A5039053657- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Chemical Synthesis and Analysis
- Chemical Reaction Mechanisms
- Crystallography and molecular interactions
- Ionic liquids properties and applications
- Molecular spectroscopy and chirality
- Dendrimers and Hyperbranched Polymers
- Protein Interaction Studies and Fluorescence Analysis
- Coordination Chemistry and Organometallics
- Petroleum Processing and Analysis
- Advanced NMR Techniques and Applications
- RNA Interference and Gene Delivery
- Heat transfer and supercritical fluids
- Spectroscopy and Quantum Chemical Studies
- Algal biology and biofuel production
- Advanced Battery Materials and Technologies
- Hemoglobin structure and function
- Surfactants and Colloidal Systems
- Solid-state spectroscopy and crystallography
- Seaweed-derived Bioactive Compounds
- Protein Structure and Dynamics
- Synthesis and Properties of Aromatic Compounds
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Asymmetric Synthesis and Catalysis
St Petersburg University
2015-2024
Resonance Research (United States)
2019
The dibenziodolium cation displays high catalytic activity for the Knorr-type reactions <italic>via</italic> binding with carbonyl O atom.
A brief overview is given of the papers published over last two decades on subject solid-state 13C NMR spectra such carbon nanostructures as milled graphite and its oxide, graphene, graphene nanotubes, nanodiamonds, fullerenes their derivatives. The main focus put characteristic values experimental isotropic chemical shifts interpretation in terms local environments nuclei.
The esterase status of blood plasma can claim to be one the universal markers various diseases; therefore, it deserves attention when searching for severity COVID-19 and other infectious non-infectious pathologies. When analyzing plasma, activity serum albumin, which is major protein in mammals, should not ignored. purpose this study expand understanding evaluate relationship status, includes information on amount enzymatic human albumin (HSA), with biochemical parameters blood, using...
A new poly-<sc>l</sc>-lysine dendrimer with arginine residues was synthesized and its structure physical–chemical properties were analyzed by NMR spectroscopy.
Peptide dendrimers are good candidates for diverse biomedical applications due to their biocompatibility and low toxicity. The local orientational mobility of groups with different radial localization inside is important characteristic drug gene delivery, synthesis nanoparticles, other specific purposes. In this paper we focus on the validation two theoretical assumptions dendrimers: (i) independence NMR relaxations excluded volume effects (ii) similarity mobilities side terminal segments...
In this paper we study two lysine-based peptide dendrimers with Lys-His-Arg and Lys-Arg-His repeating units terminal lysine groups. Combination of His Arg properties in a dendrimer could be important for biomedical applications, especially prevention aggregation penetration through various cell membranes. We describe the synthesis these confirmation their structure using 1D 2D Nuclear Magnetic Resonance (NMR) spectroscopy. NMR spectroscopy relaxation are used to structural dynamic...
Peptide dendrimers, due to their biocompatibility and low toxicity, are highly promising candidates as nanocarriers for drugs genes. The development of this kind delivery system requires reliable monitoring metabolic biological pathways. In respect, hydrogen isotope labeling has tremendous importance, being a safe tool detection the labeled nanocarriers. work, we have synthesized new histidine-rich lysine-based dendrimers (Lys-2His dendrimer) with two linear histidine (His) residues in every...
Serum albumin possesses esterase and pseudo-esterase activities towards a number of endogenous exogenous substrates, but the mechanism interaction various esters other compounds with is still unclear. In present study, proton nuclear magnetic resonance (1H NMR) has been applied to study true activity albumin, using example bovine serum (BSA) p-nitrophenyl acetate (NPA). The site BSA was then determined molecular modelling methods. According data obtained, accumulation in presence reaction...
It has been found that 1,8-bis(dimethylamino)naphthalene (DMAN), unlike N,N-dimethylaniline, undergoes ring metallation in the n-BuLi-TMEDA-Et2O system with a low selectivity and poor total yields. The situation is significantly improved t-BuLi-TMEDA-n-hexane when 3- 4-lithium derivatives become only reaction products obtained good formation of 3-Li-DMAN especially desired since no method direct meta-functionalization DMAN known to date. relative stability structure lithium have examined...
The protonation of the carboxamide nitrogen atom is an essential part in vivo and vitro processes (cis-trans isomerization, amides hydrolysis etc). This phenomenon well studied geometrically strongly distorted amides, although there little data concerning undistorted amides. In latter case, participation amide hydrogen bonding (which can be regarded as incipient state a proton transfer process) less well-studied. Thus, it would worthy goal to investigate enthalpy this interaction. We...
Data are accumulating on the hydrolytic activity of serum albumin towards esters and organophosphates. Previously, with help technology proton nuclear magnetic resonance (
The aggregation of a series mono- and dilithionaphthalenes in THF solutions the presence tetramethylethylenediamine (TMEDA) pentamethyldiethylenetriamine (PMDTA) was studied by NMR spectroscopy quantum chemical calculations. stability dimeric species diluted as well reasons their disaggregation some cases has been discussed. For lithioderivatives 1,8-bis(dimethylamino)naphthalene (DMAN) possibility NMe2 group coordination to lithium atom ortho-position naphthalene core under steric pressure...
Tetrabromomethane functions as an organic catalyst for non‐redox reactions of carbonyl species and, in particular, it enhances the aldehyde–acyl hydrazide condensation to give N ‐acyl hydrazones. This simple, inexpensive, and commercially available halomethane provides up 14‐fold acceleration Schiff reaction; kinetic data indicate that studied exhibits first order on CBr 4 . The catalytic activity is significantly higher than other halogen‐containing species, such CHX 3 or ArX (X = Cl, Br, I).
Dendrimers are regular hyperbranched macromolecules. The complex structure of the relaxation spectrum is one many features dendrimers that does not fit into classical concepts polymers. manifested in various dynamic processes, including NMR relaxation. In this work, we study collapsed and swollen using experiments atomistic simulations modified lysine-based dendrimer with double histidine insertions (Lys-2His). This considered most suitable because imidazole groups charged at a normal pH...
Zinc(II)-catalyzed (10 mol % ZnCl2) coupling of acyl hydrazides and dialkylcyanamides in ethanol leads to 3-dialkylamino-1,2,4-triazoles (76-99%; 17 examples). This reaction represents a novel, straightforward, high-yielding approach practically important 3-NR2-1,2,4-triazoles, which utilizes commercially available and/or easily generated substrates. Seventeen new 3-NR2-1,2,4-triazoles were characterized by HRESI+-MS IR, 1H, 13C{1H} NMR spectroscopies five species additionally single-crystal...
The main purpose of this study is to investigate the local structure and dynamics in ‘water-in-salt’ solutions, namely ternary concentrated LiCl–CsCl–D<sub>2</sub>O electrolytes.