- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Musculoskeletal pain and rehabilitation
- Intracranial Aneurysms: Treatment and Complications
- Cervical and Thoracic Myelopathy
- Pelvic and Acetabular Injuries
- Meningioma and schwannoma management
- Scoliosis diagnosis and treatment
- Spinal Hematomas and Complications
- Vascular Malformations Diagnosis and Treatment
- Management of metastatic bone disease
- Traumatic Brain Injury and Neurovascular Disturbances
- Glioma Diagnosis and Treatment
- MicroRNA in disease regulation
- Medical Imaging and Analysis
- COVID-19 and healthcare impacts
- Cerebrospinal fluid and hydrocephalus
- Spinal Dysraphism and Malformations
- Cerebrovascular and Carotid Artery Diseases
- Anesthesia and Pain Management
- Extracellular vesicles in disease
- Global Health and Surgery
- Myofascial pain diagnosis and treatment
- Trauma and Emergency Care Studies
- Nerve Injury and Rehabilitation
Azienda Ospedaliera Sant'Andrea
2017-2024
Sapienza University of Rome
2017-2024
Azienda Ospedaliera S.Maria
2022
Creative Research Enterprises (United States)
2022
OBJECTIVE Lumbar spinal stenosis (LSS) is the most common disease in geriatric population, and characterized by a compression of lumbosacral neural roots from narrowing lumbar canal. LSS can result symptomatic elements, requiring surgical treatment if conservative management fails. Different techniques with or without fusion are currently options. The purpose this study was to provide description long-term clinical outcomes patients who underwent bilateral laminotomy compared total...
OBJECTIVE Over the last few decades, many surgical techniques for lumbar interbody fusion have been reported. The anterior-to-psoas (ATP) approach is theoretically supposed to benefit from advantages of both anterior and lateral approaches with similar complication rates, even in L5–S1. At this segment, (ALIF) requires retroperitoneal dissection retraction major vessels, whereas iliac crest does not allow transpsoas approach. This study aimed investigate clinical-radiological outcomes...
The typical traumatic thoracolumbar (TL) fracture in patients with ankylosing spondylitis (AS) is a hyperextension injury involving all three spinal columns, which associated unfavorable outcomes. Although consensus on the management of these highly unstable injuries missing, minimally invasive surgery (MIS) has been progressively accepted as treatment option, since it related to lower morbidity and mortality rates. This study aimed evaluate clinical radiological outcomes after percutaneous...
Study Design: This was a retrospective study of the clinical and radiologic outcomes traumatic thoracolumbar (TL) burst fractures. Objectives: We aimed to evaluate after 6 years follow-up 144 patients with monosegmental TL fractures treated percutaneous short-segment pedicle screw fixation, comparing two groups versus without placement an intermediate at fractured vertebra. Summary Background Data: Traumatic are most common vertebral fractures, especially junction (T10–L2). Minimally...
Background: Radiological evidence of adjacent segment disease (ASD) has been reported to have a prevalence more than 30% and several risk factors reported. The aim this study is evaluate the clinical radiological outcomes patients with symptomatic ASD treated stand-alone OLIF compare results posterior revision surgery cohort. Methods: This retrospective case-control study. Clinical-patient-reported were obtained at preoperative, postoperative final follow-up visits using Short Form (SF-36)...
Background: Normal pressure hydrocephalus (NPH) is characterized by the triad of dementia, gait disturbance and urinary incontinence, all potentially reversible following a ventriculoperitoneal shunt (VPS). This study aims to evaluate clinical outcomes shunting in normal new standardized protocol. Methods: designed according STROBE guidelines. Demographical, clinical, surgical radiological data were collected from May 2015 November 2019. Gait, balance incontinence based on NPH European scale...
Anterior cervical discectomy and fusion (ACDF) anterior corpectomy (ACCF) represent effective alternatives in the management of multilevel spondylotic myelopathy (CSM). A consensus on which these techniques should be used is still missing.The databases three centers were reviewed (January 2011-December 2018) for patients with three-level CSM, who underwent ACDF without plating or two-level ACCF expandable cage (VBRC) mesh (VBRM). Demographic data, surgical strategy, complications, implant...
Background: Standard oblique cages cannot cover endplates side-to-side, which is an important biomechanical factor for reducing the risk of cage subsidence and restoring correct segmental lordosis. The aim this study to evaluate radiological clinical results a new lumbar interbody fusion (OLIF) axially expandable cage. Methods: This prospective observational case-control study. From March 2018 June 2020, 28 consecutive patients with degenerative disease underwent ATP approach, insertion...
Lumbar spinal stenosis (LSS) is a common degenerative condition that occurs in the spine with increasing age. Clinically, LSS causes progressive reduction walking autonomy, resulting poor quality of life and impaired functional capacity. The aim this study was to evaluate clinical outcome elderly patients presenting associated comorbidities after 5-year follow-up who were treated an interspinous process device (IPD). Sixty > 75 years age symptomatic included. All IPD under local anesthesia....
In conclusion, we believe that unconventional measures are required to deal with emergencies.Although these may correspond suboptimal assistance for our patients, an effective compromise must be reached.Even though physical examination and clinical-radiological correlations fundamental parts of challenging profession, make do less has considered in special conditions, such as COVID-19 emergency.Medical workers health need preserved well patients' one, or even more.
OBJECTIVE The objective of this paper was to determine the interobserver reliability and intraobserver reproducibility AO Spine Upper Cervical Injury Classification System based on surgeon experience (< 5 years, 5–10 10–20 > 20 years) surgical subspecialty (orthopedic spine surgery, neurosurgery, "other" surgery). METHODS A total 11,601 assessments upper cervical injuries were evaluated System. Reliability scores obtained twice, with a 3-week time interval. Descriptive statistics...
Anderson type II odontoid fractures are severe conditions, mostly affecting elderly people (≥ 70 years old). Surgery can be performed as a primary treatment or in cases of failed conservative management. This study aimed to investigate how duration from injury surgery, well clinical, radiological, and surgical risk factors, may influence the union rate after anterior screw placement for fractures.
The biological heterogeneity of glioblastoma, IDH-wildtype (GBM, CNS WHO grade 4), the most aggressive type brain cancer, is a critical hallmark, caused by changes in genomic mutational asset and influencing clinical progression over time. understanding monitoring profile important not only to reveal novel therapeutic targets this set patients, but also ameliorate stratification subjects prognostic significance. As neurosurgery represents primary technique manage GBM, it utmost importance...
Minimally invasive spine surgery (MISS) has been progressively accepted as a useful approach for tumors. Recently released carbon-PEEK implants have already reported effective in open surgeries This study aimed to evaluate the feasibility, surgical, clinical and radiological outcomes of new percutaneous instrumentations tumors.This is prospective case-control observational study. Demographical, clinical, data were collected from May 2018 August 2019. Visual Analogue Scale back pain (VAS),...
Lumbar spinal stenosis (LSS) and low-grade degenerative spondylolisthesis are frequently associated with facet joint degeneration, considered the main cause of low back pain. Surgery is treatment choice in patients affected by LSS unresponsive to conservative treatment. The aim this study was evaluate clinical radiologic outcome treated posterior decompression transfacet fixation for single-level degeneration. A total 25 between May 2015 June 2016 radiologically demonstrated one-level...