Melek Güra Çelik

ORCID: 0000-0002-5227-0462
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About
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Research Areas
  • Anesthesia and Sedative Agents
  • Anesthesia and Pain Management
  • Intensive Care Unit Cognitive Disorders
  • Cardiac, Anesthesia and Surgical Outcomes
  • Nausea and vomiting management
  • Spinal Dysraphism and Malformations
  • Nosocomial Infections in ICU
  • Tracheal and airway disorders
  • Airway Management and Intubation Techniques
  • Family and Disability Support Research
  • Esophageal and GI Pathology
  • Respiratory Support and Mechanisms
  • Anesthesia and Neurotoxicity Research
  • Injury Epidemiology and Prevention
  • Boron Compounds in Chemistry
  • Parkinson's Disease and Spinal Disorders
  • Meningioma and schwannoma management
  • Intraoperative Neuromonitoring and Anesthetic Effects
  • Optical Imaging and Spectroscopy Techniques
  • Traumatic Brain Injury Research
  • Traumatic Ocular and Foreign Body Injuries
  • Voice and Speech Disorders
  • Therapeutic Uses of Natural Elements
  • Cerebrospinal fluid and hydrocephalus
  • Climate Change and Health Impacts

Istanbul Medeniyet University
2013-2022

Medeniyet Üniversitesi Göztepe Eğitim ve Araştırma Hastanesi
2007-2022

Ministry of Health
2011

What is known and objective The most appropriate sedative agent for conscious sedation in minor hysteroscopic surgeries still unclear. Dexmedetomidine a analgesic agent, may be outpatient procedures. aim of our study was to compare the sedative, hemodynamic effects dexmedetomidine vs propofol combination with fentanyl midazolam patients undergoing hysteroscopy surgery. Methods Sixty surgery were randomized receive either (n = 30) or groups. infused at 1 µg/kg 10 minutes followed by 0.7...

10.1111/jcpt.12793 article EN Journal of Clinical Pharmacy and Therapeutics 2019-01-11

In the present study, we aimed to assess rate and effect of device-associated nosocomial infections (DANIs), as well antibiotic resistance, in medical-surgical intensive care unit (ICU) a research training hospital Turkey, compare our results with those reported by National Nosocomial Infections Surveillance (NNIS) system International Infection Control Consortium (INICC). A total 509 patients were followed up within 1-year period from 1 November 2007 2008. The patient days 4,087, number...

10.7883/yoken.63.95 article EN Japanese Journal of Infectious Diseases 2010-03-31

The aim of the study was to evaluate comparative effects propofol infusion versus sevoflurane for maintenance anesthesia with respect hemodynamics, recovery characteristics, nausea and vomiting in patients undergoing percutaneous nephrolithotomy.Forty American Society Anesthesiologists physical status I-II patients, aged between 22 65 years were randomly divided receive either intravenous (group P) or S). Cardiovascular variables, peripheral oxygen saturation (SpO2), end-tidal carbon dioxide...

10.4097/kjae.2013.64.3.223 article EN cc-by-nc Korean journal of anesthesiology 2013-01-01

Recently, Iskandar et al described "Chiari Zero malformation" to characterize some kind of syringomyelia that exhibits classic Chiari-type symptoms with little no herniation, but there is dilemma about whether it actually present.We presented a 38-year-old-man diagnosis cervical syringomyelia.In his neurological examination, was monoparesia at the left leg together hypoesthesia below thoracal 7.He had initially been treated syringopleural shunting successfully.Nine months after surgery,...

10.5137/1019-5149.jtn.2705-09.1 article EN Turkish Neurosurgery 2009-01-01

What is known and objective Adenotonsillectomies are common surgical procedures performed under general anaesthesia in childhood. Post-operative pain agitation complications associated with this procedure. We compared the effects of dexmedetomidine tramadol on post-operative pain, agitation, haemodynamic parameters, extubation quality patients undergoing an adenotonsillectomy using sevoflurane as anaesthetic agent. Methods Sixty paediatric who had undergone were included study. The...

10.1111/jcpt.13080 article EN Journal of Clinical Pharmacy and Therapeutics 2019-12-04

Optimal sedation and analgesia are of key importance in intensive care. The aim this study was to assess the quality sedoanalgesia outcome parameters regimens containing midazolam either fentanyl or remifentanil. A prospective, randomized, open-label, controlled trial carried out ICU unit a large teaching hospital Istanbul over 9-month period. Thirty-four patients were randomly allocated receive remifentanil-midazolam regimen ( R group, ) fentanyl-midazolam F ). strong correlation between...

