A5019388466- Animal Behavior and Welfare Studies
- Effects of Environmental Stressors on Livestock
- Genetic and phenotypic traits in livestock
- Reproductive Physiology in Livestock
- Animal Disease Management and Epidemiology
- Genetic Mapping and Diversity in Plants and Animals
- Food Supply Chain Traceability
- Dermatology and Skin Diseases
- Agriculture and Farm Safety
- Animal Nutrition and Physiology
- Meat and Animal Product Quality
- Ruminant Nutrition and Digestive Physiology
- Milk Quality and Mastitis in Dairy Cows
- Plant and fungal interactions
University of Liverpool
2021-2025
Lameness is a major welfare challenge facing the dairy industry worldwide. Monitoring herd lameness prevalence, and early detection therapeutic intervention are important aspects of control in herds. The objective this study was to evaluate performance commercially available video surveillance system for automatic cattle (CattleEye Ltd).This achieved by first measuring mobility score agreement between CattleEye two veterinarians (Assessor 1 Assessor 2), second, investigating ability detect...
Early detection and prompt treatment of lame cows are crucial for proactive lameness management. This study aimed to evaluate a fully automated 2-dimensional imaging system real-time using artificial intelligence. Data were collected from 11 dairy farms in the UK Four trained veterinarians performed 42 mobility scoring sessions 0-3 4-grade system, with scores 2 3 representing lameness. On each session, individual weekly average calculated. resulted 40,116 paired human (HMS) generated...
Abstract Digital dermatitis (DD) is an endemic infectious hoof disease causing lameness in dairy cattle. The aim of the present study was to investigate genetic profile DD development using phenotypic and genotypic data on 2192 Holstein cows. feet each cow were clinically examined four times: pre-calving, shortly after calving, near peak milk production, late lactation. Presence or absence proportion healthy per constituted two phenotypes study. For phenotype timepoint clinical examination,...
<title>Abstract</title> Claw horn disruption lesions (CHDL) are painful non-infectious foot with significant animal welfare and socioeconomic impacts on the dairy industry. Lameness caused by CHDL is main cause of involuntary culling, considerably reduces milk production, constitutes a major concern directly sustainability sector through increased costs, veterinary intervention raising replacement cattle environmental implications. As complex heritable polygenic disease, better understanding...
Lameness in dairy cattle is primarily caused by foot lesions including the claw horn (CHL) of sole haemorrhage (SH), ulcers (SU), and white line disease (WL). This study investigated genetic architecture three CHL based on detailed animal phenotypes susceptibility severity. Estimation parameters breeding values, single-step genome-wide association analyses, functional enrichment analyses were performed.The studied traits under control with a low to moderate heritability. Heritability...
The objective of this study was to investigate the association between (sub)clinical mastitis (CM) in first 30 days milk (DIM) and presence sole ulcers (SU) later lactation.Holstein cows heifers were examined for haemorrhage SU before calving, 14 postcalving early lactation (after DIM). CM episodes somatic cell counts (SCC) measurements obtained from farm records. Multivariable logistic regression used data analysis.Odds 2.44 times greater (95% confidence interval [CI] 0.97-5.54) that had...
Sole hemorrhage and sole ulcers, referred to as lesions, are important causes of lameness in dairy cattle. The objective this study was estimate the genetic parameters a novel trait reflecting how well cows recovered from lesions correlation with overall susceptibility lesions. A cohort Holstein prospectively enrolled on 4 farms assessed at timepoints: before calving, immediately after early lactation, late lactation. At each timepoint, were recorded claw level by veterinary surgeons used...
Abstract Background The objective of this study was to evaluate the benefits administering ketoprofen cows suffering from active digital dermatitis (DD). Methods 158 presented with DD (M1, M2 or M4.1 stage) were randomly allocated either control treatment group. All treated topical application oxytetracycline spray. group also received an intramuscular injection (3 mg/kg, Ketofen 10%, Ceva Animal Health). Cows mobility scored just before they and then again one week later. Information...
