation, which requires knowledge process thermodynamics and kinetics. In this paper, measurements different physicochemical properties (viscosity, density, refractive index, specific heat capacity) were done for systems: hydrogenation levulinic acid or its esters γ-valerolactone. From those measurements,...
The paper provides new correlations for the estimation of relative liquid density and critical parameters hydrocarbons. employ molecular descriptors from computer simulation mechanics, which proved valuable in our previous work. High precision is achieved, without use unduly complex rules, as a result improved methodology. methodology includes limit upon functionality property database its predesign by expanding range improving distribution repeating structural features selected compounds.A...
Solubility data of solid 3,4,5-trihydroxybenzoic acid (gallic acid) in supercritical CO2 + ethanol as a cosolvent are reported this work. Measurements were carried out the temperature range (313.15 to 333.15) K, pressures ranging from (10 40) MPa, and different modifier content (0.7 6) %. The experimental correlated using Soave−Redlich−Kwong equation state group contribution associating state. thermodynamic modeling analysis includes also solubility representation an important class natural...
In this study, sustainable technology microwave-assisted extraction (MAE) in association with green solvents was applied to recover phenolic compounds from spent coffee grounds (SCGs). A design of experiments (DOE) used for process optimization. Initially, a 24-1 two level Fractional Factorial Design and ratios "solvent solute" "ethanol water" were identified as the significant experimental factors. Consequently, Central Composite (CCD) analyze effects variables on response yield, total...
From the time levulinic acid was listed as one of top-12 building blocks for sugars-high value compounds conversion, interest in this compound increased. As part its possible production route, definition viable separation schemes appears paramount importance overall development exploitation. Hybrid sequences where liquid-liquid extraction is followed by distillation were considered proving how direct and -indirect appeared to be best alternatives terms total annual cost environmental impact....
Experimental and modeling studies of the liquid−liquid equilibria at ambient pressure three model systems—squalene + ethyl lactate, olive oil squalene lactate—were performed with view to explore potential application an agrochemical solvent, namely, recover from pretreated deodorizer distillate. The favorable separation factors obtained reveal strength lactate as a green solvent for recovery triglyceride mixtures.
Solubility measurements of quinizarin (1,4-dihydroxyanthraquinone), disperse red 9 (1-(methylamino) anthraquinone), and blue 14 (1,4-bis(methylamino)anthraquinone) in supercritical carbon dioxide (SC CO2) were carried out a flow type apparatus, at temperature range from (333.2 to 393.2) K pressures (12.0 40.0) MPa. Mole fraction solubility the three dyes decreases order (2.9 × 10−6 2.9.10−4), (1.4 3.2 10−4), (7.8 10−8 2.2 10−5). Four semiempirical density-based models used correlate SC CO2....
In this work, a novel sustainable approach was proposed for the integral valorisation of Arctium lappa (burdock) seeds and roots. Firstly, preliminary recovery bioactive compounds, including unsaturated fatty acids, performed. Then, simple sugars (i.e., fructose sucrose) phenolic compounds were extracted by using compressed fluids (supercritical CO2 propane). Consequently, complete characterisation raw biomass extraction residues carried out to determine starting chemical composition in...
Prediction of unknown properties for a target compound using quantitative structure−property relationships (QSPRs) is reliable only if the within model applicability domain. To improve prediction reliability, "targeted" QSPR (TQSPR) method developed in which training set containing compounds structurally similar to first identified. Similarity measured by partial correlation coefficients between vectors molecular descriptors and each potential predictive compound. Available property data are...
This work investigates the prospects for exploitation of Gnaphalium viscosum (Kunth) abundant but with limited applications till present biomass. The feasibility traditional techniques (two-phase solvent, and benchmark Soxhlet extraction) supercritical extraction without/with a cosolvent at T = 40-60 °C p 30-50 MPa was examined to explore possibility recovering phytochemicals from G. leaves, flowers stems. efficiency assessed compared based on yield, influence solvents used, total phenolic...