A5016493622- Endodontics and Root Canal Treatments
- Bone and Dental Protein Studies
- Bone Tissue Engineering Materials
- Periodontal Regeneration and Treatments
- Dental Implant Techniques and Outcomes
- Bone Metabolism and Diseases
- Neuroscience and Neuropharmacology Research
- Fibroblast Growth Factor Research
- Photoreceptor and optogenetics research
- Hydrogen's biological and therapeutic effects
- Oral microbiology and periodontitis research
- Laser Applications in Dentistry and Medicine
- Proteoglycans and glycosaminoglycans research
- Dental Anxiety and Anesthesia Techniques
- Calpain Protease Function and Regulation
- Autophagy in Disease and Therapy
- Bone health and treatments
- Calcium Carbonate Crystallization and Inhibition
- Dental Trauma and Treatments
- Wound Healing and Treatments
- Microfluidic and Capillary Electrophoresis Applications
- Vanadium and Halogenation Chemistry
- Regulation of Appetite and Obesity
- Estrogen and related hormone effects
- Connexins and lens biology
Stomatology Hospital
2015-2024
Sun Yat-sen University
2004-2024
Hospital of Stomatology, Sun Yat-sen University
2015-2024
Key Laboratory of Guangdong Province
2018
Chongqing Medical University
2017
Stomatological Hospital of Chongqing Medical University
2017
The Affiliated Yongchuan Hospital of Chongqing Medical University
2017
Johannes Gutenberg University Mainz
2012-2014
Hebei Medical University
2000
Self-generated neuronal activity originating from subcortical regions drives early spontaneous motor activity, which is a hallmark of the developing sensorimotor system. However, neural patterns and role primary cortex (M1) in these movements are still unknown. Combining voltage-sensitive dye imaging (VSDI) with simultaneous extracellular multielectrode recordings postnatal day 3 (P3)–P5 rat somatosensory (S1) M1 vivo, we observed that tactile forepaw stimulation induced spindle bursts S1...
A number of bone-filling materials containing calcium (Ca(2+) ) and phosphate (P) ions have been used in the repair periodontal bone defects; however, effects that local release Ca(2+) P has on biological reactions are not fully understood. In this study, we investigated various levels proliferation, osteogenic differentiation mineralization human ligament cells (hPDLCs).The hPDLCs were obtained using an explant culture method. Defined concentrations ratios ionic to inorganic added standard...
Long-term potentiation (LTP) is important for the activity-dependent formation of early cortical circuits. In neonatal rodent barrel cortex, LTP has been studied only <i>in vitro</i>. We combined voltage-sensitive dye imaging with extracellular multielectrode recordings to study whisker stimulation-induced in whisker-to-barrel cortex pathway rat vivo</i>. Single stimulation at 2 Hz 10 min induced an age-dependent expression postnatal day (P) 0 P14 rats, strongest P3–P5. The magnitude was...
Calcium ions (Ca2+) are a major constituent of most pulp-capping materials and have an important role in the mineralization human dental pulp cells (hDPCs). A previous study by our group has shown that increased levels Ca2+ can promote hDPC-mediated long-term cultures (21 days). However, initiation occurs early stage osteogenic inductive culture, effects on hDPCs short-term (five days) not been studied detail. Furthermore, underlying mechanism which stimulates remained controversial. strong...
The exact phenotype of human periodontal ligament cells (hPDLCs) remains a controversial area. Basic fibroblast growth factor (FGF‑2) exhibits various functions and its effect on hPDLCs is also controversial. Therefore, the present study examined FGF‑2 osteoblastic with or without osteogenic inducers (dexamethasone β‑glycerophosphate). was added to defined culture medium inductive medium. Cell proliferation, differentiation mineralization were measured. selected markers, Runx2, collagen type...
The aim of this study was to evaluate the effect porous biphasic calcium phosphate (BCP) scaffolds on proliferation and osteoblastic differentiation human periodontal ligament cells (hPDLCs) in presence absence osteogenic inducer (L-ascorbic acid, dexamethasone β-glycerophosphate). cell growth within inducers studied by counting kit-8 (CCK-8) assay scanning electron microscopy (SEM). Alkaline phosphatase (ALP) activity markers hPDLCs BCP were examined inducers. number less than that cultured...
Abstract Aim The purpose of this study was to investigate the role calcium‐sensing receptor (CaSR) in angiogenic differentiation lipopolysaccharide (LPS)‐treated human dental pulp cells (hDPCs). Methodology LPS‐induced hDPCs were cultured medium with different combinations CaSR agonist R568 and antagonist Calhex231. cell proliferation, migration, capacity measured by Cell Counting Kit‐8 (CCK‐8), scratch wound healing, tube formation assays, respectively. Enzyme‐linked immunosorbent assay...
The repair of bone defects that result from periodontal diseases remains a clinical challenge for therapy. β-tricalcium phosphate (β-TCP) ceramics are biodegradable inorganic substitutes with components similar to those bone. Demineralized matrix (DBM) is an acid-extracted organic derived sources consists the collagen and proteins A few studies have documented effects DBM on proliferation osteogenic differentiation human ligament cells (hPDLCs). aim present study was investigate elements...
Objective In this study, we constructed a composite by combining the human dental follicle cell sheet and manual drilled porous decalcified dentin matrix that was used to construct ectopic tissue‐engineered periodontal ligament‐like tissues in renal capsules of nude mice. Materials methods Human cells were harvested from lower third molars then embedded into temperature‐sensitive culture dish. These placed frozen sheets induced 50 g/ml ascorbic acid. This established “sandwich structure”...
OBJECTIVE To compare the sealing ability and fracture resistance of roots endodontically treated with bonded unbonded filling materials. METHODS One hundred fifteen straight mandibular premolar teeth single canal were divided randomly into 6 experimental groups, 15 samples each, 3 control groups. The was evaluated using a glucose quantitative microleakage mode tested by universal testing machine. RESULTS results showed that material had lowest value while highest in all There significant...