- Vestibular and auditory disorders
- Neuroscience of respiration and sleep
- Neuroscience and Neuropharmacology Research
- Ophthalmology and Eye Disorders
- Mitochondrial Function and Pathology
- Hearing, Cochlea, Tinnitus, Genetics
- Glaucoma and retinal disorders
- Advanced Neuroimaging Techniques and Applications
- Neurogenesis and neuroplasticity mechanisms
- Retinal Development and Disorders
- Cellular transport and secretion
- Cerebrospinal fluid and hydrocephalus
- Neurology and Historical Studies
- Olfactory and Sensory Function Studies
- Neural dynamics and brain function
- Sleep and Wakefulness Research
- Diet and metabolism studies
- Neuroscience, Education and Cognitive Function
- Comparative Animal Anatomy Studies
- Photoreceptor and optogenetics research
- Epilepsy research and treatment
- Memory and Neural Mechanisms
- History of Medicine Studies
- Neurobiology and Insect Physiology Research
- Neurological diseases and metabolism
Erasmus University Rotterdam
2004-2021
Erasmus MC
2009-2021
University of Bristol
2003
Rotterdam University of Applied Sciences
1989-1994
Leiden University
1977-1987
Aristotle University of Thessaloniki
1983
University of Vermont
1977
After lesions of inferior olive, survival times 5 to 12 days and Nauta staining, degeneration is present in white matter central cerebellar nuclei Deiters' nucleus. Shorter from 40 60 hours Fink-Heimer impregnantion reveal degenerating climbing fiber terminals the molecular layer. With 3H-leucine autoradiography three seven entire trajectory fibers can be traced. Olivocerebellar cross brain stem terminate contralaterally cortex nuclei. Occasional labeling mossy explained by involvement...
Abstract Olivocerebellar fibers from different subnuclei of the rostral inferior olive decussate in brain stem and terminate as climbing one or two narrow, longitudinally arranged zones cerebellar cortex. These issue collaterals to central nucleus that receives its afferents same cortical zone which parent terminate. The medial accessory projects C2 sends posterior interposed nucleus. A differentiation can be made between pole this subnucleus primarily paraflocculus ansiform lobule. More...
Abstract The rostral medial accessory olive (MAO) of the cat was studied by using an ultrastructural technique combining wheat germ agglutinin–coupled horseradish peroxidase (WGA‐HRP) anterograde tracing and postembedding GABA immunocytochemistry. One group cats received a WGA‐HRP injection in posterior interposed nucleus cerebellum another Darkschewitsch. Based on differences their morphology three types GABAergic nonGABAergic terminals were observed. type terminal often GABA/WGA‐HRP...
The cerebellum plays an important role in the visual guidance of movement. In order to understand anatomical basis visuomotor control, we studied projection pontine cells onto cerebellar cortex monkeys. Wheat germ agglutinin horseradish peroxidase was injected into dorsolateral pons two Retrogradely labelled were mapped cerebral and superior colliculus, orthogradely fibers cortex. largest number retrogradely a group medial extrastriate areas. major target these is dorsal paraflocculus. There...
Individual cerebellar cortical zones defined by the somatotopy of climbing fiber responses and their olivo-cortico-nuclear connections located in paramedian lobule copula pyramidis rat cerebellum were microinjected with cholera toxin B subunit. Collateral branches mossy fibers mapped related to pattern zebrin-positive -negative bands Purkinje cells. Climbing collaterals from distribute anterior lobe: mainly lobulus simplex rostral crus I. terminating particular (X, A2, C1, CX, C2, C3, D1,...
The olivocerebellar climbing fiber system was investigated in the rat with anterograde Phaseolus vulgaris leucoagglutinin (PHA-L) tracing. specific objective of study to find morphological evidence collaterals innervating cerebellar nuclei. Small iontophoretic injections PHA-L were placed different parts inferior olivary complex, and labelled fibers could be traced their termination as sagittal zones contralateral cortex. Reaching cerebellum via restiform body, axons entered deep white...
The detailed organization of projections from the inferior olive to cerebellar nuclei rat was studied by using anterograde tracing. presence a collateral projection could be confirmed, and recognized at nuclear subnuclear level. Olivary different parts medial nucleus arise various caudal half accessory olivary nucleus. interstitial cell groups receive afferents intermediate part dorsomedial column. A mediolateral topography noted in rostral posterior interposed lateral are derived principal...
Abstract The localization and termination of olivocerebellar fibers in the flocculus nodulus rabbit were studied with anterograde axonal transport methods [wheatgerm agglutinin‐horseradish peroxidase (WGA‐HRP) tritiated leucine] correlated compartments white matter these lobules delineated acetylcholinesterase histochemistry (Tan et al. J. Comp. Neurol., 1995, this issue). Olivocerebellar originating from caudal dorsal cap travel through floccular FC 2 4 to terminate as climbing zones FZ II...