- Bone Tissue Engineering Materials
- Antimicrobial Peptides and Activities
- Advanced ceramic materials synthesis
- RNA Interference and Gene Delivery
- Bacterial Infections and Vaccines
- Nanoparticles: synthesis and applications
- Orthopedic Infections and Treatments
- Dendrimers and Hyperbranched Polymers
- Material Dynamics and Properties
- Advanced Nanomaterials in Catalysis
- Bacteriophages and microbial interactions
- Nanocluster Synthesis and Applications
- Silicon Nanostructures and Photoluminescence
- Spectroscopy and Quantum Chemical Studies
- Gold and Silver Nanoparticles Synthesis and Applications
- RNA and protein synthesis mechanisms
- Dental materials and restorations
- Titanium Alloys Microstructure and Properties
- thermodynamics and calorimetric analyses
- Magnesium Alloys: Properties and Applications
- Orthopaedic implants and arthroplasty
Northeastern University
2019-2022
Universitat Rovira i Virgili
2017
Cancer is a disease with an enormous worldwide impact. One of the fatal complications in cancer patients are bacterial opportunistic infections. The use chemotherapeutic drugs made remission more frequent and prolonged patient survival, but, increased risk infections.Address current problem growing pandemic considering high risks infections, present study synthesized novel dendritic assembly silver (Ag)-platinum (Pt) nanoparticles.Nanoparticles were characterized by TEM analysis, composition...
Bacterial meningitis has become a global concern, because of the emergence antibiotic-resistant bacteria. It been demonstrated that liposomes can enter bacteria, thus providing possible treatment for numerous infections, including meningitis. Fusogenic are pH-sensitive with high capacity to fuse bacteria membrane and promote intracellular drug release. Moreover, this ability be improved by using cell-penetrating peptides (such as Tat47-57, which is peptide derived from Tat protein HIV). The...
Under the current climate, physicians prescribe antibiotics for treating bacterial infections, and such a limitation to single class of drugs is disadvantageous since antibiotic-resistant bacteria have adapted withstanding their stresses. Antibiotic alternatives are sought, herein metal nanoparticles comprised rare earth elements cerium yttrium were determined invoke toxicity on methicillin-resistant Staphylococcus aureus (MRSA) multi-drug-resistant strain Escherichia coli (MDR E. coli)....
Nanoparticles are promising alternatives to antibiotics since nanoparticles easy manufacture, non-toxic, and do not promote resistance. act via physical disruption of the bacterial membrane and/or generation high concentrations reactive-oxygen species locally. Potential for may be quantified by free energy methods, such as extended Derjuan-Landau-Verwey-Overbeek theory, which predicts initial surface-material interactions. The using enthalpies formation predict minimum inhibitory...