- Pharmaceutical and Antibiotic Environmental Impacts
- Analytical chemistry methods development
- Water Treatment and Disinfection
- Antibiotics Pharmacokinetics and Efficacy
- Environmental Toxicology and Ecotoxicology
- Toxic Organic Pollutants Impact
- Bacterial Identification and Susceptibility Testing
- Water Quality Monitoring Technologies
- Antibiotic Resistance in Bacteria
- Analytical Chemistry and Chromatography
- Mass Spectrometry Techniques and Applications
- Wastewater Treatment and Reuse
- Pharmacological Effects and Assays
- Biosensors and Analytical Detection
University at Buffalo, State University of New York
2018-2024
State University of New York
2019
Buffalo BioLabs
2019
Despite large differences in removal efficiencies, all treatment processes investigated were sufficient preventing short-term behavioral effects zebrafish larvae.
Antimicrobial resistance is a worldwide problem that both pressing and challenging due to the rate at which it spreading, lack of understanding mechanisms link human, animal environmental sources contributing its proliferation. One knowledge gap requires immediate attention significance antimicrobial residues other pharmaceuticals are being discharged from wastewater treatment plants (WWTPs) on dissemination in environment. In this work we provide an approach develop harmonized analytical...
It has been debated whether wastewater treatment plants (WWTPs) primarily act to attenuate or amplify antibiotic resistance genes (ARGs). However, ARGs are highly diverse with respect their mechanisms, mobilities, and taxonomic hosts therefore behavior in WWTPs should not be expected universally conserved. We applied metagenomic sequencing influent effluent samples from 12 international classify the of specific entering exiting WWTPs. In total, 1079 different originating a variety bacteria...
The occurrence of antibiotics in the environment from discharges wastewater treatment plants (WWTPs) and land application antibiotic-laden manure animal agriculture is a critical global issue because these residues have been associated with increased emergence antibiotic resistance environment. In addition, other classes pharmaceuticals personal care products (PPCPs) found effluents municipal WWTPs, many which persist receiving environments. Analysis by liquid chromatography-tandem mass...
Pharmaceuticals in natural waters are considered emerging pollutants due to their low concentrations and the negative effects they pose environment. Common sources of such include untreated wastewater from hospitals, residential, industrial, agricultural sources. Many treatment methods only remove a subset all pharmaceuticals wastewater; remaining discharged into waters, ultimately drain coastal areas. Regions without proper especially susceptible contamination. This study deals with...
Nontarget analysis using liquid chromatography–high resolution mass spectrometry (LC–HRMS) is a valuable approach in characterizing for contaminants of emerging concern (CECs) the environment. In this study, wastewater and surface water samples from three locations Manila, Philippines were analyzed CECs nontarget with an LC-Orbitrap. A previously optimized semiautomated workflow was used data processing Compound Discoverer. total 157 compounds identified, 21 confirmed reference standards, 83...
To determine the influence of wastewater discharge on concentration contaminants emerging concern (CECs), and their ecological impacts fish; effluents from ten full-scale municipal treatment plants (WWTPs) that into Hudson River, surface waters, wild-caught fish samples were analyzed using liquid chromatography tandem mass spectrometry (LC/MS/MS). Analysis was based targeted detection 41 pharmaceuticals, non-targeted analysis (suspect screening) CECs high-resolution LC/MS/MS to increase...