A5014829337- Gastrointestinal motility and disorders
- Gastroesophageal reflux and treatments
- Diet and metabolism studies
- Esophageal and GI Pathology
- Dysphagia Assessment and Management
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Infant Health and Development
- Clinical Nutrition and Gastroenterology
- Congenital gastrointestinal and neural anomalies
- Gastrointestinal disorders and treatments
- Inflammatory Bowel Disease
- Cardiovascular Syncope and Autonomic Disorders
- Microscopic Colitis
- Intestinal Malrotation and Obstruction Disorders
- Intestinal and Peritoneal Adhesions
- Pelvic floor disorders treatments
- Esophageal Cancer Research and Treatment
- Phonocardiography and Auscultation Techniques
- Regulation of Appetite and Obesity
- Child Nutrition and Feeding Issues
- Diverticular Disease and Complications
- Celiac Disease Research and Management
- Vagus Nerve Stimulation Research
- Acupuncture Treatment Research Studies
University of Southern California
2013-2023
Clínica Las Condes
2016
Mayo Clinic in Arizona
2016
Gastro Obeso Center
2016
Creative Research Enterprises (United States)
2016
Cedars-Sinai Medical Center
2006-2015
Southern California University for Professional Studies
2012-2014
Ronald Reagan UCLA Medical Center
2013
University of Hawaiʻi at Mānoa
2013
Loma Linda University
2013
OBJECTIVE: Although tests of anorectal function are useful in the assessment defecation disorders, there is inadequate and inconsistent information regarding normative data. Also, discrepancies manometric techniques data interpretation. Our aim was to perform a comprehensive evaluation healthy adults. METHODS: We used 6-mm diameter probe containing six radially arrayed microtransducers, 4-cm-long latex balloon for performing manometry 45 subjects who were controlled gender age. Sequentially,...
Colon transit (CT) measurements are used in the management of significant constipation. The radiopaque marker (ROM) method provides limited information.We proposed to validate wireless motility capsule (WMC), that measures pH, pressure and temperature, ROM measurement CT patients with symptomatic constipation evaluated at multiple centers. Of 208 recruited, 158 eligible underwent simultaneous colonic time (CTT) using (Metcalf method, cut off for delay >67 h), WMC (cutoff >59 h). study was...
Pouchitis often is diagnosed based on symptoms alone. However, increased stool frequency, urgency, and abdominal pain could be due to a condition resembling irritable bowel syndrome. This study was designed assess the etiology of using Disease Activity Index (PDAI).Symptoms, endoscopy, histology were assessed in 61 consecutive symptomatic patients with ulcerative colitis after ileal pouch-anal anastomosis. defined as PDAI score > or = 7, cuffitis endoscopic histological inflammation rectal...
Lower esophageal sphincter (LES) electrical stimulation therapy (EST) has been shown to improve outcome in gastroesophageal reflux disease (GERD) patients at 1 year. The aim of this open-label extension trial (NCT01578642) was study the 2-year safety and efficacy LES-EST GERD patients.GERD responsive partially proton pump inhibitors (PPI) with off-PPI health-related quality life (HRQL) ≥20, 24-hour pH ≤4.0 for >5% time, hiatal hernia ≤3 cm, esophagitis LA grade C or lower participated trial....
A high frequency of celiac disease is reported in patients with collagenous colitis. Limited information available on the lymphocytic The aim our study was to determine prevalence microscopic colitis (collagenous and colitis). Patients were identified from a pathology registry 1987 1999. Pathology reports medical records reviewed for previous small bowel biopsies and/or serology. We 113 colitis, 46 underwent biopsy Of these, 27 had (63% female; age, 58.6 +/- 16.2 years) 19 (79% 61.8 13.6...
In patients with gastroesophageal reflux disease (GERD), temporary electrical stimulation of the lower esophageal sphincter (LES) increases LES pressure without interference relaxation. The aim current study was to investigate safety and efficacy long term therapy (LES-EST), using a permanently implanted stimulator for treatment GERD.Patients GERD who were at least partially responsive proton pump inhibitors (PPIs) had hiatal hernia ≤ 3 cm esophagitis Los Angeles Grade A, B, or C included in...
The study of human colonic motility under physiological conditions has proved to be an elusive goal. We have used a two-stage pernasal technique position sensors in the colon for prolonged monitoring freely ambulant subjects. Nine healthy volunteers were studied total recording time 263 h, each lasting between 13 and 48 (mean 29) h. Motor activity all regions large bowel was characterized by scant irregular contractions with infrequent bursts that did not conform any pattern. No motor...
Background: The TANTALUS® System is an investigational device that consists of implantable pulse generator connected to gastric electrodes. system designed automatically detect when eating starts and only then deliver sessions electrical stimulation (GES) with pulses are synchronized the intrinsic antral slow waves. We report effect this type GES on weight loss glucose control in overweight/obese subjects 2 diabetes mellitus (T2DM). This study was conducted under a Food Drug...
Gastric electrical stimulation (GES) for gastroparesis has been in use more than a decade. Multiple publications, consisting almost entirely of open label single center studies, reported beneficial effect on symptoms, quality life and nutritional status. Some predictors better response to GES have lately identified, primarily diabetic etiology nausea vomiting as the predominant symptoms. However, individual remains difficult predict. The mechanism action poorly understood. Stimulation...