A5024297094- Elasticity and Material Modeling
- Aortic aneurysm repair treatments
- Cardiovascular Health and Disease Prevention
- Aortic Disease and Treatment Approaches
- Cerebrovascular and Carotid Artery Diseases
- Bone health and osteoporosis research
- Elasticity and Wave Propagation
- Connective tissue disorders research
- Muscle activation and electromyography studies
- Coronary Interventions and Diagnostics
- Botulinum Toxin and Related Neurological Disorders
- Stroke Rehabilitation and Recovery
- Cerebral Palsy and Movement Disorders
- Sports injuries and prevention
- Cardiac, Anesthesia and Surgical Outcomes
- Composite Material Mechanics
- Electrospun Nanofibers in Biomedical Applications
- Composite Structure Analysis and Optimization
- Tendon Structure and Treatment
- Cellular Mechanics and Interactions
- Muscle Physiology and Disorders
- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Orthopaedic implants and arthroplasty
- Body Composition Measurement Techniques
Université Paris-Est Créteil
2015-2025
Paris-Est Sup
2023-2025
Hôpital Européen Georges-Pompidou
2001-2016
Université Paris Cité
1998-2016
Inserm
2001-2016
Centre National de la Recherche Scientifique
2002-2016
Bioingénierie, Tissus et Neuroplasticité
2016
Hôpital Européen
2001-2016
Paris Cardiovascular Research Center
2016
Délégation Paris 5
2008-2016
Background The Hemophilia Functional Ability Scoring Tool (Hemo-FAST), consisting of a patient-reported outcome (PRO) part and clinician-reported (ClinRO) part, was developed as rapid effective tool to assess functional mobility in clinical practice. This study (NCT04731701) aimed validate the psychometric properties Hemo-FAST for assessment joint health people with haemophilia (PwH). Methods PwH A or B aged ≥18 years completed questionnaires including PRO short-form 36 survey (SF-36) during...
Spastic paresis, a frequent consequence of stroke, is characterized by both neurological and muscular alterations, leading to decreased muscle strength, increased passive stiffness, subsequently, diminished functional capacity. Although conventional rehabilitation programs are effective in enhancing they often fail yield clinically significant improvements capacities. Eccentric Training (ET) has shown promise addressing the shortened fascicle lengths joint contractures commonly observed...
More real-world data are needed to complement existing phase III studies on the efficacy and safety of recombinant factor IX Fc fusion protein (rFIXFc) in people with haemophilia B. We report final from B-SURE study, evaluating usage effectiveness rFIXFc France. Previously treated patients (all ages/severities) received on-demand or prophylactic during B-SURE. Annualised bleeding rate (ABR), injection frequency (IF) consumption (FC) were prospectively evaluated for prophylaxis (primary...
ABSTRACT Background Haemophilia management aims to prevent bleeding and preserve joint function. Changes in patients’ health may influence physicians' decisions adjust treatment. The Joint Health Score (HJHS) Early Arthropathy Detection with Ultrasound (HEAD‐US) score assess but are not routinely used. Aim To evaluate whether systematic examination HJHS and/or HEAD‐US had an impact on treatment France, using final data from the A‐MOVE study. Methods (NCT04133883) was a 12‐month prospective,...
Carotid plaque rupture depends on the various types of mechanical stresses. Our objective was to determine multiaxial characteristics atherosclerotic and adjacent segment common carotid artery.A novel noninvasive echotracking system used measure intima-media thickness, diameter, pulsatile strain, distensibility at 128 sites a 4-cm long artery segment. The study included 62 patients with recent cerebrovascular ischemic event either far wall (n=25) or no (n=37).The devoid did not differ...
The analysis of plaque mechanics along the longitudinal axis (bending strain) may provide useful information because repetitive bending strain an atherosclerotic can fatigue wall material and result in rupture. Whether essential hypertension is associated with a specific pattern has not yet been determined. study included 92 patients on common carotid artery: 66 hypertension, either treated or not, 26 normotensive patients. A novel noninvasive echotracking system (ArtLab; Esaote,...
The arterial wall has generally been considered as noncompressible in vitro studies. However, compressibility of the (CAW) never studied vivo humans. Large interstitial proteoglycans play a major role sustaining compression generated by pulsatile forces. aims present study were to develop an experimental methodology for assessment CAW humans and patients with pseudoxanthoma elasticum (PXE), genetic disease characterized proteoglycan accumulation fragmented, swollen, calcified elastic fibers...
A novel approach that preserved most mesenchymal stem cell (MSC) characteristics was developed using MSC encapsulation in a hydrogel based on hyaluronic acid (HA). An optimized HA-hydrogel composition, whose were assessed by scanning electron microscopy and viscoelastic property analyses, as well the more favorable seeding density, established. These optimal three-dimensional culture conditions allowed morphological remodeling, maintained expression of markers over 28 days culture,...
Several studies have investigated muscle rigidity using SWE. However, the assessments may not consider most affected regions within same tissue nor intramuscular variability of between muscles group, e.g., plantar flexors. The data presented in this article aimed to explore inter–and flexors stiffness during prone and standing positions at different lengths healthy paretic individuals. Shear wave ultrasound images were acquired for three flexor (gastrocnemius medialis [GM], gastrocnemius...