Ka Yan Tong

ORCID: 0000-0002-4927-3486
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About
Contact & Profiles
Research Areas
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Molecular Sensors and Ion Detection
  • Electrochemical Analysis and Applications
  • Neuroscience and Neuropharmacology Research
  • Metal complexes synthesis and properties
  • Electrochemical sensors and biosensors
  • Crystallography and molecular interactions
  • Intelligent Tutoring Systems and Adaptive Learning
  • Vitamin C and Antioxidants Research
  • Educational Games and Gamification
  • Advanced biosensing and bioanalysis techniques
  • Trace Elements in Health
  • Usability and User Interface Design
  • Alzheimer's disease research and treatments
  • Face and Expression Recognition
  • Nanoparticles: synthesis and applications

University of Hong Kong
2017-2020

State Key Laboratory of Synthetic Chemistry
2019

London School of Economics and Political Science
2015

The development of a new triggered-release system for selective detection catecholamines in biological samples including living cells is reported. Catecholamines are class tightly regulated hormones and neurotransmitters the human body their dysregulation implicated various neurodegenerative diseases. It highly challenging to selectively sense detect complex environment due small size, non-specific molecular shape trivial chemical properties. In this study, copper-based,...

10.1039/c9sc03338f article EN cc-by-nc Chemical Science 2019-01-01

Abstract Ascorbate is an important biological reductant and enzyme cofactor. Although direct detection through ascorbate‐mediated reduction possible, this approach suffers from poor selectivity due to the wide range of cellular reducing agents. To overcome limitation, we leverage potential ascorbate mediate a copper‐mediated oxidative bond cleavage ether‐caged fluorophores. The copper(II) complexes supported by {bis(2‐pyridylmethyl)}benzylamine or {bis(2‐pyridylmethyl)}(2‐methoxybenzyl)amine...

10.1002/chem.202000780 article EN Chemistry - A European Journal 2020-06-25
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