A5030120117- Skin and Cellular Biology Research
- Dermatological and Skeletal Disorders
- Pluripotent Stem Cells Research
- Dupuytren's Contracture and Treatments
- Ion Transport and Channel Regulation
- Pharmacological Effects of Natural Compounds
- ATP Synthase and ATPases Research
- Parkinson's Disease Mechanisms and Treatments
- Wnt/β-catenin signaling in development and cancer
- Metabolism and Genetic Disorders
- Toxin Mechanisms and Immunotoxins
- Autoimmune Bullous Skin Diseases
- Nuclear Receptors and Signaling
- Phytochemistry and Bioactive Compounds
Shaheed Zulfiqar Ali Bhutto Institute of Science and Technology
2022
Quaid-i-Azam University
2019-2021
International Islamic University, Islamabad
2013
Walnut Oil and Caralluma are edible form part of the traditional medicine system in many countries. These frequently used as remedies to relieve a wide range illnesses health problems. species have demonstrated anti-inflammatory, anti-nociceptive, antidiabetics, hepatoprotective, gastric mucosa protecting, antimalarial, antioxidant, anti-trypanosomal, appetite suppressant cytotoxic activities. The current study was planned impacts 21 days' oral administration walnut oil methanolic extract...
Epidermolysis bullosa (EB) includes a group of rare gesnodermatoses that result in blistering and erosions the skin mucous membranes. Genetically, pathogenic variants around 20 genes are known to alter structural functional integrity intraepidermal adhesion dermo-epidermal anchorage, leading four different types EB. Here we report underlying genetic causes EB phenotypes segregating seven large consanguineous families, recruited from regions Pakistan. Whole exome sequencing, followed by...
Introduction: Primary distal renal tubular acidosis (dRTA) is a rare genetic disorder characterized by an impaired urinary acidification process in nephrons that results the production of alkaline urine. Loss function variants any three genes, ATP6V0A4, ATP6V1B1, or SLC4A1, which all play role normal urine kidneys, may lead to dRTA. Objective: This study was designed identify underlying dRTA Pakistani patients using whole exome sequencing, followed confirmatory Sanger sequencing. Materials...
Parkinson's disease involves a progressive loss of midbrain dopaminergic neurons in the substantia nigra, which causes motor symptoms such as dysfunctional bradykinesia, rigidity and tremor.Genetic mutations Parkinson are infrequent important because they represent potential therapeutic targets.Unfortunately, there is currently no treatment to stop progression but only few improvements accessible by current treatments based on levodopa therapy.Embryonic stem cells, Neural Mesenchymal cell...