C. Ruggiero

ORCID: 0000-0002-5275-2074
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Polymer Surface Interaction Studies
  • AI-based Problem Solving and Planning
  • Biomedical Text Mining and Ontologies
  • Machine Learning in Bioinformatics
  • Semantic Web and Ontologies
  • Protein Structure and Dynamics
  • Electrospun Nanofibers in Biomedical Applications
  • Bone Tissue Engineering Materials
  • Advanced Chemical Sensor Technologies
  • Electronic Health Records Systems
  • Computational Drug Discovery Methods
  • RNA and protein synthesis mechanisms
  • Dendrimers and Hyperbranched Polymers
  • Fractal and DNA sequence analysis
  • Nanoparticle-Based Drug Delivery
  • Genomics and Phylogenetic Studies
  • Nerve injury and regeneration
  • Enzyme Structure and Function
  • Nanofabrication and Lithography Techniques
  • Electrostatics and Colloid Interactions
  • 3D Printing in Biomedical Research
  • AI in cancer detection
  • Scientific Computing and Data Management
  • Cellular Mechanics and Interactions
  • Service-Oriented Architecture and Web Services

University of Genoa
2012-2022

Institute for Macromolecular Studies
2015

National Research Council
2015

University of Cyprus
2013

Chinese University of Hong Kong
2013

Applied Multilayers (United Kingdom)
2013

Massachusetts Institute of Technology
2011

University of Milan
2009

Universidade de São Paulo
2006

Karolinska Institutet
1999

In recent decades, climate change and a shortage of resources have brought about the need for technology in agriculture. Farmers been forced to use information innovation communication order enhance production efficiency crop resilience. Systems engineering infrastructure based on Internet Things (IoT) are main novel approaches that generated growing interest. agriculture, IoT solutions according challenges Industry 4.0 can be applied greenhouses. Greenhouses protected environments which...

10.3390/en15103834 article EN cc-by Energies 2022-05-23

Dysphagia is a swallowing disorder characterized by the difficulty in transferring solid foods and/or liquids from oral cavity to stomach, making autonomous and safe feeding problematic. The main problems deriving dysphagia are tracheo-bronchial aspiration, aspiration pneumonia, malnutrition dehydration. In order overcome dysphagia-induced problems, over years water food thickening has been used, focusing specifically on viscosity increase, but limited results have obtained. Elastic...

10.3389/fnut.2018.00068 article EN cc-by Frontiers in Nutrition 2018-08-07

We have fabricated nanoporous alumina surfaces by means of anodization in oxalic acid different conditions and used them as the substrates for growth cells from a human osteoblast-like cell line. The rough been compared both with smooth standard Petri dishes control commercial similar material. viability has assessed at culture times 4, 11, 18, 25 days vitro. It turned out that porous side galvanostatically performed to better than alumina, whereas potentiostatically all other times,...

10.1109/tnb.2013.2257835 article EN IEEE Transactions on NanoBioscience 2013-05-29

The fatty acid methyl ester composition of a total 71 marine strains representing the genera Alteromonas, Deleya, Oceanospirillum, and Vibrio was determined by gas-liquid chromatographic analysis. Over 70 different acids were found. predominant 16:0, 16:1 cis 9, summed-in-feature (SIF) 4 (15:0 iso 2OH and/or trans 9) SIF 7 (18:1 11, 18:1 6) for all considered, but minor quantitative variations could be used to distinguish genera. In addition conventional statistical processing method analyze...

10.1128/aem.62.6.2122-2132.1996 article EN Applied and Environmental Microbiology 1996-06-01

Layer by layer (LBL) assembly garnered considerable interest due to its ability generate multifunctional films with high tunability and versatility in terms of substrates polyelectrolytes, allowing the option use complex devices drugs.

10.1039/c9bm00979e article EN cc-by-nc Biomaterials Science 2019-10-17

Paclitaxel is one of the anticancer agents most often used in clinical oncology practice for treatment ovarian, breast and non-small cell lung cancers. Nanoengineered polymeric capsules (NPCs) represent a new very effective tool encapsulation smart release different compounds. In present work were fabricated by means layer-by-layer assembly oppositely charged polyelectrolytes onto colloidal particles, followed removal cores at low pH to obtain hollow microcapsules. was loaded into capsule....

10.1166/jnn.2009.1580 article EN Journal of Nanoscience and Nanotechnology 2009-08-29

Chitosan has been used for drug delivery applications many years, and pectin recently several biomedical too. Both chitosan have shown to possess mucoadhesive properties. We report the assembly characterization of biocompatible biodegradable multilayers based on layer-by-layer (LbL) deposition pectin. The dependence multilayer properties degree esterification pectin, as well pH, is characterized, mucoadhesiveness estimated at oral gastric pHs. LbL fabrication hollow capsules carried out...

10.1002/macp.201400576 article EN Macromolecular Chemistry and Physics 2015-03-17

Cells are sensitive both to the micro/nanotopographic and chemical features of their surrounding environment. The engineering surface properties biomaterials is then critical develop bioactive devices with which elicit appropriate cellular responses. To this regard, layer by (LBL) self assembly technique represents a simple versatile method modify deposition ultrathin films specific predetermined properties. In work biomimetic coatings containing fibronectin, an adhesive glycoprotein...

10.1002/jbm.b.30867 article EN Journal of Biomedical Materials Research Part B Applied Biomaterials 2007-05-18

Polyelectrolyte capsules are seen as promising nanotechnology based drug delivery systems. In previous works, we have demonstrated the possibility to fabricate bio-activated surface layer containing with improved features in terms of biocompatibility. this study, characterized permeability properties such towards low and high molecular weight molecules, including proteins. The results indicated that presence strongly affects loading capacity which was found be higher compared plain capsules....

10.1177/0885328212446358 article EN Journal of Biomaterials Applications 2012-05-04

A construct based on the electrostatic layer-by-layer self assembly technique has been fabricated, to be used as a tailored device encourage nerve regeneration. multilayered nanocoating composed of three precursor bilayers cationic poly(dimethyldiallylammonium) chloride (PDDA) and anionic poly(styrenesulfonate) (PSS), followed by poly-D-lysine (PDL) antibody specific transforming growth factor β1 (anti-TGF-β1), deposited HYAFF 11®. The process monitored quartz crystal microbalance (QCM) for...

10.1049/ip-nbt:20050030 article EN IEE Proceedings - Nanobiotechnology 2006-01-01
Coming Soon ...