A5067409794- Primary Care and Health Outcomes
- Chronic Disease Management Strategies
- Geriatric Care and Nursing Homes
- Frailty in Older Adults
- Healthcare Policy and Management
- Diabetes Management and Education
- Health Systems, Economic Evaluations, Quality of Life
- Health and Medical Research Impacts
- Health disparities and outcomes
- Nutrition and Health in Aging
- Retirement, Disability, and Employment
- Global Health Workforce Issues
- Plant Toxicity and Pharmacological Properties
- Irish and British Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Obstructive Sleep Apnea Research
- Healthcare innovation and challenges
- Breast Cancer Treatment Studies
- Telemedicine and Telehealth Implementation
- Health Policy Implementation Science
- Medical Malpractice and Liability Issues
- Health Sciences Research and Education
- Academic Writing and Publishing
- Immune Response and Inflammation
- Colorectal Cancer Screening and Detection
Flinders University
2015-2024
Medical Defence Union
2022
University Hospitals Plymouth NHS Trust
2022
United Arab Emirates University
2001-2021
Adelaide Institute for Sleep Health
2021
University of Florida
2008-2020
Israel Defense Forces Medical Corps
2018
Norwegian Armed Forces
2018
Birmingham Research Park
2018
Tufts University
2018
PURPOSE To evaluate the prognostic importance of immunocytochemically determined c-erbB-2 overexpression in primary tumors patients with breast cancer. PATIENTS AND METHODS Primary from 1,506 cancer (760 node-negative and 746 node-positive) who were treated International (Ludwig) Breast Cancer Study Group Trial V studied. Node-negative allocated randomly to either a single cycle perioperative chemotherapy (PeCT) or no adjuvant treatment, node-positive received prolonged (with tamoxifen for...
To determine the extent that muscle mass is predictive of strength in elderly, anthropomorphic estimates area and impedance measurements peak isometric were obtained a relatively healthy older population over 65 years age (mean = 71.7; n 218). Midarm correlated strongly with upper arm (r 0.68, P < 0.0001) while midthigh had much lower correlation thigh 0.29, 0.0001). These calculations also include bone area. Lean body calculated by bioelectric highly cumulative measured summing all...
<h3>Background</h3> To address the growing burden of disease and long waiting lists for sleep services, a simplified two-stage model was developed validated identifying obstructive apnoea (OSA) in primary care using screening questionnaire followed by home monitoring. <h3>Methods</h3> 157 patients aged 25–70 years attending their physician any reason at six clinics rural metropolitan regions South Australia participated. The first 79 formed development group next 78 validation group. A from...
<h3>Importance</h3>Due to increasing demand for sleep services, there has been growing interest in ambulatory models of care patients with obstructive apnea. With appropriate training and simplified management tools, primary physicians are ideally positioned take on a greater role diagnosis treatment.<h3>Objective</h3>To compare the clinical efficacy within-trial costs model relative that specialist centers.<h3>Design, Setting, Patients</h3>A randomized, controlled, noninferiority study...
The prognostic significance of histologic tumor grade has been evaluated in 1537 women entered into the Ludwig Trials I-IV adjuvant therapy for node-positive breast cancer. Tumor was determined on review primary sections by two central pathologists using a modification Bloom and Richardson grading system. 5-year overall survival rates (±SE) were: Grade 1, 86% ± 2; 2, 70% 3, 57% 2 (P <0.0001). This difference seen both premenopausal <0.0001) postmenopausal women. Significant differences...
Abstract Background The emergence of the COVID-19 pandemic has raised concerns about potential decrease in access and utilisation general practice services its impact on patient care. In March 2020, Australian Government introduced telehealth to ensure that people more vulnerable do not delay routine care from their practitioners. Evidence patients’ experience is scarce. This study aimed investigate with by patients at high risk poor health outcomes during pandemic. Methods Semi-structured...
