A5025662278- Gastroesophageal reflux and treatments
- Gastrointestinal motility and disorders
- Esophageal and GI Pathology
- Dysphagia Assessment and Management
- Helicobacter pylori-related gastroenterology studies
- Eosinophilic Esophagitis
- Diet and metabolism studies
- Intestinal Malrotation and Obstruction Disorders
- Pelvic floor disorders treatments
- Congenital gastrointestinal and neural anomalies
- Intestinal and Peritoneal Adhesions
- Anorectal Disease Treatments and Outcomes
- Esophageal Cancer Research and Treatment
- Infant Health and Development
- Ocular Surface and Contact Lens
- Ion Channels and Receptors
- Child Nutrition and Feeding Issues
- Gallbladder and Bile Duct Disorders
- Cardiovascular Function and Risk Factors
- Sexual function and dysfunction studies
- Liver Disease Diagnosis and Treatment
- Hernia repair and management
- Tracheal and airway disorders
- Cardiovascular Syncope and Autonomic Disorders
- Pediatric Hepatobiliary Diseases and Treatments
University of Bologna
2013-2024
Policlinico S.Orsola-Malpighi
1999-2024
University of Padua
2007-2010
Cambridge University Press
2010
New York University Press
2010
University Gastroenterology
1999-2008
AstraZeneca (Poland)
2005
American Gastroenterological Association
2005
University of Campania "Luigi Vanvitelli"
1998
Mississippi State University
1998
BACKGROUND Dilation of intercellular spaces (DIS) human esophageal epithelium, evident at transmission electron microscopy (TEM), is an early marker damage caused by gastroesophageal reflux, but its reversibility after therapy has not been investigated. AIM To evaluate whether omeprazole can induce the healing DIS. METHODS Thirty-eight symptomatic patients, 22 with nonerosive reflux disease (NERD) and 16 erosive esophagitis (EE), classified on basis 24-h pH monitoring, were enrolled. During...
Summary Aim : To decrease the intensity of dyspeptic symptoms by impairing visceral nociceptive C‐type fibres with capsaicin, contained in red pepper powder. Methods The study was performed on 30 patients functional dyspepsia and without gastro‐oesophageal reflux disease irritable bowel syndrome. After a 2‐week washout period, 15 received, before meals randomly double‐blind manner, 2.5 g/day powder for 5 weeks, received placebo. A diary sheet given to each patient record, day, scores...
Summary Background : The dilation of oesophageal intercellular spaces, clearly apparent in transmission electron microscopy images, is a marker cellular damage induced by acid. Aim To analyse the presence dilated spaces and to quantify scores controls patients with gastro‐oesophageal reflux disease or duodenal accompanied erosive non‐erosive disease. Methods Thirty‐eight symptomatic 12 asymptomatic controls, classified on basis pH‐metry bilimetry, underwent endoscopy. Six tissue biopsies...
Gastric myoelectric and manometric activities were studied by means of a peroral probe in six patients with chronic idiopathic gastroparesis characterized marked delay gastric emptying at scintigraphy interdigestive hypokinesia manometry. Six normal subjects examined as controls. The study was carried out Ag‐AgCl suction‐needle electrodes an open‐tip catheter. In this method able to record the distal antrum regular occurrence pacesetter potentials frequency about three per minute associated...
A study was carried out in 30 patients affected by a mild or moderate degree of oesophageal achalasia to compare the clinical and manometric effects sublingual nifedipine pneumatic dilatation. Sixteen were dilated twice with Rider-Moeller dilators 14 treated 10-20 mg minutes before meals. evaluation performed six months after starting treatment. The (according Vantrappen9s criteria) every three for mean follow up 21 months. In both groups significant (p less than 0.001) fall lower sphincter...
Two patients with attacks of choking caused by aspiration gastric contents in the laryngotracheal tube are presented. One had such severe respiratory arrest, that tracheostomy was done. The common symptoms gastro-oesophageal reflux as pirosis, acid regurgitation, or retrosternal burning were absent both and upper gut radiological endoscopic examinations negative. Histology oesophageal mucosa showed a deep chronic eosophagitis, 24-hour pH-monitoring oesophagus frequent refluxes. Manometry...
AbstractBackground: As the gastric emptying time delay of patients with functional dyspepsia is not correlated severity complaints, we investigated pattern intragastric distribution a meal an ultrasonographic method in different groups dyspeptic patients. Methods: The final empyting and postprandial variations cross-sectional area antrum were measured ultrasonographically, symptoms scored 41 dysmotility-like dyspepsia, whom 31 did have digestive or systemic diseases known to affect gut...
Circadian antroduodenal motor activity was studied in 40 normal subjects by means of a portable recording system consisting computerized data logger and probe with microtransducers. The quantitative qualitative characteristics contraction events during the interdigestive digestive periods, as well awake asleep were analysed. composition timing meals night recumbence standardized. In spite high interindividual variability parameters, significant differences periods between waking sleep states...
Background: Sildenafil shows an intense and prolonged inhibitory effect on the smooth muscle cells of corpus cavernosum arterioles by blocking phosphodiesterase‐type 5, which inactivates nitric oxide‐stimulated cyclic guanosine monophosphate. Aim: To investigate whether this is also displayed musculature gastroduodenal tract. Methods: In 16 normal subjects, antroduodenal motility was recorded means a low‐compliance manometric system. Ten minutes after appearance phase III migrating motor...