Markus Brinkmann

ORCID: 0000-0002-4985-263X
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About
Contact & Profiles
Research Areas
  • Environmental Toxicology and Ecotoxicology
  • Toxic Organic Pollutants Impact
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Effects and risks of endocrine disrupting chemicals
  • SARS-CoV-2 detection and testing
  • Microplastics and Plastic Pollution
  • Aquaculture disease management and microbiota
  • Aquaculture Nutrition and Growth
  • Biosensors and Analytical Detection
  • Pesticide and Herbicide Environmental Studies
  • Fish Ecology and Management Studies
  • Microbial Community Ecology and Physiology
  • Urban Stormwater Management Solutions
  • Gut microbiota and health
  • Heavy metals in environment
  • Environmental DNA in Biodiversity Studies
  • Mercury impact and mitigation studies
  • Per- and polyfluoroalkyl substances research
  • Advanced biosensing and bioanalysis techniques
  • Metabolomics and Mass Spectrometry Studies
  • Environmental Science and Water Management
  • SARS-CoV-2 and COVID-19 Research
  • Smart Materials for Construction
  • Reproductive biology and impacts on aquatic species
  • Water Quality and Pollution Assessment

University of Saskatchewan
2016-2025

Global Institute for Water Security
2018-2025

Canmore Museum and Geoscience Centre
2024

Medical University of Vienna
2024

Hygiene-Institut des Ruhrgebiets
2022

Park Plaza Hospital
2022

RWTH Aachen University
2010-2019

N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine-quinone (6PPD-quinone), a transformation product of the rubber tire antioxidant 6PPD, has recently been identified as chemical responsible for urban runoff mortality syndrome in coho salmon, with median lethal concentration (LC50) <0.1 μg/L. Subsequent studies have failed to confirm comparable sensitivity other fish species. Here, we investigated acute toxicity 6PPD-quinone rainbow trout, brook Arctic char, and white sturgeon. Fish were...

10.1021/acs.estlett.2c00050 article EN Environmental Science & Technology Letters 2022-03-02

Recent findings that 2-anilo-5-[(4-methylpentan-2-yl)amino]cyclohexa-2,5-diene-1,4-dione (6PPD-quinone), the transformation product of a common tire rubber antioxidant, is acutely toxic in stormwater-impacted streams has highlighted need for better understanding contaminants urban runoff. This study represents one first reports 6PPD-quinone and other rubber-derived compounds stormwater snowmelt cold-climate Canadian city (Saskatoon, 2019–2020). Semiquantification five target compounds,...

10.1021/acs.estlett.1c00682 article EN cc-by-nc-nd Environmental Science & Technology Letters 2021-09-22

N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine-quinone (6PPD-quinone), a rubber tire oxidation product found in road runoff, is highly and acutely toxic to selected salmonids including coho salmon, brook trout, rainbow trout but not other fish species invertebrates studied date. Sensitive displayed increased ventilation gasping, suggesting possible impact on respiration. Here, adherent cell lines RTL-W1 RTgill-W1 were exposed 5–80 μg/L 6PPD-quinone, cytotoxicity, oxygen consumption rate...

10.1021/acs.estlett.2c00431 article EN Environmental Science & Technology Letters 2022-08-04

N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine-quinone (6PPD-Q) is a rubber-tire derivative which leaches into surface waters from roadway runoff, tire particles and has been identified as possible driver of urban runoff mortality syndrome in coho salmon. Sensitivity to this toxicant highly variable across fish species life stages. With environmental concentrations meeting or exceeding toxicity thresholds sensitive fishes, the potential for ecologically relevant effects significant....

10.1021/acs.est.4c09090 article EN Environmental Science & Technology 2025-01-03

A critical review of the last 25 years dioxin policy in Elbe river catchment is presented along seven main theses River Basin Community (RBC)-Elbe background document "Pollutants" for Management Plan 2016–2021. In this period, polychlorinated dibenzodioxins/-furans (PCDD/Fs) and dioxin-like biphenyls (dl-PCBs) will play a major role: (i) as new priority substances which environmental quality standards (EQSs) need to be derived (Directive 2013/39/EC); (ii) search innovative solutions sediment...

10.1186/s12302-016-0075-8 article EN cc-by Environmental Sciences Europe 2016-03-29

Heterocyclic aromatic hydrocarbons (hetero-PAHs) are increasingly studied at contaminated sites; especially former industrial facilities where coal tar-oil was handled, e.g., wood treatment plants, high concentrations of hetero-PAHs frequently detected in groundwater plumes. In previous studies, fractions with estrogenic activity contained and their hydroxylated metabolites. To evaluate this preliminary evidence, selected were screened for lyticase yeast estrogen screen (LYES) ER CALUX. All...

10.1021/es405731j article EN Environmental Science & Technology 2014-04-11

Microplastics (MPs) are ubiquitous and persistent pollutants, have been detected in a wide variety of media, from soils to aquatic systems. MPs, consisting primarily polyethylene, polypropylene, polyacrylamide polymers, recently found 12% samples honey collected Ecuador. Recently, MPs also identified bees apiaries Copenhagen, Denmark, as well nearby semiurban rural areas. Given these documented exposures, assessment their effects is critical for understanding the risks MP exposure bees....

10.3390/toxics9050109 article EN cc-by Toxics 2021-05-15

There are no standardized protocols for quantifying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in wastewater to date, especially population normalization. Here, a pipeline was developed, applied, and assessed quantify SARS-CoV-2 key variants of concern (VOCs) RNA at Saskatoon, Canada. Normalization approaches using recovery ratio extraction efficiency, parameters, or indicators were by comparing daily numbers new cases. Viral load positively correlated with cases reported...

10.1021/acsestwater.1c00349 article EN public-domain ACS ES&T Water 2022-02-23

The potential to bioconcentrate is generally considered be an unwanted property of a substance. Consequently, chemical legislation, including the European REACH regulations, requires industry provide bioconcentration data for chemicals that are produced or imported at volumes exceeding 100 tons per annum if there concern substance persistent, bioaccumulative, and toxic. For filling existing gap levels below this stipulated volume, without need additional animal experiments,...

10.1021/acs.est.5b06158 article EN publisher-specific-oa Environmental Science & Technology 2016-01-21
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