Foot characteristics have been linked to the development of sole lesions (sole hemorrhage and ulcers) white line lesions, also known as claw horn disruption (CHDL). The objective this study was examine association anatomy temperature with CHDL. A cohort 2,352 cows prospectively enrolled from 4 UK farms assessed at 3 time points: before calving (T1-precalving), immediately after (T2-calving), in early lactation. At each point body condition score recorded, a thermography image foot taken for...
Abstract Background This study aimed to determine the association between lameness advantage genetic index and four outcomes: sole haemorrhage (SH), ulcers (SU), white line lesions (WL), during mobility scoring. Methods We enrolled 2352 Holstein cows from predominantly housed dairy herds in UK. Cows were scored foot recorded at time points before calving late lactation. genotyped indexes assigned each cow following national evaluations. Lameness records matched for 2107 cows. Four separate...
Sole hemorrhage and sole ulcers, referred to as lesions, are important causes of lameness in dairy cattle. We aimed compare the serum metabolome cows that developed lesions early lactation with remained unaffected. prospectively enrolled a cohort 1,169 Holstein from single herd assessed animals at 4 time points: before calving, immediately after lactation, late lactation. were recorded by veterinary surgeons each point, samples collected first 3 points. Cases defined presence further...
Monitoring body condition score (BCS) is a useful management tool to estimate the energy reserves of an individual cow or group cows. The aim this study was develop and evaluate performance fully-automated 2D imaging system using machine learning algorithm generate real-time BCS for dairy Two separate data sets were used training testing. set included 34,150 manual (MAN_BCS) assigned by 5 experienced veterinarians during 35 visits in 7 farms. Ordinal regression methods deep architecture when...
The digital cushion is linked to the development of claw horn lesions (CHL) in dairy cattle. objectives this study were (1) estimate genetic parameters for thickness (DCT), (2) correlation between DCT and CHL, (3) identify candidate genes associated with DCT. A cohort 2,352 Holstein cows prospectively enrolled on 4 farms assessed at time points: before calving, immediately after early lactation, late lactation. At each point, CHL was recorded by veterinary surgeons, ultrasonographic images...
Digital dermatitis (DD) is a polybacterial disease endemic to most UK dairy farms. It poses major financial and welfare threat characterized by high incidence recurrence rates. We aimed investigate the association between estimated breeding value for resistance digital dermatitis, Dermatitis Index (DDI) frequency of DD, heel horn erosion (HHE), interdigital hyperplasia (IH) in population Holstein cows. enrolled genotyped 2,352 cows from 4 farms prospective cohort study. Foot lesion records...
Key factors such as stage of lactation, parity and body fat reserves have been associated with the digital cushion thickness, however, there are discrepancies between results previously published studies. The objective this study was to examine association reserves, parity, lesion incidence thickness (DCT) in a large cohort intensively monitored cows. Across 4 UK farms, 2,352 cows were prospectively enrolled assessed at time points; before calving (T1-Precalving), immediately post-calving...
This study aimed to investigate the transcriptomic signature of claw horn disruption lesions (CHDL) in peripheral blood leucocytes (PBL) dairy cattle. The PBL transcriptome 24 cows, twelve cows susceptible (cases) and 12 resistant (controls) CHDL were compared. Total RNA was extracted for sequencing using Illumina technology. Raw reads mapped cattle genome (ARS-UCD1.2) STAR aligner differentially expressed gene (DEG) analysis performed DESeq2. Eighty-eight DEG genes found between cases...
Lameness in dairy cattle is primarily caused by foot lesions including sole haemorrhage (SH) and ulcers (SU). This study investigated the genetic architecture of SH SU different lactation stages based on accurate phenotyping, parameter estimation, genome-wide association (GWA) functional enrichment analyses. Foot lesion records were collected from 2,353 Holstein cows four herds at time-points: prior to calving, immediately after early lactation, late stages. Heritability estimates 0.11-0.20...