A5020530606- Advanced Neuroimaging Techniques and Applications
- Fetal and Pediatric Neurological Disorders
- Advanced MRI Techniques and Applications
- Neonatal and fetal brain pathology
- Advanced Research in Systems and Signal Processing
- Ultrasound Imaging and Elastography
- Reading and Literacy Development
- Evolutionary Psychology and Human Behavior
- Restless Legs Syndrome Research
- Advanced Data Processing Techniques
- Parkinson's Disease Mechanisms and Treatments
- Functional Brain Connectivity Studies
- MRI in cancer diagnosis
- Sparse and Compressive Sensing Techniques
- Stress Responses and Cortisol
- Eating Disorders and Behaviors
- Neurological disorders and treatments
- Face Recognition and Perception
- Electron and X-Ray Spectroscopy Techniques
- Integrated Circuits and Semiconductor Failure Analysis
- Advanced Electron Microscopy Techniques and Applications
- Visual Attention and Saliency Detection
- Neural Networks and Applications
- Mindfulness and Compassion Interventions
- Cognitive and developmental aspects of mathematical skills
University of Washington
2012-2019
Seattle University
2019
University of Washington Medical Center
2016
Imaging Center
2016
Vanderbilt University
2010
Haskins Laboratories
1998
Yale University
1998
Learning to read requires an awareness that spoken words can be decomposed into the phonologic constituents alphabetic characters represent. Such is characteristically lacking in dyslexic readers who, therefore, have difficulty mapping onto word. To find location and extent of functional disruption neural systems underlies this impairment, we used magnetic resonance imaging compare brain activation patterns nonimpaired subjects as they performed tasks made progressively greater demands on...
Purpose Maximization of the blood oxygen level–dependent (BOLD) functional MRI (fMRI) contrast requires echo time MR sequence to match T2* value tissue interest, which is expected be higher in fetal brain compared with a child or an adult. Methods values cortical plate/cortical gray matter utero healthy fetuses from mid‐gestation onward (20–36 gestational weeks) were measured using 3D maps calculated 2D dual‐echo T2*‐weighted data corrected for between‐slice motion and reconstructed 1.0 mm 3...
Recently, there has been considerable interest, especially for in utero imaging, the detection of functional connectivity subjects whose motion cannot be controlled while MRI scanner. These cases require two advances over current studies: (1) multiecho acquisitions and (2) post processing reconstruction that can deal with significant between slice during multislice protocols to allow ability detect temporal correlations introduced by spatial scattering slices into account. This article...
Objective To test the relationship of anxiety to caloric intake and food cue perception in women men. Methods Fifty-five twins (26 complete, 3 incomplete pairs; 51% women) underwent 2 functional magnetic resonance imaging (fMRI) scans (before after a standardized meal) then ate at an ad libitum buffet objectively assess intake. State trait were assessed using State-Trait Anxiety Inventory. During fMRI scans, participants viewed blocks fattening nonfattening images, nonfood objects. Results...
fMRI studies at standard-resolution (SR-fMRI) found responses in the fusiform face area (FFA) for non-face objects of expertise, but because high-resolution (HR-fMRI) FFA (e.g., Grill-Spector et al., 2006) and neurophysiology patches monkey brain (Tsao, reveal no reliable selectivity objects, to SR-fMRI could be due spatial blurring. As focus strongest claims modularity clearest predictions about expertise are critical evaluating claim that perception is a "cognitive function with its own...
Motion correction of MRI sequences is a very active area research. Several postprocessing techniques for volume and more recently slice have been proposed. Slice motion fMRI data typically involves iterative registration slices to target volume. The usually reconstructed at each iteration using current estimates, with all possible views the subject. However, in presence large movements, quality reconstruction can be greatly degraded without good initialization, this turn affect accuracy...
Reconstruction of white matter connectivity in the fetal brain from utero diffusion-weighted magnetic resonance imaging (MRI) faces many challenges, including subject motion, small anatomical scale, and limited image resolution signal. These issues are compounded by need to track significant changes structural throughout development. We present an automated method for improved reliability completeness tract extraction across a wide range gestational ages, based on geometry coherent patterns...
Understanding when and how resting state brain functional activity begins in the human is an increasing area of interest both basic neuroscience clinical evaluation during pregnancy after premature birth. Although fMRI studies have been carried out on pregnant women since 1990's, reliable mapping function utero extremely challenging problem due to unconstrained fetal head motion. Recent employed scrubbing exclude parts time series whole subjects from order control confounds Fundamentally,...
A major challenge for fMRI analysis of the developing brain is subject motion, which can corrupt T <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> <sup xmlns:xlink="http://www.w3.org/1999/xlink">∗</sup> -weighted (T -w) signal intensity with spin history effects. Multi echo multislice EPI acqusitions be used to create parameteric R mapping that provide independence from such variation. However, motion between slice acquisitions scatters...
Techniques for iterative reconstruction of magnetic resonance diffusion images from motion corrected multi-planar acquisitions are beginning to allow the use more complex models and tractography techniques study early brain connectivity. Many have been developed adult neonatal images. However, fundamental differences in underlying tissues, signal levels relative spatial resolution that available fetal studies mean these may need be significantly adapted deal with different challenges. Here...
The aim of this study was to examine the use R2* mapping in maternal and fetal sub-regions placenta with providing a reference for blood oxygenation levels during normative development. There have been number MR relaxation studies placental tissues in-utero, but none reported value changes age, or examined differences placenta. Here specialized long-duration Multi-frame imaging used create stable estimate values different regions healthy pregnant volunteers not imaged clinical reasons. 27...