Uxío Calvo-Álvarez

ORCID: 0000-0002-5243-2767
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About
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Research Areas
  • Asthma and respiratory diseases
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Respiratory and Cough-Related Research
  • Inhalation and Respiratory Drug Delivery
  • Respiratory Support and Mechanisms
  • IL-33, ST2, and ILC Pathways
  • Pneumonia and Respiratory Infections
  • Gastric Cancer Management and Outcomes
  • Heart Failure Treatment and Management
  • Esophageal Cancer Research and Treatment
  • Gastrointestinal Tumor Research and Treatment
  • Emergency and Acute Care Studies
  • Appendicitis Diagnosis and Management
  • Mental Health Treatment and Access
  • Traumatic Ocular and Foreign Body Injuries
  • Head and Neck Cancer Studies
  • Trace Elements in Health
  • COVID-19 diagnosis using AI
  • MicroRNA in disease regulation
  • Peptidase Inhibition and Analysis
  • Eosinophilic Disorders and Syndromes
  • Extracellular vesicles in disease
  • Intraperitoneal and Appendiceal Malignancies
  • Health and Wellbeing Research
  • Diverticular Disease and Complications

Complejo Hospitalario Universitario de Ferrol
2015-2023

Complejo Hospitalario Universitario de Santiago
2009-2023

Ferro (United States)
2015

Complejo Hospitalario de Pontevedra
2011

Hospital Clínico Universitario de Valencia
2004

Abstract Background Frequent and highly prevalent as comorbidities in Chronic Obstructive Pulmonary Disease (COPD) patients, both depression anxiety seem to have an impact on COPD prognosis. However, they are underdiagnosed rarely treated properly. Aim To establish the prevalence of patients admitted for Acute Exacerbation (AECOPD) determine their influence Methods Prospective observational study conducted from October 1, 2016 2018 at following centers Galicia, Spain: Salnés County Hospital,...

10.1186/s12890-022-01934-y article EN cc-by BMC Pulmonary Medicine 2022-04-29

The most common electrolyte disorder among hospitalized patients, hyponatremia is a predictor of poor prognosis in various diseases. aim this study was to establish the prevalence patients admitted for acute exacerbation chronic obstructive pulmonary disease (AECOPD), as well its association with clinical progress. Prospective observational carried out from 1 October 2016 2018 following hospitals: Salnés Vilagarcía de Arousa, Arquitecto Marcide Ferrol, and University Hospital Complex...

10.3390/jcm9020503 article EN Journal of Clinical Medicine 2020-02-12

Background Eosinophils in peripheral blood are one of the emerging biomarkers chronic obstructive pulmonary disease (COPD) patients. However, when analysing relationship between eosinophilia and COPD prognosis, highly variable results obtained. The aim our study is to describe serum levels patients analyse their prognosis following hospital admission.Methods A prospective observational was conducted from 1 October 2016 2018 Spanish centres: Salnés County Hospital Vilagarcía de Arousa,...

10.1080/07853890.2021.1949489 article EN cc-by Annals of Medicine 2021-01-01

1 Introduction The aim of analysing the usefulness blood eosinophil count (BEC) as a prognostic marker in exacerbations patients with Chronic Obstructive Pulmonary Disease (COPD), evaluating its relationship hospital mortality, length stay and early late re-admissions. 2 Materials Methods We have carried out retrospective study including all who required admission from January 2008 to 31 December 2009, diagnosis on discharge COPD exacerbation. These were classified using three cut-off points...

10.1111/ijcp.13423 article EN International Journal of Clinical Practice 2019-10-01

Risk stratification of patients with COVID-19 can be fundamental to support clinical decision-making and optimize resources. The objective our study is identify among the routinely tested analytical parameters those that would allow us determine highest risk dying from COVID-19.

10.1016/j.opresp.2022.100162 article EN cc-by-nc-nd Open Respiratory Archives 2022-02-06

The relationship between obesity and asthma exacerbations is still under debate. aim of our work to analyse the hospital re-admissions in asthmatics. A review was retrospectively performed on all admissions adult patients due exacerbation occurring for 11 years. All those cases with as first diagnosis discharge report were included, or second provided when respiratory infection failure. Only admission each patient included this study. Odds Ratios a higher incidence early/late readmissions...