A pilot study was conducted to investigate the feasibility and effectiveness of behavioral activation (BA) therapy for veterans with posttraumatic stress disorder (PTSD). Eleven seeking treatment at a Veterans Administration outpatient PTSD clinic were enrolled in protocol, consisting 16-weekly individual sessions BA. Nine completed one participant 15 sessions, dropped out after session. Clinician-rated symptom severity showed significant pre- posttreatment improvement associated moderate...
PURPOSE An international trial (formerly Ludwig Trial V) has been conducted in 1,275 subjects to ascertain if perioperative chemotherapy is beneficial for node-negative breast cancer patients and identify subgroups of who benefit from this therapy. PATIENTS AND METHODS Node-negative were randomized receive either one cycle or no adjuvant treatment. A detailed pathology review was 1,203 the enrolled. Stepwise Cox regression analysis used search factors predicting chemotherapeutic...
The Trauma Hemostasis and Oxygenation Research (THOR) Network has developed a consensus statement on the role of permissive hypotension in remote damage control resuscitation (RDCR). A summary evidence follows THOR position topic. In RDCR, burden time care patients suffering from noncompressible hemorrhage affects outcomes. Despite lack published evidence, based clinical experience expertise, it is Network's opinion that increase prehospital leads to an increased shock, which poses greater...
Abstract Background This study estimated the prevalence of evidence-based care received by a population-based sample Australian residents in long-term (LTC) aged ≥ 65 years 2021, measured adherence to clinical practice guideline (CPG) recommendations. Methods Sixteen conditions/processes amendable estimating at population level were identified from data and CPGs. Candidate recommendations ( n = 5609) extracted 139 CPGs which converted indicators. National experts each condition rated...
Rats display a marked sex difference in the oxidation of pyrrolizidine alkaloid senecionine, especially with respect to N-oxidation. This was largely eliminated following treatment dexamethasone. These observations suggested potential involvement male-specific cytochrome P-450 UT-A and PCN-E metabolism this alkaloid. Reconstituted rat exhibited high rate N-oxidation (15 nmol min-1 P-450-1) which is almost 3-fold higher than turnover number observed male liver microsomes. In contrast,...
Drapanas, Theodore M.D.; Woolverton, William C. Reeder, Jack W. Reed, Richard L. Weichert, Rudolph F. M.D. Author Information
OBJECTIVE: Mini‐Mental State Examination (MMSE) scores are associated with age, education, and ethnicity. The objective of this research was to determine the relationship between MMSE literacy. DESIGN: Cross‐sectional. SETTING: A Community population in Tucson, Arizona. PARTICIPANTS: Senior citizens public assistance housing. MEASUREMENTS: score, reading level, socio‐demographic variables. MAIN RESULTS: total 214 subjects were tested. mean age 72.3 (±8.01), education level 10.3 years (range...
Observant Muslims substantially alter their normal routines, including daytime fasting and day-night activity patterns during the month of Ramadan.It is unknown whether observing religious practices Ramadan impacts negatively on somnolence, a factor known to impair learning.A cross-sectional survey measuring self-reported sleep time Epworth Sleepiness Scale observant Muslim medical students before, during, after Ramadan.There was no significant variation in score pre-Ramadan (10.04 +/-...
To determine the validity of Pra instrument in predicting use health-related services by older enrollees a managed care plan.Cohort study. At baseline, survey was administered mail. Responses were entered into formula to estimate each person's probability using heavily future. The subjects' during following year monitored through claims submitted their organization.Urban and suburban areas Southern California.Persons aged 65 years enrolled Medicare risk health plan (n = 6802).Baseline data...
<i>Background:</i> Studies of risk factors for clinically significant pressure ulcers in the hospital have been limited by small number study subjects that develop ulcers, resulting contradictory findings regarding some factors. <i>Objective:</i> To determine if three (low serum albumin level, fecal incontinence, and confusion) were when tested a large data set. <i>Methods:</i> The design was longitudinal cohort using collected as component multi-site...