10.1155/2011/650320 article EN cc-by Pain Research and Treatment 2011-07-02

Ventilator-associated pneumonia (VAP) is a frequently occurring nosocomial infection in ICU patients and has been associated with increased morbidity, prolonged duration of ventilation stay costs for healthcare. It was shown that early diagnosis VAP immediate initiation appropriate antibiotics reduced morbidity mortality. The aim this study to evaluate the potential ability screening test based on clinical pulmonary score (CPIS) identify treat VAP.

10.1186/cc13494 article EN cc-by Critical Care 2014-03-17

There are a few reports in the literature about successful use of sugammadex treatment hypersensitivity reactions caused by rocuronium; however, pathophysiological mechanism is still unknown. This study aims to investigate changes rocuronium lung and effect on these with biochemical, light microscopic immunohistochemical parameters rat model.For study, 28-male Sprague-Dawley rats were randomly divided, seven each, into four groups. Group C (control) received only 0. 9 % NaCl without any...

10.15586/aei.v49i3.84 article EN Allergologia et Immunopathologia 2021-05-01

Background Epidural anesthesia is one of the best options for lower abdominal and limb surgery. However, there have been insufficient reports regarding use epidural pilonidal sinus The present study was performed to compare clinical profiles block with 0.75% levobupivacaine ropivacaine in this procedure. Methods Thirty patients undergoing surgery were randomly allocated into two groups: group received other at a volume 10 ml. Arterial blood pressure, heart rate, oxygen saturation, onset time...

10.4097/kjae.2015.68.2.141 article EN cc-by-nc Korean journal of anesthesiology 2015-01-01

Even endotracheal intubation could be considered safe in operations under general anesthesia; rarely, it cause recurrent laryngeal nerve paralysis as a complication. As mentioned the literature, possible reason for this, anterior branches of larynx suffer from compression between posteromedial part thyroid cartilage and cuff tube. In unilateral vocal cord due to occurs more frequently comparison bilateral paralysis. These types palsies usually totally improve approximately 6 months. A...

10.1097/scs.0b013e3182413d71 article EN Journal of Craniofacial Surgery 2012-01-01

Methylene tetrahydrofolate reductase (MTHFR) deficiency is an autosomal recessive disorder that results in increased homocysteine levels the body. Hyperhomocysteinemia causes a predisposition to venous and arterial thrombosis ischaemic insults. The incidence of around 40% some countries. In this study, we aimed evaluate effects anaesthetic agents children with MTHFR deficiency.Twelve paediatric patients enzyme who underwent surgery ten-month period single centre were retrospectively...

10.5152/tjar.2017.68366 article EN Türk anestezi ve reanimasyon dergisi 2017-04-28

Cyclopentolate is a frequently used topical mydriatic and cycloplegic drug by ophthalmologists for diagnosing preoperatively evaluating the patients.We aimed to report case of delirium due high dose cyclopentolate application an ophthalmologic examination.Cyclopentolate drops were in 6 years old male patient without any co-existing disease examination at ophthalmology polyclinic.However, it was applied 3-three times as 3 with 15 minutes intervals on his two eyes mother.After he experienced...

10.5152/jarem.2016.1011 article EN Journal of Academic Research in Medicine 2016-12-14

BACKGROUNDSedating the mechanically ventilated patients in intensive care unit (ICU) has a clinical prevalence, and aimed to reduce incompatibility with ventilator, increase intubation tolerance, anxiety, reducing recall of care, stress response oxygen consumption, prevent removal endotracheal tube, vascular catheter etc. by patients, adequacy patient services, provide good conditions for sleep protect providers from patient's agitating movements, treat delirium (1-4).The application...

10.20431/2455-9792.0301002 article EN ARC Journal of Anesthesiology 2018-01-01

Spinal Anestezi ile Yapılan Elektif Sezaryen Vakalarında Serebral Oksimetre Kullanımı: Randomize Prospektif ÇalışmaAim: To compare the effect of bupivacaine and bupivacaine/ fentanyl combination on cerebral oxygenation values with Near-infrared spectroscopy (NIRS) technique in elective cesarean sections performed under spinal anesthesia.Methods: Fifty patients who underwent section anesthesia were randomly divided into two groups.7.5-10 mg 0.5% hyperbaric was administered to group (n=25)...

10.4274/haseki.galenos.2021.6620 article EN cc-by-nc-nd Medical Bulletin of Haseki 2021-01-01
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