A5103094491- Reproductive Biology and Fertility
- Heme Oxygenase-1 and Carbon Monoxide
- Cardiovascular Function and Risk Factors
- Sirtuins and Resveratrol in Medicine
- Adipose Tissue and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Viral Infections and Vectors
- Hematological disorders and diagnostics
- Viral Infections and Immunology Research
- Esophageal and GI Pathology
- Electrospun Nanofibers in Biomedical Applications
- Hepatitis C virus research
- Myofascial pain diagnosis and treatment
- Vitamin D Research Studies
- Molecular Communication and Nanonetworks
- PARP inhibition in cancer therapy
- Engineering Applied Research
- Micro and Nano Robotics
- Phytochemistry and biological activity of medicinal plants
- Nitric Oxide and Endothelin Effects
- Birth, Development, and Health
- Ear and Head Tumors
- Microfluidic and Bio-sensing Technologies
- Urinary Tract Infections Management
- GDF15 and Related Biomarkers
Huazhong University of Science and Technology
2016-2025
First Affiliated Hospital of Zhengzhou University
2021-2025
Union Hospital
2024-2025
China Electric Power Research Institute
2025
Guang’anmen Hospital
2017-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2017-2023
China Academy of Chinese Medical Sciences
2021
Cooper University Hospital
2021
Eye & ENT Hospital of Fudan University
2021
First Affiliated Hospital of Wenzhou Medical University
2011-2019
ABSTRACT Recent studies have shown that disruptions in the nicotinamide adenine dinucleotide (NAD + ) de novo synthesis pathway accelerate ovarian aging, yet its role spermatogenesis remains largely unknown. In this study, we investigated impact of NAD on by generating Qprt ‐deficient mice using CRISPR‐Cas9 to target quinolinate phosphoribosyl transferase ( ), a key enzyme predominantly expressed spermatocytes. Our results revealed deletion did not affect levels or testes 3‐month‐old mice....
Artificial micromotors have a demonstrated value in the biomedical area. Attempts to develop this technology tend impart with novel functions improve values. Herein, we present structural color-barcode for multiplex assays. We found that, by rapidly extracting solvent and assembling monodispersed nanoparticles droplets, it could form stomatocyte colloidal crystal clusters, which not only showed striking colors characteristic reflection peaks due their ordered arrangement, but also provided...
Double-stranded RNA-dependent protein kinase (PKR) is a eukaryotic initiation factor 2α that inhibits mRNA translation under stress conditions. PKR also mediates inflammatory and apoptotic signaling independently of translational regulation. Congestive heart failure associated with cardiomyocyte hypertrophy, inflammation, apoptosis, but the role in left ventricular hypertrophy development congestive has not been examined.We observed increased myocardial expression translocation into nucleus...
Recently, neutrophil/lymphocyte ratio (NLR) has been proved to be a useful indicator of inflammation and cardiovascular risk. Brachial-ankle pulse wave velocity is an for early atherosclerotic changes. It unknown whether NLR differs in subtypes hypertension, little research performed on the relationship between arteriosclerosis hypertension. The purpose this article was investigate their relationship. A total 217 consecutive patients with hypertension 132 persons without were included. All...
In response to several stresses, including nutrient deprivation, general control nonderepressible 2 kinase (GCN2) attenuates mRNA translation by phosphorylating eukaryotic initiation factor 2α Ser51 . Energy starvation is known exacerbate congestive heart failure, and phosphorylation increased in the failing heart. However, effect of GCN2 during evolution failure has not been tested. this study, we examined influence expression a cardiac stress inducing chronic pressure overload with...
Very fast transient overvoltage (VFTO) is characterized by short wavefront time, high amplitude and wide frequency. VFTO poses a threat to the safe operation of power equipment. In order suppress harmful effects transmission on equipment, new type busbar based structure “inductance + resistance” has been designed, which called “damping busbar”. this study, equivalent circuit damping bus including spurious parameters was developed. These stray are formed between GIS enclosure bus, disk...
Heat stress induces testicular oxidative stress, impairs spermatogenesis, and increases the risk of male infertility. Recent studies have highlighted antioxidative properties Sestrins family in reducing cellular damage. However, role (Sestrin1, 2, 3) response to heat remains unclear. Here, we found that Sestrin2 3 were highly expressed testis relative Sestrin1. Then, Sestrin2-/- Sestrin3-/- mice generated by CRISPR/Cas9 investigate them on spermatogenesis after stress. Our data showed testes...
Heart failure (HF) is one of the common and critical disease, often accompanied by increased level serum bilirubin, but role an indicator bilirubin to monitor prognosis patients with heart still unclear, so we implemented study systematically evaluate predictive value in HF.A comprehensive search systematic review will be conducted on electronic databases such as Medline, Cochrane Library, Embase, Web Science, Clinical Trials Database relationship between HF patients. Review Manager software...
Objective: To compare the therapeutic efficacy of tenofovir disoproxil fumarate (TDF) and entecavir (ETV) in patients with chronic Hepatitis-B (CHB). Methods: This retrospective study included 110 CHB who received treatment at The First People’s Hospital Linping District, Hangzhou from January 2021 to 2023. Clinical data were reviewed classified according received: TDF group (n=53, treatment) ETV (n=57, treatment). virus deoxyribonucleic acid (HBV DNA) levels, liver function indicators,...
Background Invasive pulmonary aspergillosis (IPA) typically occurs in immunocompromised individuals. Severe fever with thrombocytopenia syndrome (SFTS) patients are characterized by fever, thrombocytopenia, and leukopenia. These present dysregulation of cellular humoral immunity, which may predispose them to IPA. Our study aimed identify risk factors for SFTS-associated invasive (SAPA) evaluate its associated prognostic impact. Methods We conducted a cohort between January 2017 December 2022...
Autophagy is essential for the maintenance of cellular homeostasis and activated in mouse liver cells by amino acid deprivation. A low protein diet during gestation lactation has been associated with poor fetal development but consequence mother not fully investigated. This study aims to investigate effects a on physiology dams characterize hepatic autophagy. Timed‐pregnant Sprague‐Dawley rats were fed control (control, 20 kcal% protein) or (LP, 8 lactation. Dam was collected analysis at...
Objective To study the imaging characteristics of vesical leukoplakia under cys-toscope system. Methods The were observed cystoscope system in 556 cases. After anti-infection treatment to these patients, chan-ges characteristic cystoseope re-observed and compared before after treatment. SPSS 11.0 software package x2 teat for statistical analysis was used. Results Under system, there four different manifestations pa-tients. These were, from mild severe, congestive type 42 cases, spots 56 thin...