Kuo-Chan Hung

ORCID: 0000-0002-4937-5984
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About
Contact & Profiles
Research Areas
  • Monoclonal and Polyclonal Antibodies Research
  • RNA Interference and Gene Delivery
  • Urinary Tract Infections Management
  • Bacteriophages and microbial interactions
  • Virus-based gene therapy research
  • Electrical Fault Detection and Protection
  • Lipid Membrane Structure and Behavior
  • CAR-T cell therapy research
  • Reproductive tract infections research
  • Fire dynamics and safety research
  • Risk and Safety Analysis
  • Hepatitis B Virus Studies
  • HIV Research and Treatment
  • CRISPR and Genetic Engineering
  • Gout, Hyperuricemia, Uric Acid
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Viral Infectious Diseases and Gene Expression in Insects
  • Immunotherapy and Immune Responses
  • Microfluidic and Capillary Electrophoresis Applications
  • RNA and protein synthesis mechanisms

Harvard University Press
2020

Harvard University
2020

Kao Yuan University
2017

New England Biolabs (United States)
2015

University of Southern California
2007-2013

Southern California University for Professional Studies
2007

Monoclonal antibodies are powerful tools for scientific research and the basis of numerous therapeutics. However, traditional approaches to generate monoclonal against a desired target, such as hybridoma-based techniques display library methods, laborious suffer from fusion inefficiency bias, respectively. Here we present platform, featuring droplet microfluidics bead-based binding assay, rapidly identify verify antigen-binding antibody sequences primary cells. We used defined mixture...

10.1039/d0ra04328a article EN cc-by RSC Advances 2020-01-01

Single-span membrane proteins (ssMPs) represent approximately one-half of all and play important roles in cellular communications. However, like proteins, ssMPs are prone to misfolding aggregation because the hydrophobicity transmembrane helices, making them difficult study using common aqueous solution-based approaches. Detergents mimetics can solubilize but do not always result proper folding functionality. Here, we use cell-free protein synthesis presence oil drops create a one-pot system...

10.1073/pnas.1504992113 article EN Proceedings of the National Academy of Sciences 2015-12-31

Dendritic cell (DC)-based vaccines have shown promise as an immunotherapeutic modality for cancer and infectious diseases in many preclinical studies clinical trials. Provenge (sipuleucel-T), a DC-based vaccine based on ex vivo-generated autologous DCs loaded with antigens, has recently received FDA approval prostate treatment, further validating the potential of modalities. However, direct antigen delivery to vivo via DC-specific surface receptors would enable more less laborious approach...

10.1021/cb300680c article EN ACS Chemical Biology 2013-02-21

Among all the available renewable energy sources, solar is most abundant and an inexhaustible source of clean energy. Moreover, photovoltaic (PV) module technology has been widely used in modern industry to directly convert into electricity meet people's demands. The cell panel installation capacity are rapidly expanding Taiwan. In practice, many factors can cause fire hazards with PV systems, this danger increases as such systems scale up, high voltages 600 1000 V posing a greater risk than...

10.1109/icasi.2017.7988500 article EN 2017-05-01
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