- Parkinson's Disease Mechanisms and Treatments
- Phytochemical and Pharmacological Studies
- Seaweed-derived Bioactive Compounds
- Sirtuins and Resveratrol in Medicine
- Calcium signaling and nucleotide metabolism
- Biochemical and biochemical processes
- Biochemical Acid Research Studies
- Neuroscience and Neuropharmacology Research
Annamalai University
2010
Parkinson's disease (PD) is the most common neurodegenerative disorder, characterized by loss of dopaminergic neurons in substantia nigra and depletion dopamine striatum due to mitochondrial dysfunction, oxidative stress, excitotoxicity, apoptosis, inflammation proteasome failure.The present study deals with neuroprotective effect resveratrol, a wine polyphenol (50 mg/kg body weight) against MPTP (30mg/kg weight as i.p. administration) induced mice model idiopathic disease.A combination...
In the exploration of bioactive compounds from Turbinaria ornata a brown algae, present study deals with preliminary phytochemicals analysis different solvents along antioxidant and anti-inflammatory activities methanolic extract (TOME) has been investigated for its total activity, in vitro free radical scavenging potential by 2, 2-diphenyl-1-pricrylhydrazyl (DPPH) assay, reducing power Nitric oxide, hydrogen peroxide, superoxide assays. The anti-hemolysis RBC model blood collected healthy...