Valentina Lee

ORCID: 0000-0002-5345-1994
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About
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Research Areas
  • Laser-Plasma Interactions and Diagnostics
  • Plasma Diagnostics and Applications
  • Laser Design and Applications
  • Biochemical Acid Research Studies
  • Drug-Induced Hepatotoxicity and Protection
  • Particle Accelerators and Free-Electron Lasers
  • Gyrotron and Vacuum Electronics Research
  • Chronic Kidney Disease and Diabetes
  • Advanced Glycation End Products research
  • Laser-Matter Interactions and Applications
  • Nephrotoxicity and Medicinal Plants
  • Biochemical effects in animals
  • Acute Kidney Injury Research
  • Advanced Optical Sensing Technologies
  • Plasma Applications and Diagnostics
  • Economic and Technological Developments in Russia
  • Advancements in Photolithography Techniques
  • Immune Response and Inflammation
  • Ion-surface interactions and analysis
  • Atomic and Molecular Physics
  • Biomarkers in Disease Mechanisms
  • Pharmacological Effects of Natural Compounds
  • Human Health and Disease
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • 3D Modeling in Geospatial Applications

Karaganda Medical University
2016-2023

University of Colorado Boulder
2021-2022

Institute of Economics
2021

Ural Branch of the Russian Academy of Sciences
2021

California State University, Fresno
2018

Sources of high-energy photons have important applications in almost all areas research. However, the photon flux and intensity existing sources is strongly limited for energies above a few hundred keV. Here we show that high-current ultrarelativistic electron beam interacting with multiple submicrometer-thick conducting foils can undergo strong self-focusing accompanied by efficient emission gamma-ray synchrotron photons. Physically, originate from interaction near-field transition...

10.1103/physrevlett.126.064801 article EN cc-by Physical Review Letters 2021-02-12

BACKGROUND: At the present time alternation of oxidative metabolism is considered as one leading pathogenic mechanisms in development and progression community-acquired pneumonia (CAP). However nature direction protein changes CAP patient’s blood had been almost unexplored.AIM: To define modified proteins erythrocytes plasma patients.MATERIAL AND METHODS: Blood obtained from: 42 patients with moderate severity pneumonia, 12 grave 32 healthy volunteers. Content advanced oxidation products,...

10.3889/oamjms.2016.040 article EN Open Access Macedonian Journal of Medical Sciences 2016-03-11

10.1016/j.nima.2021.165210 article EN publisher-specific-oa Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment 2021-03-07

Abstract At the present time, available views show our limited knowledge of peculiarities functional status neutrophils and their metabolism in patients with community-acquired pneumonia (CAP). The studying changes metabolic can broaden about pathogenesis define datum points therapeutic effect. Purpose research: to oxidative stress activity level modification proteins CAP patients. Materials methods: obtained from 23 pneumonia. Control group consisting 19 healthy volunteers. reactive...

10.1515/cipms-2016-0001 article EN cc-by-nc-nd Current Issues in Pharmacy and Medical Sciences 2016-04-01

BACKGROUND: Drug-induced kidney disorder is a frequent adverse event which contributes to morbidity and even incapacitation. Our current knowledge of drug-induced disease limited due varying definitions injury, incomplete assessment concurrent risk factors, lack long term outcome reporting.
 AIM: The discovery development novel biomarkers local (renal) response mechanisms, can diagnose damage earlier more accurately, are needed for effective prevention nephrotoxicity.
 METHODS:...

10.3889/oamjms.2020.3559 article EN Open Access Macedonian Journal of Medical Sciences 2020-04-26

Introduction: Drug induced kidney disorder is a frequent adverse event which contributes to morbidity and even incapacitation. The discovery development of novel biomarkers local (renal) response mechanisms, are needed for effective prevention drug-induced nephrotoxicity. Objectives: main purpose our study was investigate the oxidative modifications proteins in blood plasma erythrocytes patients with nephropathies. Patients Methods: Around105 were divided into two groups: first group...

10.34172/jnp.2021.31 article EN cc-by Journal of Nephropathology 2020-11-02

Abstract Background and aim Finding metabolic risk factors for the development of lung damage in coal miners is one research priorities, as long it can improve understanding pathogenesis target organs due to occupational dust. Considering that burden diseases significant, there remains a need these professions, no etiological treatment, relevance such studies undeniable. Methods This analyzed intermediates purine metabolism, RNA, DNA, OMP acid soluble fractions blood plasma miners, depending...

10.21203/rs.3.rs-2830352/v1 preprint EN cc-by Research Square (Research Square) 2023-05-25

We present an experimental and simulation-based investigation of the temporal evolution light emission from a thin, laser-ionized Helium plasma source. demonstrate analytic model to calculate approximate scaling time-integrated, on-axis with initial density temperature, supported by experiment, which enhances understanding measurement for wakefield accelerator (PWFA) sources. Our simulates temperature using split-step Fourier code particle-in-cell (PIC) code. A fluid simulation is then used...

10.48550/arxiv.2309.10723 preprint EN cc-by arXiv (Cornell University) 2023-01-01

This work describes the physics of plasma waves and accelerators. The superiority accelerators over conventional has generated renewed interest in these devices with advent ultra-fast laser technology. ponderomotive force produced by ultra short pulses interacting is considered resulting acceleration gradient derived from first principles. Electron injection described. Beam driven, including electron beam proton beam, are proposed as future high energy

10.1063/1.5109558 article EN Journal of Undergraduate Reports in Physics 2018-01-01

The relevance of the study topic is due to deepening integration Russia and Belarus need identify joint priorities tools assess interaction regions in industrial technological development.The purpose this features systematize for government incentives increase labor productivity Belarus.The main stages are: comparison methodological approaches performance evaluation; comparative analysis level dynamics Russian Federation Republic Belarus; systematization instruments state stimulation...

10.2991/aebmr.k.210710.060 article EN cc-by-nc Advances in economics, business and management research/Advances in Economics, Business and Management Research 2021-01-01

Background. Drug induced kidney disorder (DIKD) is a frequent adverse event which contributes to morbidity and even incapacitation. Toxic nephropathy also one of the pathological syndromes or complications in acute alcohol poisoning (AAP). Recent years experience shows insensitivity serum creatinine early stages damage. NGAL has been shown as preferred marker damage variety clinical settings. However, no similar studies have performed patients with toxic nephropathy. The presence markers...

10.15690/vramn1392 article EN Annals of the Russian academy of medical sciences 2021-06-30
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