10.3390/jcm9010221 article EN Journal of Clinical Medicine 2020-01-14

Hospital admissions account for a significant part of asthma cost, but with differences between geographic areas.The aim our study is to analyse hospital due asthma, as well the factors associated longer stays.A review was retrospectively carried out on all patients over 18 years old exacerbation occurring in 2000 and 2010. The personal characteristics each patient, history, every exacerbation, treatment before admission after discharge were recorded.During period, there 2163 1316 (mean age...

10.1080/17843286.2017.1295524 article EN Acta Clinica Belgica 2017-03-01

COPD causes high morbidity and mortality health costs. Thus, identifying analyzing the distinctive treatable traits seems useful to optimize management of AEPOC patients. While various biomarkers have been researched, no solid data for systematic use made available.Assessing short-term prognostic usefulness clinical analytical parameters available in routine practice exacerbations.Multicenter prospective observational study conducted between 2016 2018. Patients admitted exacerbation who...

10.1016/j.opresp.2023.100271 article ES cc-by-nc-nd Open Respiratory Archives 2023-09-20

<b>Background:</b> Severe eosinophilic asthma (SEA) is a T2<sup>high</sup>-endotype with recurrent exacerbations and poor disease control. Mepolizumab (anti-IL5 mAb) decreases the number of peripheral blood eosinophils, but effect on their function poorly understood. Our aim was to identify changes in phenotype or activation eosinophils response mepolizumab patients SEA. <b>Methods:</b> Blood samples were collected from healthy controls (HC; n=10) SEA (n=12) before (T0) after treatment (T4,...

10.1183/13993003.congress-2023.oa4301 article EN 05.01 - Airway pharmacology and treatment 2023-09-09

El déficit de alfa-1 antitripsina (D-AAT) es una enfermedad genética, relativamente frecuente en poblaciones origen europeo.Frecuentemente está infradiagnosticada, con largos retrasos entre el inicio los síntomas respiratorios y diagnóstico definitivo.El D-AAT puede diagnosticarse la determinación niveles séricos esta proteína, y, cuando están por debajo del rango normal debe ser confirmado fenotipo.El seguimiento correcto progresión realizarse todos casos, ya que se asocia mejor...

10.4321/s1137-66272011000100012 article ES Anales del Sistema Sanitario de Navarra 2011-04-01

Abstract Background : Frequent and highly prevalent as comorbidities in Chronic obstructive pulmonary disease (COPD) patients, both depression anxiety seem to have an impact on COPD prognosis. However, they are underdiagnosed rarely treated properly. Aim establish the prevalence of patients admitted for acute exacerbation (AECOPD) determine their influence Methods: Prospective observational study conducted from October 1, 2016 2018 at following centers Galicia, Spain: Salnés County Hospital,...

10.21203/rs.3.rs-1311451/v1 preprint EN cc-by Research Square (Research Square) 2022-02-09

Asthma is a respiratory disease traditionally classified according to different phenotypes (e.g., allergic/non allergic) and endotypes (T2<sup>high</sup>/T2<sup>low</sup>) with strong influence of environmental triggers that vary seasonally, such as allergens, tobacco smoke, weather, contaminants, or viral infections. Exosomes are extracellular vesicles carry potential biomarkers, like microRNAs (miRNAs). Some miRNAs have been related asthma miR21, miR146a), allergic diseases miR16, miR126),...

10.1183/23120541.lsc-2022.97 article EN 2022-03-10

<b>Background:</b> The efficacy of mepolizumab in the treatment patients with severe eosinophilic asthma (SEA) is already known. However, it not yet known whether there any relationship between age and response to this treatment. <b>Objective:</b> To analyse impact on SEA. <b>Methods:</b> We carried out a multicentre (8 hospitals), retrospective study, including all adult SEA, whom was started, who had received at least one dose drug, follow-up 6 months. Three groups were defined according...

10.1183/13993003.congress-2023.pa4106 article EN 05.01 - Airway pharmacology and treatment 2023-09-09
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