A5021023755- Media, Gender, and Advertising
- Themes in Literature Analysis
- Gender Roles and Identity Studies
- Cancer Treatment and Pharmacology
- Cancer-related cognitive impairment studies
- Alzheimer's disease research and treatments
- Gender, Feminism, and Media
- Epigenetics and DNA Methylation
- Histone Deacetylase Inhibitors Research
- RNA and protein synthesis mechanisms
- Gender Studies in Language
- RNA Research and Splicing
- Bioinformatics and Genomic Networks
- CRISPR and Genetic Engineering
Columbia University
2022-2023
New York Genome Center
2023
University of Chicago
2021-2022
Abstract Introduction Variants in the tau gene ( MAPT ) region are associated with breast cancer women and Alzheimer's disease (AD) among persons lacking apolipoprotein E ε4 (ε4–). Methods To identify novel genes tau‐related pathology, we conducted two genome‐wide association studies (GWAS) for AD, one 10,340 ε4– Disease Genetics Consortium (ADGC) another 31 members (22 women) of a consanguineous Hutterite kindred. Results We identified associations AD MGMT variants ADGC (rs12775171, odds...
Alternative splicing is an essential mechanism for diversifying proteins, in which mature RNA isoforms produce proteins with potentially distinct functions. Two major challenges characterizing the cellular function of are lack experimental methods to specifically and efficiently modulate isoform expression computational tools complex design. To address these gaps, we developed methodically tested a strategy pairs RNA-targeting CRISPR/Cas13d system guide RNAs that span exon-exon junctions...
The manner in which gender is portrayed materials used to teach children conveys messages about people’s roles society. In this paper, we measure the gendered depiction of central domains social life 100 years highly influential children’s books. We make two main contributions: (1) find that portrayal these books reproduces traditional norms society, and (2) publish StoryWords 1.0, first word embeddings trained on such a large body literature. that, relative males, females are more likely be...
The way that people of different identities are portrayed in children's books can send subconscious messages about how positively or negatively children should think with those identities. These then shape the next generation's perceptions and attitudes people, which have important implications for belief formation resource allocation. In this paper, we make two contributions: (1) examine depiction race gender award-winning from last century, (2) consumption these relates to local beliefs....
The way that people of different identities are portrayed in children’s books can send subconscious messages about how positively or negatively children should think with those identities. These then shape the next generation’s perceptions and attitudes people, which have important implications for belief formation resource allocation. In this paper, we make two contributions: (1) examine depiction race gender award-winning from last century, (2) consumption these relates to local beliefs....
Increasing evidence suggests epidemiological and pathological links between Alzheimer disease (AD) breast cancer (BC). The 17q21 locus, including MAPT encoding tau, has been identified in genome-wide association studies (GWAS) for BC women AD among persons lacking the APOE ε4 allele (ε4-). We hypothesized that other genes involved tau-related pathology can be by GWAS stratified status.We conducted a ε4- (3,400 6,940 controls) Alzheimer's Disease Genetics Consortium (ADGC) datasets separately...