Alex George

ORCID: 0000-0002-4962-3917
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About
Contact & Profiles
Research Areas
  • MicroRNA in disease regulation
  • Carcinogens and Genotoxicity Assessment
  • Extracellular vesicles in disease
  • Cancer-related molecular mechanisms research
  • Heavy Metal Exposure and Toxicity
  • Craniofacial Disorders and Treatments
  • Mercury impact and mitigation studies
  • Sperm and Testicular Function
  • Immunotherapy and Immune Responses
  • Cleft Lip and Palate Research
  • DNA Repair Mechanisms
  • Circular RNAs in diseases
  • Cancer Cells and Metastasis
  • Drug-Induced Hepatotoxicity and Protection
  • Cancer Immunotherapy and Biomarkers
  • Pancreatic and Hepatic Oncology Research
  • Trace Elements in Health
  • Acute Lymphoblastic Leukemia research
  • Cancer, Hypoxia, and Metabolism
  • Retinoids in leukemia and cellular processes
  • Air Quality and Health Impacts
  • Congenital Anomalies and Fetal Surgery
  • Lysosomal Storage Disorders Research
  • Sexual Differentiation and Disorders
  • Medical and Biological Ozone Research

Jubilee Mission Medical College and Research Institute
2017-2025

Franklin W. Olin College of Engineering
2024

Christ University
2023

Creative Commons
2023

Government Medical College
2023

Cincinnati Children's Hospital Medical Center
2023

Canterbury Christ Church University
2020-2021

Vellore Institute of Technology University
2014-2021

JSS Academy of Higher Education and Research
2019

New Mexico Institute of Mining and Technology
2013

Heavy metal and metalloid poisoning in the environment food has piqued public’s interest since it poses significant hazards to ecological system human health. In food, several metals, including cadmium (Cd), lead (Pb), mercury (Hg), tin (Sn), manganese (Mn), aluminium (Al), metalloids, arsenic (As), antimony (Sb), selenium (Se), pose a severe threat It is of utmost importance detect even minute quantities these toxic elements this must be efficiently determined understand their risk. Several...

10.3390/su15021195 article EN Sustainability 2023-01-09

Despite advances in immunotherapy, non-small cell lung carcinoma (NSCLC) clinical success is limited, possibly due to substantial immunological alterations advanced cancer pa-tients. This study examines the immunomodulatory effects of exosomes derived from adeno-carcinoma (ADC) and squamous (SCC) on T cells. Methods: Exosomes were isolated A549 (lung adenocarcinoma), SKMES1 carcinoma), Jurkat-E6.1 (T cells). Exosome size morphology analysed by NTA TEM, respectively, while western blotting...

10.20944/preprints202501.2259.v1 preprint EN 2025-01-30

The increasing incidence of Type 2 diabetes mellitus globally has collaterally increased the diabetes-associated complications such as neuropathy. Oxidative stress induced DNA damage is one mechanisms implicated in pathogenesis diabetic complications. Here we aimed to evaluate extent patients with and without clinical neuropathy using Cytokinesis Block Micronucleus Cytome assay, a group South Indian population.The assay was performed lymphocyte cultures 42 type (22 20 neuropathy) age sex...

10.4103/0976-9668.149096 article EN Journal of Natural Science Biology and Medicine 2015-01-01

This study investigates the spread of pollutants from municipal waste into surrounding environment that could lead to environmental contamination, human health impacts, ecological damage, and economic consequences. Electrokinetically remediated lead-contaminated lateritic soil leachate collected an old Municipal Solid Waste (MSW) dumpsite were used in diffusion test investigate movement certain inorganic species through soil. The British Heavy (BSH) compactive effort was compact setup,...

10.47852/bonviewaaes42022566 article EN cc-by Archives of Advanced Engineering Science 2024-06-13

Workers in cement warehouses of Kerala are enduring long-standing exposure to dust, which is considered genotoxic.To evaluate the extent genotoxicity and cytotoxicity caused due dust among those working warehouses.The study included 82 warehouse workers age-matched individuals with no dust. Exfoliated buccal micronucleus cytome assay (BMCyt) was performed analyze genotoxic cytotoxic effects by inhalation dust.The frequency various end markers (micronucleated cells [2-fold increase, p<0.001],...

10.15171/ijoem.2020.1744 article EN The International Journal of Occupational and Environmental Medicine 2020-01-01

Head and neck cancers (HNC) are extremely complex disease types it is likely that chromosomal instability involved in the genetic mechanisms of its genesis. However, there little information regarding background levels chromosome these patients. In this pilot study, we examined spontaneous short-term lymphocyte cultures (72 hours) from 72 study subjects - 36 newly diagnosed HNC squamous cell carcinoma patients healthy ethnic controls. We estimated (CIN) using aberration (CA) analysis nuclear...

10.7314/apjcp.2014.15.3.1119 article EN cc-by Asian Pacific Journal of Cancer Prevention 2014-02-01
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